Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jean-François eDesaphy"'
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Externí odkaz:
https://doaj.org/article/8dbb704393bd4b75b5a08a4191867d14
Autor:
Roberta eCarbonara, Alessia eCarocci, Julien eRoussel, Giuseppe eCrescenzo, Canio eBuonavoglia, Carlo eFranchini, Giovanni eLentini, Diana eConte Camerino, Jean-François eDesaphy
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Voltage-gated sodium channels are known to play a pivotal role in perception and transmission of pain sensations. Gain-of-function mutations in the genes encoding the peripheral neuronal sodium channels, hNav1.7-1.9, cause human painful diseases. Thu
Externí odkaz:
https://doaj.org/article/adaf1e51d697482db3307fd55b0a919d
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Externí odkaz:
https://doaj.org/article/efb82ebbfa1340698bf0cd6b66bdec94
Autor:
Jean-François eDesaphy, Antonella eDipalma, Teresa eCostanza, Roberta eCarbonara, Maria Maddalena eDinardo, Alessia eCatalano, Alessia eCarocci, Giovanni eLentini, Carlo eFranchini, Diana eConte Camerino
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
We previously showed that the β-adrenoceptor modulators, clenbuterol and propranolol, directly blocked voltage-gated sodium channels, whereas salbutamol and nadolol did not (Desaphy et al., 2003), suggesting the presence of two hydroxyl groups on th
Externí odkaz:
https://doaj.org/article/17242d9f29a4411aa34163d05448951e
Publikováno v:
Frontiers in Pharmacology, Vol 1 (2010)
Externí odkaz:
https://doaj.org/article/5c1ff253fec64846af62b6b095626506
Autor:
Paola eImbrici, Antonella eLiantonio, Giulia Maria eCamerino, Michela eDe Bellis, Claudia eCamerino, Antonietta eMele, Arcangela eGiustino, Sabata ePierno, Annamaria eDe Luca, Domenico eTricarico, Jean-Francois eDesaphy, Diana eConte
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
In the human genome more than 400 genes encode ion channels, which are transmembrane proteins mediating ion fluxes across membranes. Being expressed in all cell types, they are involved in almost all physiological processes, including sense perceptio
Externí odkaz:
https://doaj.org/article/feaa35f9093b4685a32b8d14c3fcf7a3
Autor:
Paola eImbrici, Concetta eAltamura, Mauro ePessia, Renato eMantegazza, Jean-Francois eDesaphy, Diana eConte Camerino
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
The voltage-dependent ClC-1 chloride channel belongs to the CLC channel/transporter family. It is a homodimer comprising two individual pores which can operate independently or simultaneously according to two gating modes, the fast and the slow gate
Externí odkaz:
https://doaj.org/article/2f761434904043819c885cf5eda09f6a