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of 6
pro vyhledávání: '"Jean-Enno Charton"'
Autor:
Sarah J. Becker, André T. Nemat, Simon Lucas, René M. Heinitz, Manfred Klevesath, Jean Enno Charton
Publikováno v:
AI & SOCIETY.
The rapid and dynamic nature of digital transformation challenges companies that wish to develop and deploy novel digital technologies. Like other actors faced with this transformation, companies need to find robust ways to ethically guide their inno
Publikováno v:
Veröffentlichungen des Instituts für Deutsches, Europäisches und Internationales Medizinrecht, Gesundheitsrecht und Bioethik der Universitäten Heidelberg und Mannheim ISBN: 9783662590515
Das CRISPR/Cas9-System hat die Biotechnologie revolutioniert und ermoglicht Eingriffe in das Genom mit zuvor nicht fur moglich gehaltener Effizienz. Merck bietet als Wissenschafts- und Technologiekonzern eine breite Palette von Produkten und Dienstle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0439f40896e88687daf5ad532a1fea
https://doi.org/10.1007/978-3-662-59052-2_4
https://doi.org/10.1007/978-3-662-59052-2_4
Autor:
Georg Lenz, Christiane Pelzer, Montserrat Guzzardi, Chantal Décaillet, Bernd Dörken, Margot Thome, Stephan Hailfinger, Maike Jaworski, Peter Lenz, Jean-Enno Charton, Hendrik Nogai, Michael Grau, Katrin Cabalzar
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14596-14601
The protease activity of the paracaspase Malt1 contributes to antigen receptor-mediated lymphocyte activation and lymphomagenesis. Malt1 activity is required for optimal NF-κB activation, but little is known about the responsible substrate(s). Here
Autor:
Alexander Wacker, Hans-Georg Rammensee, Benjamin J Schmiedel, Frank Grünebach, Helmut R. Salih, Jean Enno Charton, Tina Baessler, Matthias Krusch
Publikováno v:
Blood. 115:3058-3069
Natural killer (NK) cells play an important role in the immunosurveillance of leukemia. Their reactivity is governed by a balance of activating and inhibitory receptors including various members of the tumor necrosis factor receptor (TNFR) family. He
Publikováno v:
Cold Spring Harbor Perspectives in Biology. 2:a003004-a003004
The signaling pathway controlling antigen receptor-induced regulation of the transcription factor NF-kappaB plays a key role in lymphocyte activation and development and the generation of lymphomas. Work of the past decade has led to dramatic progres
Autor:
Frank Gruenebach, Tina Baessler, Corina Buechele, Jean Enno Charton, Benjamin J Schmiedel, Alexander Wacker, Matthias Krusch, Helmut R. Salih, Lothar Kanz
Publikováno v:
Blood. 114:279-279
Abstract 279 In mouse models, stimulation of the TNF receptor family member 4-1BB/CD137 on cytotoxic lymphocytes by agonistic antibodies potently stimulated anti-tumor immunity, which has led to the development of humanized agonistic 4-1BB mAb that a