Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jean-François Cotte"'
Autor:
Camille Malburet, Michel Martin, Laurent Leclercq, Jean-François Cotte, Jérôme Thiebaud, Jean-Philippe Biron, Joseph Chamieh, Hervé Cottet
Publikováno v:
Talanta Open, Vol 7, Iss , Pp 100209- (2023)
The development of a new vaccine requires the precise characterization of all the physicochemical parameters of the vaccine antigens, which are the molecules that induce the immune response. Taylor dispersion analysis (TDA) is a promising alternative
Externí odkaz:
https://doaj.org/article/1883aa58a52a46bf92607f5e7900d3bf
Autor:
Camille Malburet, Laurent Leclercq, Jean-François Cotte, Jérôme Thiebaud, Emilie Bazin, Marie Garinot, Hervé Cottet
Publikováno v:
Analytical Chemistry. 94:4677-4685
Messenger RNA vaccines have come into the spotlight as a promising and adaptive alternative to conventional vaccine approaches. The efficacy of mRNA vaccines relies on the ability of mRNA to reach the cytoplasm of cells, where it can be translated in
Autor:
Jérôme Thiebaud, Jean-François Cotte, Laurent Leclercq, Hervé Cottet, Sergio Marco, Marie-Claire Nicolaï, Camille Malburet
Publikováno v:
Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2021, 93 (16), pp.6508-6515. ⟨10.1021/acs.analchem.1c00420⟩
Analytical Chemistry, 2021, 93 (16), pp.6508-6515. ⟨10.1021/acs.analchem.1c00420⟩
Analytical Chemistry, American Chemical Society, 2021, 93 (16), pp.6508-6515. ⟨10.1021/acs.analchem.1c00420⟩
Analytical Chemistry, 2021, 93 (16), pp.6508-6515. ⟨10.1021/acs.analchem.1c00420⟩
International audience; Vaccine adjuvants are immunostimulatory substances used to improve and modulate the immune response induced by antigens. A better understanding of the antigen-adjuvant interactions is necessary to develop future effective vacc
Autor:
Camille Malburet, Laurent Leclercq, Jean-François Cotte, Jérôme Thiebaud, Emilie Bazin, Marie Garinot, Hervé Cottet
Publikováno v:
Gene therapy.
Lipid nanoparticles (LNPs) are currently the most advanced non-viral clinically approved messenger ribonucleic acid (mRNA) delivery systems. The ability of a mRNA vaccine to have a therapeutic effect is related to the capacity of LNPs to deliver the
Publikováno v:
Journal of chromatography. A. 1667
The development of combination vaccines is essential to reduce the number of injections, shorten vaccination schedules and increase vaccination coverage. Vaccine adjuvants are used to modulate and enhance the immune response induced by the antigens.
Publikováno v:
Biomacromolecules
Biomacromolecules, American Chemical Society, 2020, 21 (8), pp.3364-3373. ⟨10.1021/acs.biomac.0c00782⟩
Biomacromolecules, American Chemical Society, In press, ⟨10.1021/acs.biomac.0c00782⟩
Biomacromolecules, American Chemical Society, 2020, 21 (8), pp.3364-3373. ⟨10.1021/acs.biomac.0c00782⟩
Biomacromolecules, American Chemical Society, In press, ⟨10.1021/acs.biomac.0c00782⟩
International audience; Vaccine adjuvants are used to enhance the immune response induced by antigens that have insufficient immunostimulatory capabilities. The present work aims at developing a frontal analysis continuous capillary electrophoresis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd07f0b878363d504fe7b94f7159c47c
https://hal.archives-ouvertes.fr/hal-03019683/document
https://hal.archives-ouvertes.fr/hal-03019683/document
Autor:
Jean-François Cotte, Philippe Talaga, Véronique Chambon, Isabelle Jaudinaud, Agathe Sordoillet, Afifa Bouadam
Publikováno v:
Analytical and Bioanalytical Chemistry. 409:2083-2092
Synthetic polyelectrolytes are a broad class of vaccine adjuvants. Among them, polyacrylic acid (PAA), a polyanionic polymer, is currently evaluated by Sanofi Pasteur. As chain length is considered to be a critical quality attribute for adjuvant prop
Autor:
François Dalençon, Nicolas Burdin, Véronique Chambon, Fabienne Piras, Shehzad M. Iqbal, Jean-François Cotte, Jean Haensler, Patricia Probeck, Lynn D. Hawkins, Jin Su
Publikováno v:
International journal of pharmaceutics. 486(1-2)
We describe the development, analytical characterization, stability and preclinical efficacy of AF04, a combination adjuvant comprising the synthetic toll-like receptor 4 (TLR4) agonist, E6020, formulated in AF03, a thermoreversible squalene emulsion
Autor:
Cotte, Jean-François1 jean-francois.cotte@sanofipasteur.com, Bouadam, Afifa1, Sordoillet, Agathe1, Jaudinaud, Isabelle1, Chambon, Véronique1, Talaga, Philippe1
Publikováno v:
Analytical & Bioanalytical Chemistry. Mar2017, Vol. 409 Issue 8, p2083-2092. 10p.