Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jean-François Mirjolet"'
Autor:
Nerina Dodic, Nicolas Ancellin, Morgane Bordessoules, Anne Bouillot, Nathan Butin, Cedric Charrier, Marie-Helene Fouchet, Alain Laroze, Anne-Pascale Luzy, Alexandre Moquette, Julia Pilot, Guillaume Serin, Jean-François Mirjolet, Fabrice Viviani, Christophe Parsy
Publikováno v:
Cancer Research. 82:1398-1398
Small molecule macrocyclic kinase inhibitors have attracted significant attention in drug discovery over the past years with drugs approval such as lorlatinib demonstrating the clinical relevance of this approach. We developed our expertise to furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43208622e1ec3053ca749df5ec2fe81
https://doi.org/10.1158/1538-7445.am2022-1398
https://doi.org/10.1158/1538-7445.am2022-1398
Autor:
Lorenzo Pavarini, Delphine L. Lauté-Caly, Marsilio Adriani, Emma Hennessy, Aurélie Couturier-Maillard, Loïc Morgand, Tamas Sukei, Maria Christofi, Elisabeth Logan, Imke Mulder, Sophie Bourdot, Sylvie Maubant, Jean-François Mirjolet
Publikováno v:
Cancer Research. 80:6201-6201
Introduction: The human gut microbiota plays a role in modulating both intestinal and systemic immunity. Its importance in regulating anti-tumorigenic responses is now being explored, supported by evidence that the functional profile of the gut micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c59f81e611998056e0a6c4086bce43fc
https://doi.org/10.1158/1538-7445.am2020-6201
https://doi.org/10.1158/1538-7445.am2020-6201
Autor:
Marie-Claude Viaud-Massuard, Ludovic Juen, Ambrine Sahal, Jean-François Mirjolet, Camille Martin, Ofelia Feuillâtre, Pascal Grondin, Audrey Desgranges, Audrey Bertaux, Camille Gély, Guillaume Serin, Samira Benhamouche-Trouillet, Christine B. Baltus
Publikováno v:
Cancer Research. 80:4115-4115
Introduction: The Antibody-Drug Conjugates (ADCs)-based therapy has revealed a field of perspectives by increasing the specificity and the efficacy of the anti-tumoral drug treatment. McSAF is a company focused in bio-organic and bioconjugates chemis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d666a608c4786b701813ddcb614880e1
https://doi.org/10.1158/1538-7445.am2020-4115
https://doi.org/10.1158/1538-7445.am2020-4115
Autor:
Jos Joore, Henriëtte Leonore Lanz, Pauline Berger, Elodie Rajon, Karla Queiroz, Erik Walinga, Paul Vulto, Jean-François Mirjolet, Fabrice Viviani, Silvia Bonilla, Remko van Vught
Publikováno v:
Cancer Research. 80:2795-2795
Predicting clinical response to anticancer drugs remains a major challenge in cancer therapy research. The current treatment of patients with ovarian cancer involves surgery and platinum-based chemotherapy, which still result in recurrence on advance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d75b0f8910d2ed0b5575585491f218
https://doi.org/10.1158/1538-7445.am2020-2795
https://doi.org/10.1158/1538-7445.am2020-2795
Autor:
Caroline Mignard, Olivier Duchamp, Josselin Caradec, Francis Bichat, Damien France, Fabrice Viviani, Jean François Mirjolet
Publikováno v:
Molecular Cancer Therapeutics. 18:LB-B01
Immunotherapy is one of the most exciting recent breakthroughs in the field of cancer treatment. Different approaches are developed such as cancer vaccines, adoptive cellular immunotherapy or immune checkpoint blockade, and a number have been regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64ce5f1862ef461357a40ec2f51de677
https://doi.org/10.1158/1535-7163.targ-19-lb-b01
https://doi.org/10.1158/1535-7163.targ-19-lb-b01
Autor:
