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pro vyhledávání: '"Jean-François Sabuco"'
Autor:
Elisabeth Genet, Laurent Pradier, Delphine Ibghi, Matilde Lopez-Grancha, Jean-François Sabuco, David Machnik, Patrick Bernardelli, Valerie Roudieres, AIain Krick, Carine Vincent, Nicolas Moindrot, Véronique Taupin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 378(3)
In Alzheimer disease (AD), the double-strand RNA-dependent kinase protein kinase R (PKR )/EIF2AK2 is activated in brain with increased phosphorylation of its substrate eukaryotic initiation factor 2α (eIF2α). AD risk-promoting factors, such as ApoE