Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jean-François Gélinas"'
Publikováno v:
MethodsX, Vol 7, Iss , Pp 100806- (2020)
The recombinant Vesicular Stomatitis Virus (rVSV) is an emerging platform for viral vector-based vaccines. Promising results have been reported in clinical trials for the rVSV-ZEBOV vaccine for Ebola virus disease prevention. In this study, we descri
Externí odkaz:
https://doaj.org/article/0eb9816a8f8c48b5b0a3ef7a4673bfdc
Autor:
Aline Do Minh, Alexandra T. Star, Jacek Stupak, Kelly M. Fulton, Arsalan S. Haqqani, Jean-François Gélinas, Jianjun Li, Susan M. Twine, Amine A. Kamen
Publikováno v:
Viruses, Vol 13, Iss 5, p 797 (2021)
Lentiviral vectors (LVs) are a powerful tool for gene and cell therapy and human embryonic kidney cells (HEK293) have been extensively used as a platform for production of these vectors. Like most cells and cellular tissues, HEK293 cells release extr
Externí odkaz:
https://doaj.org/article/ae60cfc5f989402bb956d971cc196cd8
Autor:
Jannie Perdersen, Parminder S. Chahal, Stéphane Lanthier, Gary P. Kobinger, Sascha Kiesslich, Hiva Azizi, Jean-François Gélinas, Amine Kamen, Sven Ansorge, Rénald Gilbert
Publikováno v:
Vaccine. 37:6624-6632
Ebola virus disease is an urgent international priority. Promising results for several vaccine candidates have been reported in non-human primate studies and clinical trials with the most promising being the rVSV-ZEBOV vaccine. In this study, we soug
Autor:
Amine Kamen, Susan M. Twine, Jean-François Gélinas, Alexandra T. Star, Jacek Stupak, Arsalan S. Haqqani, Aline Do Minh, Kelly M. Fulton, Jianjun Li
Publikováno v:
Viruses, Vol 13, Iss 797, p 797 (2021)
Viruses
Volume 13
Issue 5
Viruses
Volume 13
Issue 5
Lentiviral vectors (LVs) are a powerful tool for gene and cell therapy and human embryonic kidney cells (HEK293) have been extensively used as a platform for production of these vectors. Like most cells and cellular tissues, HEK293 cells release extr
Autor:
Alexandra T. Star, Jacek Stupak, Amine Kamen, Susan M. Twine, Aline Do Minh, Jianjun Li, Jean-François Gélinas
Lentiviral vectors (LVs) are a powerful tool for gene and cell therapy and human embryonic kidney cells (HEK293) have been extensively used as a platform for production of these vectors. Like most cells and cellular tissues, HEK293 cells release extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67191f754e503b3f44dc6621e102d0a4
https://doi.org/10.20944/preprints202103.0696.v1
https://doi.org/10.20944/preprints202103.0696.v1
Autor:
Amine Kamen, Gary P. Kobinger, Anahita Bakhshizadeh Gashti, Mathias Mangion, Hiva Azizi, Sascha Kiesslich, Rénald Gilbert, Parminder S. Chahal, Jean-François Gélinas, Nasha Nassoury, Bruno Gaillet, Alain Garnier
Publikováno v:
Vaccine. 38(50)
Acquired Immune Deficiency Syndrome (AIDS) in humans is a result of the destruction of the immune system caused by Human Immunodeficiency Virus (HIV) infection. This serious epidemic is still progressing world-wide. Despite advances in treatment, a s
Autor:
Sven Ansorge, Sean Nesdoly, Amine Kamen, David M. Sharon, Yu Xia, Hsin J. Yang, Jean-François Gélinas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Cell-derived influenza vaccines provide better protection and a host of other advantages compared to the egg-derived vaccines that currently dominate the market, but their widespread use is hampered by a lack of high yield, low cost production platfo
Publikováno v:
Journal of biotechnology. 310
Ebola virus disease outbreaks have repeatedly occurred on the African continent over the last decades, with more serious outbreaks in recent years. Being highly transmissible and associated to high fatality rates, it constitutes a serious threat to p
Autor:
Eileen Shaw, Lucile Sinck, Guerline Clerzius, Rekha C. Patel, Aïcha Daher, Jean-François Gélinas, Thornin Ear, Andrew J. Mouland, Jean-Pierre Routy, Samantha Burugu, Anne Gatignol
Publikováno v:
Retrovirology
Background HIV-1 translation is modulated by the activation of the interferon (IFN)-inducible Protein Kinase RNA-activated (PKR). PKR phosphorylates its downstream targets, including the alpha subunit of the eukaryotic translation Initiation Factor 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91aac044784f392490cc6578caee06ee
https://doi.org/10.1186/1742-4690-10-96
https://doi.org/10.1186/1742-4690-10-96
Autor:
Kamila M Pytel, Jean-François Gélinas, Deborah R. Gill, Lee A. Davies, Amit C. Nathwani, Stephen C. Hyde, Lidia Cammack, Makoto Inoue, Ian A. Pringle, Caroline Moran, Eric W.F.W. Alton, S Tsugumine, Michael C. Paul-Smith, Mario Chan, Takashi Hironaka, Loren Cameron, Cuixiang Meng, Uta Griesenbach, Jenny McIntosh, Robyn V. Bell
Publikováno v:
Gene Therapy
We have shown that a lentiviral vector (rSIV.F/HN) pseudotyped with the F and HN proteins from Sendai virus generates high levels of intracellular proteins after lung transduction. Here, we evaluate the use of rSIV.F/HN for production of secreted pro