Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jean-François Denis"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/776c6174f3cd4c9da0f829fb3958f213
Autor:
Éric Villiard, Jean-François Denis, Faranak Sadat Hashemi, Sebastian Igelmann, Gerardo Ferbeyre, Stéphane Roy
Publikováno v:
Biology Open, Vol 6, Iss 6, Pp 891-896 (2017)
Senescence represents a mechanism to avoid undesired cell proliferation that plays a role in tumor suppression, wound healing and embryonic development. In order to gain insight on the evolution of senescence, we looked at its presence in developing
Externí odkaz:
https://doaj.org/article/e8eced36598a4c35a03acb639589ff03
Autor:
Jean-François Denis, Mannekomba R. Diagbouga, Filippo Molica, Aurélie Hautefort, Tanja Linnerz, Masakatsu Watanabe, Sylvain Lemeille, Julien Y. Bertrand, Brenda R. Kwak
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Shear stress, a blood flow-induced frictional force, is essential in the control of endothelial cell (EC) homeostasis. High laminar shear stress (HLSS), as observed in straight parts of arteries, assures a quiescent non-activated endothelium through
Externí odkaz:
https://doaj.org/article/d4e39aa6517b4912b2f208c2ef0119b3
Autor:
Gauthier Schang, Mathilde Poujol De Molliens, Emilie Brule, Cristina Chauvet, Jean-François Denis, Vannakambadi Ganesh, Julia Schoelermann, Gilles Tremblay, Ilia Tikhomirov
Publikováno v:
Journal of the American College of Cardiology. 81:1894
Autor:
GAUTHIER GS SCHANG, EMILIE BRÛLÉ, JEAN-FRANÇOIS DENIS, MATHILDE POUJOL DE MOLLIENS, CRISTINA CHAUVET, VANNAKAMBADI GANESH, JULIA SCHOELERMANN, GILLES TREMBLAY, ILIA TIKHOMIROV, MAUREEN O'CONNOR
Publikováno v:
Chest. 162:A2365-A2366
Autor:
Gilles Tremblay, Jean-François Denis, Debra L. Wood, Nehal Lakhani, Daniel Vilarim Araujo, Timothy A. Yap, Tina Gruosso, Maureen D. O'Connor-McCourt, Ria Ghosh, Lilian Siu, Sandra Sinclair, Paul I. Nadler
Publikováno v:
Poster Presentations.
Background AVID200 is a rationally designed first-in-class receptor ectodomain trap that inhibits transforming growth factor-beta (TGF-beta) isoforms -beta1 and -beta3 with pM potency. TGF-beta signaling is highly immunosuppressive in the tumor micro
Autor:
Faranak Sadat Hashemi, Jean-François Denis, Stéphane Roy, Sebastian Igelmann, Gerardo Ferbeyre, Éric Villiard
Publikováno v:
Biology Open, Vol 6, Iss 6, Pp 891-896 (2017)
Biology Open
Biology Open
Senescence represents a mechanism to avoid undesired cell proliferation that plays a role in tumor suppression, wound healing and embryonic development. In order to gain insight on the evolution of senescence, we looked at its presence in developing
Publikováno v:
Oral Diseases. 24:509-517
The ability to regenerate damaged tissues would be of tremendous benefit for medicine and dentistry. Unfortunately, humans are unable to regenerate tissues such as teeth and fingers or to repair injured spinal cord. With an aging population, health p
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Axolotls have the amazing ability to regenerate. When compared to humans, axolotls display a very fast wound closure, no scarring and are capable to replace lost appendages perfectly. Understanding the signaling mechanism leading to this perfect heal
Autor:
James Koropatnick, Tina Gruosso, Gilles Tremblay, Jean-François Denis, Rene Figueredo, Maureen D. O'Connor-McCourt
Publikováno v:
Cancer Research. 80:6710-6710
AVID200 is a first-in-class rationally designed receptor ectodomain trap that selectively neutralizes TGF-beta 1 and -beta 3 with pM potency while sparing TGF-beta 2, thereby reducing the potential for toxicities associated with neutralization of thi