Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Jean-François Decaux"'
1
Akademický článek
Generation of induced pluripotent stem cell line (TMOi001-A-11) carrying a homozygous deletion in the synemin gene using CRISPR/Cas9
Autor: Caterina Gargano, Jean-Sébastien Vartanian-Grimaldi, Yeranuhi Hovhannisyan, Pierre Joanne, Onnik Agbulut, Zhenlin Li, Ara Parlakian, Jean-François Decaux
Publikováno v: Stem Cell Research, Vol 73, Iss , Pp 103254- (2023)
A number of genetic variants in the SYNM gene encoding for the intermediate filament synemin have been reported in patients with cardiomyopathies, skeletal myopathies, cancer and certain neurodegenerative disorders. To better understand its role, we
Externí odkaz: https://doaj.org/article/9404622fd46048358d4d347e69fbc742
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2
Akademický článek
Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction
Autor: Melissa Touvron, Brigitte Escoubet, Mathias Mericskay, Aude Angelini, Luciane Lamotte, Maria Paola Santini, Nadia Rosenthal, Dominique Daegelen, David Tuil, Jean-François Decaux
Publikováno v: Disease Models & Mechanisms, Vol 5, Iss 4, Pp 481-491 (2012)
SUMMARY Cardiac fibrosis is critically involved in the adverse remodeling accompanying dilated cardiomyopathies (DCMs), which leads to cardiac dysfunction and heart failure (HF). Connective tissue growth factor (CTGF), a profibrotic cytokine, plays a
Externí odkaz: https://doaj.org/article/026dec2ca08d4b0f90d20e21db6d26a1
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3
Akademický článek
Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a Axis.
Autor: Aude Angelini, Zhenlin Li, Mathias Mericskay, Jean-François Decaux
Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0139858 (2015)
Myocardial fibrosis contributes to the remodeling of heart and the loss of cardiac function leading to heart failure. SRF is a transcription factor implicated in the regulation of a large variety of genes involved in cardiac structure and function. T
Externí odkaz: https://doaj.org/article/beeb039c4d8b4d488b75e71a7f85edab
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6
Interrelation between α-Cardiac Actin Treadmilling and Myocardin-Related Transcription Factor-A Nuclear Shuttling in Cardiomyocytes
Autor: Mark-Alexander Gorey, Mathias Mericskay, Zhenlin Li, Jean-François Decaux
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2022, 23 (13), pp.7394. ⟨10.3390/ijms23137394⟩
International Journal of Molecular Sciences, 2022, 23 (13), pp.7394. ⟨10.3390/ijms23137394⟩
International audience; Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics that are controlled by Rho GTPases. SRF is a ubiquitous transcription factor strongly expresse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d590354a5bac90935b09f71e2b6b85f
https://doi.org/10.3390/ijms23137394
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7
Srf controls satellite cell fusion through the maintenance of actin architecture
Autor: Ulduz Faradova, Laura Collard, Stéphane Vassilopoulos, Emilie Schol, Jean François Decaux, Alessandra Pincini, Aikaterini Papaefthymiou, Athanassia Sotiropoulos, Chiara Noviello, Voahangy Randrianarison-Huetz, Pascal Maire, Gaëlle Herledan
Publikováno v: Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (2), pp.685-700. ⟨10.1083/jcb.201705130⟩
The Journal of Cell Biology
Journal of Cell Biology, 2018, 217 (2), pp.685-700. ⟨10.1083/jcb.201705130⟩
This work describes a crucial role for the transcription factor Srf and F-actin scaffold to drive muscle stem cell fusion in vitro and in vivo and provides evidence of how actin cytoskeleton architecture affects myoblast fusion in vertebrates.
S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff832032dc77c16077073c35ef05cfb
https://hal.archives-ouvertes.fr/hal-02397529
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8
Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy
Autor: Joffrey Zoll, Jean-François Decaux, Mathias Mericskay, Marie Breton, Anne Garnier, Boris Manoury, Mélanie Gressette, Cynthia Tannous, Jérôme Piquereau, Charles Brenner, Nicolas Diguet, István Baczkó, Samuel A.J. Trammell, Jocelyne Blanc, Zhenlin Li, Anne Gouge, Nathalie Mougenot, Gareth G. Lavery, Robin Deloux
Publikováno v: Circulation
Circulation, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩
Circulation, American Heart Association, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩
Background: Myocardial metabolic impairment is a major feature in chronic heart failure. As the major coenzyme in fuel oxidation and oxidative phosphorylation and a substrate for enzymes signaling energy stress and oxidative stress response, nicotina
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff8c9d79a5527d8a72b3544c248b40d
https://pubmed.ncbi.nlm.nih.gov/29784693
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9
Inactivation of serum response factor contributes to decrease vascular muscular tone and arterial stiffness in mice
Autor: Guillaume Galmiche, Mathias Mericskay, Robert Feil, Dario Coletti, Kevin Retailleau, Jocelyne Blanc, Jean François Decaux, Zhenlin Li, Véronique Regnault, Mustapha Bourhim, Patrick Lacolley, Laurent Loufrani, Jacqueline Gao-Li, Pascal Challande, Daniel Henrion, Karima Ait Aissa, Carlos Labat
Publikováno v: Circulation Research
Circulation Research, American Heart Association, 2013, 112 (7), pp.1035-U149. ⟨10.1161/CIRCRESAHA.113.301076⟩
Circulation Research, American Heart Association, 2013, 112 (7), pp.1035-1045. ⟨10.1161/CIRCRESAHA.113.301076⟩
Circulation Research, 2013, 112 (7), pp.1035-U149. ⟨10.1161/CIRCRESAHA.113.301076⟩
Rationale: Vascular smooth muscle (SM) cell phenotypic modulation plays an important role in arterial stiffening associated with aging. Serum response factor (SRF) is a major transcription factor regulating SM genes involved in maintenance of the con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397043151edcbc7c923b90ef71902985
https://pubmed.ncbi.nlm.nih.gov/23426017
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10
Cloning and Characterization of the Mouse Glucokinase Gene Locus and Identification of Distal Liver-Specific DNase I Hypersensitive Sites
Autor: Jean-François Decaux, Daryl K. Granner, Kathy D. Shelton, Jean Girard, Cathleen C. Pettepher, Ramine Parsa, Kevin D. Niswender, Catherine Postic, Mark A. Magnuson, Betty Gouhot
Publikováno v: Genomics
Genomics, Elsevier, 1995, 29 (3), pp.740-750. ⟨10.1006/geno.1995.9943⟩
Genomics, 1995, 29 (3), pp.740-750. ⟨10.1006/geno.1995.9943⟩
We cloned and characterized an 83-kb fragment of mouse genomic DNA containing the entire glucokinase (GK) gene. The 11 exons of the gene span a total distance of 49 kb, with exons 1{beta} and 1L being separated by 35 kb. A total of 25,266 bp of DNA s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e9f54910d46231cacf4b70a6f19a53
https://doi.org/10.1006/geno.1995.9943
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