Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Jean-François Fonteneau"'
Autor:
Maureen Labbé, Manon Chang, Benjamin Saintpierre, Franck Letourneur, Laurence de Beaurepaire, Joëlle Véziers, Sophie Deshayes, Marine Cotinat, Jean-François Fonteneau, Christophe Blanquart, Vincent Potiron, Stéphane Supiot, Delphine Fradin
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-12 (2024)
Abstract Radiotherapy represents a major curative treatment for prostate cancer (PCa), but some patients will develop radioresistance (RR) and relapse. The underlying mechanisms remain poorly understood, and miRNAs might be key players in the acquisi
Externí odkaz:
https://doaj.org/article/0fc0b34f43f243738215274c3fef238f
Autor:
Pauline Hulo, Sophie Deshayes, Judith Fresquet, Anne-Laure Chéné, Stéphanie Blandin, Nicolas Boisgerault, Jean-François Fonteneau, Lucas Treps, Marc G Denis, Jaafar Bennouna, Delphine Fradin, Elvire Pons-Tostivint, Christophe Blanquart
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Lung cancers represent the main cause of cancer related-death worldwide. Recently, immunotherapy alone or in combination with chemotherapy has deeply impacted the therapeutic care leading to an improved overall survival. However,
Externí odkaz:
https://doaj.org/article/f68caea1887141088437dadc9d5e46a0
Autor:
Ugo Hirigoyen, Coraly Guilbaud, Morgane Krejbich, Morgane Fouet, Judith Fresquet, Bastien Arnaud, Emmanuelle Com, Charles Pineau, Gwenann Cadiou, Julien Burlaud-Gaillard, Philippe Erbs, Delphine Fradin, Nathalie Labarrière, Jean-François Fonteneau, Tacien Petithomme, Nicolas Boisgerault
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200887- (2024)
Extracellular vesicles (EVs) are mediators of intercellular communication in the tumor microenvironment. Tumor EVs are commonly associated with metastasis, immunosuppression or drug resistance. Viral infections usually increase EV secretion, but litt
Externí odkaz:
https://doaj.org/article/476ae58ab35d439fa36d12f1b6f5d08e
Autor:
Camille Chatelain, Laurine Berland, Marion Grard, Nicolas Jouand, Judith Fresquet, Joëlle Nader, Ugo Hirigoyen, Tacien Petithomme, Chantal Combredet, Elvire Pons-Tostivint, Delphine Fradin, Lucas Treps, Christophe Blanquart, Nicolas Boisgerault, Frédéric Tangy, Jean-François Fonteneau
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Attenuated measles virus (MV) exerts its oncolytic activity in malignant pleural mesothelioma (MPM) cells that lack type-I interferon (IFN-I) production or responsiveness. However, other cells in the tumor microenvironment (TME), such as myeloid cell
Externí odkaz:
https://doaj.org/article/b3ba27ed694c4cdcb2a9450d7b9a6e6f
Autor:
Ananya Hariharan, Weihong Qi, Hubert Rehrauer, Licun Wu, Manuel Ronner, Martin Wipplinger, Jelena Kresoja‐Rakic, Suna Sun, Lucia Oton‐Gonzalez, Marika Sculco, Véronique Serre‐Beinier, Clément Meiller, Christophe Blanquart, Jean‐François Fonteneau, Bart Vrugt, Jan Hendrik Rüschoff, Isabelle Opitz, Didier Jean, Marc dePerrot, Emanuela Felley‐Bosco
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3949-3974 (2022)
We previously observed increased levels of adenosine‐deaminase‐acting‐on‐dsRNA (Adar)‐dependent RNA editing during mesothelioma development in mice exposed to asbestos. The aim of this study was to characterize and assess the role of ADAR
Externí odkaz:
https://doaj.org/article/68417b6aa7474f1b8efa6a6d5df04297
TP53 mutations correlate with the non‐coding RNA content of small extracellular vesicles in melanoma
Autor:
Maureen Labbé, Estelle Menoret, Franck Letourneur, Benjamin Saint‐Pierre, Laurence deBeaurepaire, Joëlle Veziers, Brigitte Dreno, Marc G. Denis, Christophe Blanquart, Nicolas Boisgerault, Jean‐François Fonteneau, Delphine Fradin
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 8, Pp n/a-n/a (2023)
Abstract Non‐coding RNAs (ncRNAs) are important regulators of gene expression. They are expressed not only in cells, but also in cell‐derived extracellular vesicles (EVs). The mechanisms controlling their loading and sorting remain poorly underst
Externí odkaz:
https://doaj.org/article/782c4b8f9bf447e38e1bc9e1dc7db0ed
Autor:
Marine Charrier, Judith Lorant, Rafael Contreras-Lopez, Gautier Téjédor, Christophe Blanquart, Blandine Lieubeau, Cindy Schleder, Isabelle Leroux, Sophie Deshayes, Jean-François Fonteneau, Candice Babarit, Antoine Hamel, Armelle Magot, Yann Péréon, Sabrina Viau, Bruno Delorme, Patricia Luz-Crawford, Guillaume Lamirault, Farida Djouad, Karl Rouger
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Background Muscular dystrophies (MDs) are inherited diseases in which a dysregulation of the immune response exacerbates disease severity and are characterized by infiltration of various immune cell types leading to muscle inflammation, fibe
Externí odkaz:
https://doaj.org/article/6a5a488a3cc3450f87dd3f6ac422f0bc
Autor:
Suna Sun, MD, Weihong Qi, PhD, Hubert Rehrauer, PhD, Manuel Ronner, Ananya Hariharan, MSc, Martin Wipplinger, MSc, Clément Meiller, Msc, Rolf Stahel, MD, Martin Früh, MD, Ferdinando Cerciello, MD, PhD, Jean-François Fonteneau, PhD, Didier Jean, PhD, Emanuela Felley-Bosco, PhD, PD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 12, Pp 100430- (2022)
Introduction: The aim of this study was to investigate endogenous retrovirus (ERV) expression and type I interferon (IFN) activation in human pleural mesothelioma (PM) and their association with clinical outcome. Methods: The expression of ERV was de
Externí odkaz:
https://doaj.org/article/103818aaa4c24187ae63f2c4ea807f4b
Autor:
Pierre Autin, Sophie Deshayes, Juliette Lea, Nicolas Boisgerault, Emilie Dupré, Nathalie Labarrière, Rémy Leguevel, Jean-François Fonteneau, Christophe Blanquart, Delphine Fradin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
DCMU [N-(3,4-dichlorophenyl)-N-dimethylurea] or diuron is a widely used herbicide, which can cause adverse effects on human, especially on immune cells, due to their intrinsic properties and wide distribution. These cells are important for fighting n
Externí odkaz:
https://doaj.org/article/608a792705a544f8b67e09e092f34298
Autor:
Tiphaine Delaunay, Joelle Nader, Marion Grard, Isabelle Farine, Vera Hedwig, Johann Foloppe, Thibaut Blondy, Mathilde Violland, Daniel Pouliquen, Marc Grégoire, Nicolas Boisgerault, Philippe Erbs, Jean-François Fonteneau
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 573-578 (2020)
Malignant pleural mesothelioma (MPM) is a cancer of the pleura that lacks efficient treatment. Oncolytic immunotherapy using oncolytic vaccinia virus (VV) may represent an alternative therapeutic approach for the treatment of this malignancy. Here, w
Externí odkaz:
https://doaj.org/article/6d67b79df4734bc992cb612a228e36e2