Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jean-François Cloix"'
Publikováno v:
Experimental Neurology. 225:274-283
Brain glycogen could be considered as an energy store for neuronal activity, with high relevance in epilepsies. We selected two lines of mice based upon their latency to methionine sulfoximine (MSO) dependent-seizures: MSO-Fast and MSO-Slow, and thei
Autor:
Julia S. Hartenstein, Michel Bernier, Chester R. Frazier, Irving W. Wainer, Jean-François Cloix, Mukesh Gandhari
Publikováno v:
Molecular and Cellular Endocrinology. 315:314-318
The purpose of this study was to examine expression and function of estrogen receptor-related receptors (ERRs) in human glioma and astrocytoma cell lines. These estrogen receptor-negative cell lines expressed ERRalpha and ERRgamma proteins to varying
Autor:
Jean-François Cloix, Tobias Hévor
Publikováno v:
Current Medicinal Chemistry
Seizures are the result of a sudden and temporary synchronization of neuronal activity, the reason for which is not clearly understood. Astrocytes participate in the control of neurotransmitter storage and neurotransmission efficacy. They provide fue
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 8:187-197
Glucose is the main fuel for cell life, and supports a number of different processes in providing cells with energy. Excess glucose is polymerized into glycogen, which is an energy-glucose store. Alterations in glycogen content and/or synthesis have
Autor:
Katy Bernard-Hélary, Maryvonne Ardourel, Pierre J. Magistretti, Tobias Hévor, Jean-François Cloix
Publikováno v:
Glia. 37:379-382
In order to assess the participation of astrocytic gluconeogenesis in the synthesis of glycogen, mouse astrocytes were stably transfected with antisense cDNA of fructose-1,6-bisphosphatase (FBPase) and with sense and antisense cDNAs of glycogen synth
Publikováno v:
Pharmaceutical Research. 19:104-107
Publikováno v:
Toxicology. 153:179-187
Methionine sulfoximine is a xenobiotic amino acid derived from methionine. One of its major properties is to display a glycogenic activity in the brain. After studying this property, we investigate here a possible action of this xenobiotic on the exp
Publikováno v:
NeuroReport. 8:617-622
THE mouse fructose-1,6-bisphosphatase (FBPase) cDNA was previously cloned from testicular teratocarcinoma cultured cells (F9 cells). Using this published nucleotide sequence four primer sets were defined and used to amplify FBPase transcript from cer
Autor:
Anuradha Ramamoorthy, Irving W. Wainer, Katina Sourou Sylvestre Dossou, Ruin Moaddel, Michel Bernier, Jean-François Cloix, Rajib K. Paul, Artur Wnorowski, Arnaud Paris
Publikováno v:
Pharmacology Research & Perspectives
(R,R’)-4-methoxy-1-naphthylfenoterol (MNF) inhibits cancer cell proliferation in vitro through cell-type specific modulation of β2-adrenergic receptor and/or cannabinoid receptor function. Here, we report an investigation into antitumor activity o
Publikováno v:
Epilepsy research. 104(3)
The experimental model of seizures which depends upon methionine sulfoximine (MSO) simulates the most striking form of human epilepsy. MSO generates epileptiform seizures in a large variety of animals, increases brain glycogen content and induces bra