Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jean-Denys Hamel"'
Autor:
Jean-Denys Hamel, Jean-François Paquin
Publikováno v:
Journal of Fluorine Chemistry. 216:11-23
The intramolecular hydroalkoxylation of gem-difluorinated alkynols was found possible under Au catalysis, allowing for the preparation of a series of fluorinated heterocycles. The nature of the solvent was found to be especially critical in the cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a876b6dbe865e4178fc9796d990c4b06
https://doi.org/10.1016/j.jfluchem.2018.09.009
https://doi.org/10.1016/j.jfluchem.2018.09.009
Publikováno v:
Synthesis. 50:881-955
Monofluoroalkenes have found wide application in organic chemistry, medicinal chemistry, and materials science. This review summarizes the most recent advances made regarding the preparation of monofluoroalkenes, covering the period between October 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb019fd9e4fa07b611daaaf42e3da568
https://doi.org/10.1055/s-0036-1591867
https://doi.org/10.1055/s-0036-1591867
Autor:
Jean-Denys Hamel, Jean-François Paquin
Publikováno v:
Chemical Communications. 54:10224-10239
C-F bond activation has drawn a lot of attention in the past, and the case of C(sp3)-F bonds is particularly interesting as those are the strongest single bonds carbon makes with any other element. This Feature Article aims at highlighting our work a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05dd5438ec0643cbecff415b2b80f80
https://doi.org/10.1039/c8cc05108a
https://doi.org/10.1039/c8cc05108a
Publikováno v:
Synlett. 28:2823-2828
We report that aromatic propargylation is achievable with secondary propargylic fluorides, thus affording 1-alkyl-1-aryl-2-alkynes. In the present case, hydrogen bonding is responsible for the activation of the C–F bond. A large excess of arene nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743a49744d32309b0c52405937c83931
https://doi.org/10.1055/s-0036-1589057
https://doi.org/10.1055/s-0036-1589057
Autor:
Olivier Thibeault, Jean-Denys Hamel, Meggan Beaudoin, Jean-François Paquin, Paul R. Savoie, Mélissa Cloutier, Tatsuru Hayashi
Publikováno v:
Organic & Biomolecular Chemistry. 15:9830-9836
Herein, we report a highly regioselective gold-catalyzed formal hydration of propargylic gem-difluorides. Not only does this transformation provide access to versatile fluorinated building blocks that were difficult or hardly possible to access befor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8205c363e0908317f92b698004a8e4
https://doi.org/10.1039/c7ob02406a
https://doi.org/10.1039/c7ob02406a
Publikováno v:
Synlett. 27:821-830
In this account, we summarize our work on the synthesis of monofluoroalkenes starting from difluoropropenes. 1 Introduction 2 Metal-Catalyzed Transformations of 3,3-Difluoropropenes 2.1 Palladium Catalysis 2.2 Platinum Catalysis 3 Metal-Free Reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64364f5d6ed64c110bdc3adf57c9f610
https://doi.org/10.1055/s-0035-1560550
https://doi.org/10.1055/s-0035-1560550
Publikováno v:
Journal of Fluorine Chemistry. 174:81-87
The synthesis of monofluoroalkenes using a Pt-catalyzed amination reaction of cyclic 3,3-difluoropropenes is reported. The use of secondary aliphatic amines and cyclic 3,3-difluoropropenes is necessary for the success of the reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1dcbbddc11743b09d63eee343cf9a7d
https://doi.org/10.1016/j.jfluchem.2014.07.012
https://doi.org/10.1016/j.jfluchem.2014.07.012
Autor:
Mathilde Vandamme, Jean Denys Hamel, Pier Alexandre Champagne, Jean-François Paquin, Justine Desroches
Publikováno v:
Chemical Reviews. 115:9073-9174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1d5393f832cda20ff9d57d7813d329
https://doi.org/10.1021/cr500706a
https://doi.org/10.1021/cr500706a
Publikováno v:
Chemistry - A European Journal. 19:8751-8754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901aa7bb984433672c8817a395f771ac
https://doi.org/10.1002/chem.201300992
https://doi.org/10.1002/chem.201300992
Publikováno v:
ChemInform. 47
The superior nucleofuge character of chlorine over fluorine was taken advantage of in the selective SN2′ substitution reaction of gem-chlorofluoropropenes, allowing for the clean formation of β-substituted monofluoroalkenes under metal-free condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd805981129eea1b9a54eeaa74ae312
https://doi.org/10.1002/chin.201634094
https://doi.org/10.1002/chin.201634094