Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jean-François Dedieu"'
Autor:
Raphael Schiffmann, Timothy M Cox, Jean-François Dedieu, Sebastiaan J M Gaemers, Julia B Hennermann, Hiroyuki Ida, Eugen Mengel, Pascal Minini, Pramod Mistry, Petra B Musholt, David Scott, Jyoti Sharma, M Judith Peterschmitt
Gaucher disease type 3 is a chronic neuronopathic disorder with wide-ranging effects, including hepatosplenomegaly, anaemia, thrombocytopenia, skeletal disease and diverse neurological manifestations. Biallelic mutations in GBA1 reduce lysosomal acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed219c4759532a6c770f7c376cc91518
https://www.repository.cam.ac.uk/handle/1810/342736
https://www.repository.cam.ac.uk/handle/1810/342736
Autor:
Bingzhi Zhang, Judith Peterschmitt, Sebastiaan J.M. Gaemers, Julia B. Hennermann, Jyoti Sharma, Raphael Schiffmann, Eugen Mengel, Pramod K. Mistry, Jean-François Dedieu, Petra B. Musholt, Hiroyuki Ida, Timothy M. Cox
Publikováno v:
Molecular Genetics and Metabolism. 129:S144-S145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0a53ee6c3b00641e242c6bf003323b
https://doi.org/10.1016/j.ymgme.2019.11.382
https://doi.org/10.1016/j.ymgme.2019.11.382
Autor:
Jean François Dedieu, Jyoti Sharma, Mark N. Stein, Anne Frédérique Ghuysen, Patricia LoRusso, Gerald Edelman, Janice M. Mehnert, Joanne Lager, Li Liu, Heather Camisa
Publikováno v:
Investigational new drugs. 36(1)
Background Voxtalisib, a PI3K/mTOR inhibitor, has shown antitumor activity in capsule formulation in patients with solid tumors. This Phase I study assessed safety and pharmacokinetics of voxtalisib administered as immediate-release tablets in patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d206440d324731c2657f39453f87b4
https://pubmed.ncbi.nlm.nih.gov/28417284
https://pubmed.ncbi.nlm.nih.gov/28417284
Autor:
Laurent Kassalow, Jean François Dedieu, Monica M. Mita, John C. Morris, James L. Wade, John Sarantopoulos, Claudine Wack, Alain C. Mita, A. Craig Lockhart, Olivier Rixe
Publikováno v:
Cancer Chemotherapy and Pharmacology. 74:1113-1124
Cabazitaxel is primarily metabolized by CYP3A. This study evaluated the impact of moderate/strong CYP3A inhibitors [aprepitant (Study Part 2); ketoconazole (Study Part 3)] or strong CYP3A inducers [rifampin (Study Part 4)] on the pharmacokinetics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4229a99438c9744438a0ae7e30ae286
https://doi.org/10.1007/s00280-014-2572-z
https://doi.org/10.1007/s00280-014-2572-z
Autor:
Alex R. Lane, Claudine Wack, Alain C. Mita, Laurent Kassalow, Stephanie L. Barber, Jean François Dedieu, Andrea Wang-Gillam, Jennifer L. Moseley, Monica M. Mita, A. Craig Lockhart, John Sarantopoulos, Shankar Sundaram
Publikováno v:
Investigational New Drugs. 32:1236-1245
Introduction Cabazitaxel is a second-generation taxane with in vivo activity against taxane-sensitive and -resistant tumor cell lines and tumor xenografts. Cabazitaxel/cisplatin have therapeutic synergism in tumor-bearing mice, providing a rationale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7180585963ad6fbf190331d0d1323040
https://doi.org/10.1007/s10637-014-0145-y
https://doi.org/10.1007/s10637-014-0145-y
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Emmanuelle Vigne, Michel Perricaudet, Irene Mahfouz, Anne Brie, Patrice Yeh, Jean-François Dedieu
Publikováno v:
Journal of Virology. 73:5156-5161
Hypervariable region 5 (HVR5) is a hydrophilic, serotypically nonconserved loop of the hexon monomer which extrudes from the adenovirus (Ad) capsid. We have replaced the HVR5 sequence of Ad5 with that of heterologous peptides and studied their effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094f2c784159e7b02d302cc80ecc9587
https://doi.org/10.1128/jvi.73.6.5156-5161.1999
https://doi.org/10.1128/jvi.73.6.5156-5161.1999
Autor:
Dominique Croix, François Bernet, Isabelle Dutriez-Casteloot, Jean Lesage, Jean-Claude Beauvillain, Jean-Paul Dupouy, Jean-François Dedieu, Christine Laborie, Valérie Montel
Publikováno v:
Neuroscience Letters. 263:1-4
The present investigation concerns 80–90 day-old male rats born from morphine-exposed mothers (2×10 mg/kg per day from days 11 to 18 of gestation which showed at birth reduced size and activity of the adrenals). This prenatal treatment did not sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5d79ff17f12948e306676d0ba21f6f
https://doi.org/10.1016/s0304-3940(99)00086-5
https://doi.org/10.1016/s0304-3940(99)00086-5
Autor:
Jean-François Dedieu, Catherine Le Jossic, Nicolas Ferry, Michel Perricaudet, Marie-Pierre Bralet, Patrick B. Arbuthnot, Christian Bréchot
Publikováno v:
Human Gene Therapy. 7:1503-1514
Recombinant adenoviruses are widely used for the transfer of foreign genes into various mammalian cells. However, the utilization of these vectors for cancer gene therapy requires the specific and efficient expression of the transferred gene in tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9c488f8c6bc61ca6879bce15214333
https://doi.org/10.1089/hum.1996.7.13-1503
https://doi.org/10.1089/hum.1996.7.13-1503
Publikováno v:
Virology. 205:596-602
The Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) has been shown to transactivate both cellular and viral gene promoters including the promoter for the viral terminal protein 1 gene (TP-1). We investigated whether three other EBV nuclear antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f1adcbddb261d6654abe5ef384fbc0
https://doi.org/10.1006/viro.1994.1687
https://doi.org/10.1006/viro.1994.1687