Didier Grillot, Fabrice Viviani, Akanksha Gangar, Raphaelle Guillard-Huet, Jean-François Mirjolet
Publikováno v:
Cancer Research. 79:585-585
Immunological cell death (ICD) is a form of cancer cell death induced by radiotherapy, photodynamic therapy and a few chemotherapeutic agents such as Doxorubicin, Mitoxantrone, and Oxaliplatin. Unlike apoptosis or necrosis, ICD can induce an effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aca5d55c2072fbaa3a9213e6d851f09
https://doi.org/10.1158/1538-7445.am2019-585
https://doi.org/10.1158/1538-7445.am2019-585
Autor:
Tomofumi Miyamoto, Marie Aleth Lacaille-Dubois, Jean François Mirjolet, Chiaki Tanaka, Anne Claire Mitaine-Offer, Gaoussou Timité, Olivier Duchamp
Publikováno v:
Phytochemistry. 88:61-66
A phytochemical analysis of the whole plant of Allium schoenoprasum , has led to the isolation of four spirostane-type glycosides ( 1 – 4 ), and four known steroidal saponins. Their structures were elucidated mainly by 2D NMR spectroscopic analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b33b81d6770068b539b26f6fbcec7b
https://doi.org/10.1016/j.phytochem.2012.12.001
https://doi.org/10.1016/j.phytochem.2012.12.001
Autor:
Andrew Tsotinis, Stavroula Georgakopoulou, Stefanos Riganas, Jean-François Mirjolet, Maria Theodoropoulou, Margarita Prassa, Vassilios I. Moutsos, Andreas Eleutheriades, Guillaume Serin, Alexandre Vamvakides, Humaira Khan, Angeliki Zaniou, Athanasios Mantelas, Ioannis Papanastasiou, George B. Foscolos, Kostas Dimas, Stavroula Pondiki, Vassilios N. Kourafalos
Publikováno v:
Journal of Medicinal Chemistry. 55:10241-10261
The synthesis of the adamantane phenylalkylamines 2a-d, 3a-c, and 4a-e is described. These compounds exhibited significant antiproliferative activity, in vitro, against eight cancer cell lines tested. The σ(1), σ(2), and sodium channel binding affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7d92d915313f76ad8e08acaf62cf05
https://doi.org/10.1021/jm3013008
https://doi.org/10.1021/jm3013008
Autor:
Chiaki Tanaka, Mahenina Jaovita Manase, Jean François Mirjolet, Tomofumi Miyamoto, Anne Claire Mitaine-Offer, Marie Aleth Lacaille-Dubois, Olivier Duchamp, David Pertuit, Stéphanie Delemasure, Patrick Dutartre
Publikováno v:
Fitoterapia. 83:1115-1119
A new spirostanol saponin (1), along with four known saponins, dioscin (2), protodioscin (3), methyl-protodioscin (4), and indioside D (5), and one known steroid glycoalkaloid solamargine (6) were isolated from the two synonymous species, Solanum inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c278498c01d5cc54f7e2a609b97811a0
https://doi.org/10.1016/j.fitote.2012.04.024
https://doi.org/10.1016/j.fitote.2012.04.024
Autor:
Andrew Tsotinis, Margarita Prassa, Guillaume Serin, Ioannis Papanastasiou, Humaira Khan, Stavroula Georgakopoulou, Vassilios I. Moutsos, Jean-Jacques Bourguignon, Jean-François Mirjolet, Vassilios N. Kourafalos, Angeliki Zaniou, Alexandre Vamvakides, Stavroula Pondiki, Stefanos Riganas, Andreas Eleutheriades, George B. Foscolos, Kostas Dimas, Maria Theodoropoulou
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:3323-3331
The synthesis of N-{4-[a-(1-adamantyl)benzyl]phenyl}piperazines 2a-e is described. The in vitro antiproliferative activity of most compounds against main cancer cell lines is significant. The σ(1), σ(2)-receptors and sodium channels binding affinit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f08a918951df6498e0fc5e76bc3786e4
https://doi.org/10.1016/j.bmc.2012.03.038
https://doi.org/10.1016/j.bmc.2012.03.038