Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Jean-François Dubremetz"'
Autor:
Maguy Hamie, Rania Najm, Carine Deleuze-Masquefa, Pierre Antoine Bonnet, Jean-François Dubremetz, Marwan El Sabban, Hiba El Hajj
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Toxoplasma gondii is a prevalent parasite of medical and veterinary importance. Tachyzoïtes and bradyzoïtes are responsible for acute and chronic toxoplasmosis (AT and CT), respectively. In immunocompetent hosts, AT evolves into a persistent CT, wh
Externí odkaz:
https://doaj.org/article/b01fac70466c4b6eb4135d538922689d
Autor:
Barbara A. Fox, Rebekah B. Guevara, Leah M. Rommereim, Alejandra Falla, Valeria Bellini, Graciane Pètre, Camille Rak, Viviana Cantillana, Jean-François Dubremetz, Marie-France Cesbron-Delauw, Gregory A. Taylor, Corinne Mercier, David J. Bzik
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Toxoplasma gondii evades host immunity to establish a chronic infection. Here, we assessed the role of parasitophorous vacuole (PV) membrane (PVM)- and intravacuolar network (IVN) membrane-localized dense granule (GRA) proteins in the develo
Externí odkaz:
https://doaj.org/article/ef77c5b30b284e599b6b47cf0cdd3e64
Autor:
Moyira Osny Aquino-Gil, Mattis Kupferschmid, Hosam Shams-Eldin, Jörg Schmidt, Nao Yamakawa, Marlène Mortuaire, Frédéric Krzewinski, Stéphan Hardivillé, Edgar Zenteno, Christian Rolando, Fabrice Bray, Eduardo Pérez Campos, Jean-François Dubremetz, Yobana Perez-Cervera, Ralph T. Schwarz, Tony Lefebvre
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
O-linked β-N-acetylglucosaminylation or O-GlcNAcylation is a widespread post-translational modification that belongs to the large and heterogeneous group of glycosylations. The functions managed by O-GlcNAcylation are diverse and include regulation
Externí odkaz:
https://doaj.org/article/bacfa7c78ffd4a08a9a63a85a587ae59
Autor:
Jodie Lopez, Amina Bittame, Céline Massera, Virginie Vasseur, Grégory Effantin, Anne Valat, Célia Buaillon, Sophie Allart, Barbara A. Fox, Leah M. Rommereim, David J. Bzik, Guy Schoehn, Winfried Weissenhorn, Jean-François Dubremetz, Jean Gagnon, Corinne Mercier, Marie-France Cesbron-Delauw, Nicolas Blanchard
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2273-2286 (2015)
Apicomplexa parasites such as Toxoplasma gondii target effectors to and across the boundary of their parasitophorous vacuole (PV), resulting in host cell subversion and potential presentation by MHC class I molecules for CD8 T cell recognition. The h
Externí odkaz:
https://doaj.org/article/bed759afc9704f54bdc70e40d2319003
Autor:
Mai Nguyen-Chi, Quang Tien Phan, Catherine Gonzalez, Jean-François Dubremetz, Jean-Pierre Levraud, Georges Lutfalla
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 871-882 (2014)
Zebrafish embryos and larvae are now well-established models in which to study infectious diseases. Infections with non-pathogenic Gram-negative Escherichia coli induce a strong and reproducible inflammatory response. Here, we study the cellular resp
Externí odkaz:
https://doaj.org/article/9db47b3c6f6549b989de7300348bdd9c
Autor:
Cyrille Botté, Nadia Saïdani, Ricardo Mondragon, Mónica Mondragón, Giorgis Isaac, Ernest Mui, Rima McLeod, Jean-François Dubremetz, Henri Vial, Ruth Welti, Marie-France Cesbron-Delauw, Corinne Mercier, Eric Maréchal
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 4, Pp 746-762 (2008)
Toxoplasma gondii is a unicellular parasite characterized by unique extracellular and intracellular membrane compartments. The lipid composition of subcellular membranes has not been determined, limiting our understanding of lipid homeostasis, contro
Externí odkaz:
https://doaj.org/article/a34bee4bbee341cdb837ab799d8db6fb
Autor:
Leah M Rommereim, Valeria Bellini, Barbara A Fox, Graciane Pètre, Camille Rak, Bastien Touquet, Delphine Aldebert, Jean-François Dubremetz, Marie-France Cesbron-Delauw, Corinne Mercier, David J Bzik
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159306 (2016)
Toxoplasma gondii actively invades host cells and establishes a parasitophorous vacuole (PV) that accumulates many proteins secreted by the dense granules (GRA proteins). To date, at least 23 GRA proteins have been reported, though the function(s) of
Externí odkaz:
https://doaj.org/article/50efb8f011c14294b5231bb87e8c5b4d
Autor:
Sebastian Niehus, Terry K Smith, Nahid Azzouz, Marco A Campos, Jean-François Dubremetz, Ricardo T Gazzinelli, Ralph T Schwarz, Françoise Debierre-Grockiego
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85386 (2014)
Glycosylphosphatidylinositols (GPIs) from several protozoan parasites are thought to elicit a detrimental stimulation of the host innate immune system aside their main function to anchor surface proteins. Here we analyzed the GPI biosynthesis of an a
Externí odkaz:
https://doaj.org/article/2201b14750bc4a0ba34742f808a5e44f
Autor:
Maria E Francia, Carly N Jordan, Jay D Patel, Lilach Sheiner, Jessica L Demerly, Justin D Fellows, Jessica Cruz de Leon, Naomi S Morrissette, Jean-François Dubremetz, Boris Striepen
Publikováno v:
PLoS Biology, Vol 10, Iss 12, p e1001444 (2012)
Apicomplexa are intracellular parasites that cause important human diseases including malaria and toxoplasmosis. During host cell infection new parasites are formed through a budding process that parcels out nuclei and organelles into multiple daught
Externí odkaz:
https://doaj.org/article/afd1d8a1dbc84f7dbc4aaa2bb4f9659d
Autor:
Mauld H Lamarque, Julien Papoin, Anne-Laure Finizio, Gaelle Lentini, Alexander W Pfaff, Ermanno Candolfi, Jean-François Dubremetz, Maryse Lebrun
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32457 (2012)
Apicomplexan parasites secrete and inject into the host cell the content of specialized secretory organelles called rhoptries, which take part into critical processes such as host cell invasion and modulation of the host cell immune response. The rho
Externí odkaz:
https://doaj.org/article/ad63c3ef71bb4abea48f0592938bd47f