Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jean-Denis Franssen"'
Autor:
Valérie Wittamer, Patricia de Nadai, Maryse Brait, Jean-Denis Franssen, Benjamin Bondue, Olivier De Henau, François Huaux, Laurie Rouger, Marc Parmentier, Souphalone Luangsay
Publikováno v:
The Journal of Immunology. 183:6489-6499
Chemerin is the ligand of the ChemR23 receptor and a chemoattractant factor for human immature dendritic cells (DCs), macrophages, and NK cells. In this study, we characterized the mouse chemerin/ChemR23 system in terms of pharmacology, structure-fun
Autor:
Francesca Gentili, William Vermi, Jean-Denis Franssen, Silvano Sozzani, Fabio Facchetti, Luisa Massardi, Elena Riboldi, Marc Parmentier, Simona Marrelli, Annunciata Vecchi, Alberto Mantovani, Valérie Wittamer, Marina Sironi, Walter Luini, David Communi
Publikováno v:
The Journal of Experimental Medicine
Chemerin is a chemotactic agent that was recently identified as the ligand of ChemR23, a serpentine receptor expressed by activated macrophages and monocyte-derived dendritic cells (DCs). This paper shows that blood plasmacytoid and myeloid DCs expre
Autor:
Nathalie Clement, Thierry Velu, Karim El Bakkouri, Siew Chiat Cheong, Jean-Denis Franssen, Charlotte Servais, Anne-Nicole Brandenburger
Publikováno v:
The Journal of Gene Medicine. 7:189-197
Background The natural oncotropism and oncotoxicity of vectors derived from the autonomous parvovirus, minute virus of mice (prototype strain) [MVM(p)], combined with the immunotherapeutic properties of cytokine transgenes, make them interesting cand
Autor:
Alberto Mantovani, Marisa Vulcano, Cédric Blanpain, Gilbert Vassart, Isabelle Migeotte, Valérie Wittamer, David Communi, Jean-Denis Franssen, Stéphane Brézillon, Silvano Sozzani, Jean François Mirjolet, Marc Parmentier, Richard Tyldesley, Michel Detheux, Emmanuel Le Poul
Publikováno v:
The Journal of Experimental Medicine, 198 (7
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Dendritic cells (DCs) and macrophages are professional antigen-presenting cells (APCs) that play key roles in both innate and adaptive immunity. ChemR23 is an orphan G protein-coupled receptor related to chemokine receptors, which is expressed specif
Autor:
Jean Lucchetti, Emmanuel Le Poul, Vincent Dupriez, Stéphane Brézillon, Michel Detheux, Jean-Denis Franssen, Marc Parmentier, Vincent Lannoy
Publikováno v:
Journal of Biological Chemistry. 278:776-783
GPR7 and GPR8 are two structurally related orphan G protein-coupled receptors, presenting high similarities with opioid and somatostatin receptors. Two peptides, L8 and L8C, derived from a larger precursor, were recently described as natural ligands
Publikováno v:
European Journal of Immunology. 32:494-501
Human chemokine receptor (HCR) is a putative chemokine receptor sharing high similarity with CCR1, CCR2, CCR3 and CCR5. Its gene is located within the main cluster of CC-chemokine receptor genes, in the 3p21 region of the human genome. We generated m
Autor:
Jean-Denis Franssen, Wolf H. Fridman, Jean-Luc Teillaud, Agnès Coronel, Jean-Loup Romet-Lemonne, Aurélie Boyer
Publikováno v:
British Journal of Haematology. 114:671-680
Clinical grade ex vivo-generated antigen-presenting cells, macrophage–dendritic cells (MAC–DCs) or macrophage-activated killers (MAKs) were derived from peripheral blood mononuclear cells (PBMCs). Cultures (7 d) were performed in non-adherent con
Autor:
Aude Guillabert, Marc Parmentier, Thalie Devosse, Nicky D'Haene, Alix Berton, Jean-Denis Franssen, Silvano Sozzani, Isabelle Salmon, Patricia de Nadai, Sophie Noel, Maryse Brait
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(8)
The formyl peptide receptor (FPR) is a key player in innate immunity and host defense mechanisms. In humans and other primates, a cluster of genes encodes two related receptors, FPR-like 1 and FPR-like 2 (FPRL1 and FPRL2). Despite their high sequence
Autor:
Roberta Daniele, Ornella De Pità, Claudia Scarponi, Paola Fortugno, Safiyè Gonzalvo-Feo, Stefania Madonna, Marc Parmentier, Sabatino Pallotta, Jean-Denis Franssen, Silvano Sozzani, Giampiero Girolomoni, Cristina Albanesi, Daniela Bosisio
Publikováno v:
The Journal of experimental medicine, 206 (1
Journal of Experimental Medicine; Vol 206
The Journal of Experimental Medicine
Journal of Experimental Medicine; Vol 206
The Journal of Experimental Medicine
Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of plasmacytoid dendritic cells (pDC) into the skin. The molecules involved in pDC accumulation in psoriasis lesions are unknown. Chemerin is the only in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385b592e1216bca1362e6ad027821b85
http://hdl.handle.net/11379/28462
http://hdl.handle.net/11379/28462
Autor:
Thierry Velu, Richard G. Vile, Anne-Nicole Brandenburger, Siew Chiat Cheong, Catherine Bruyns, Jean-Denis Franssen, Myrto Trakatelli, Vy A. Phan, Isabelle Blangenois, Charlotte Servais
Publikováno v:
The journal of gene medicine. 8(7)
Background Hybrids obtained by fusion between tumour cells (TC) and dendritic cells (DC) have been proposed as anti-tumour vaccines because of their potential to combine the expression of tumour-associated antigens with efficient antigen presentation