Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Jean-Daniel Zucker"'
Autor:
Nihar Ranjan Dash, Mohammad T. Al Bataineh, Rohia Alili, Habiba Al Safar, Noura Alkhayyal, Edi Prifti, Jean-Daniel Zucker, Eugeni Belda, Karine Clément
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The gut microbiome plays a significant role in the development of Type 2 Diabetes Mellitus (T2DM), but the functional mechanisms behind this association merit deeper investigation. Here, we used the nanopore sequencing technology for metagen
Externí odkaz:
https://doaj.org/article/9a526ce46bae4b2e90c182375525f374
Autor:
Petros Andrikopoulos, Judith Aron-Wisnewsky, Rima Chakaroun, Antonis Myridakis, Sofia K. Forslund, Trine Nielsen, Solia Adriouch, Bridget Holmes, Julien Chilloux, Sara Vieira-Silva, Gwen Falony, Joe-Elie Salem, Fabrizio Andreelli, Eugeni Belda, Julius Kieswich, Kanta Chechi, Francesc Puig-Castellvi, Mickael Chevalier, Emmanuelle Le Chatelier, Michael T. Olanipekun, Lesley Hoyles, Renato Alves, Gerard Helft, Richard Isnard, Lars Køber, Luis Pedro Coelho, Christine Rouault, Dominique Gauguier, Jens Peter Gøtze, Edi Prifti, Philippe Froguel, The MetaCardis Consortium, Jean-Daniel Zucker, Fredrik Bäckhed, Henrik Vestergaard, Torben Hansen, Jean-Michel Oppert, Matthias Blüher, Jens Nielsen, Jeroen Raes, Peer Bork, Muhammad M. Yaqoob, Michael Stumvoll, Oluf Pedersen, S. Dusko Ehrlich, Karine Clément, Marc-Emmanuel Dumas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The host-microbiota co-metabolite trimethylamine N-oxide (TMAO) is linked to increased cardiovascular risk but how its circulating levels are regulated remains unclear. We applied “explainable” machine learning, univariate, multivariate
Externí odkaz:
https://doaj.org/article/12ff1d1de8474b4894451345fa26b4ed
Autor:
Vincent Martenot, Valentin Masdeu, Jean Cupe, Faustine Gehin, Margot Blanchon, Julien Dauriat, Alexander Horst, Michael Renaudin, Philippe Girard, Jean-Daniel Zucker
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Introduction Detecting safety signals attributed to a drug in scientific literature is a fundamental issue in pharmacovigilance. The constant increase in the volume of publications requires the automation of this tedious task, in order to fi
Externí odkaz:
https://doaj.org/article/e77bc466270f4498a9df7b2c803ce673
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2023)
The exploration of heath data by clustering algorithms allows to better describe the populations of interest by seeking the sub-profiles that compose it. This therefore reinforces medical knowledge, whether it is about a disease or a targeted populat
Externí odkaz:
https://doaj.org/article/a62d6552534d443cb8b280cc864d478f
Autor:
Jean Debédat, Tiphaine Le Roy, Lise Voland, Eugeni Belda, Rohia Alili, Solia Adriouch, Pierre Bel Lassen, Kazuyuki Kasahara, Evan Hutchison, Laurent Genser, Licia Torres, Camille Gamblin, Christine Rouault, Jean-Daniel Zucker, Nathalie Kapel, Christine Poitou, Geneviève Marcelin, Federico E. Rey, Judith Aron-Wisnewsky, Karine Clément
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Roux-en-Y gastric bypass (RYGB) is efficient at inducing drastic albeit variable weight loss and type-2 diabetes (T2D) improvements in patients with severe obesity and T2D. We hypothesized a causal implication of the gut microbiota (GM) in these meta
Externí odkaz:
https://doaj.org/article/654258ef9e724ebcac21d473da8919a3
Autor:
Pierre Bel Lassen, Eugeni Belda, Edi Prifti, Maria Carlota Dao, Florian Specque, Corneliu Henegar, Laure Rinaldi, Xuedan Wang, Sean P. Kennedy, Jean-Daniel Zucker, Wim Calame, Benoît Lamarche, Sandrine P. Claus, Karine Clément
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Interactions between diet and gut microbiota are critical regulators of energy metabolism. The effects of fibre intake have been deeply studied but little is known about the impact of proteins. Here, we investigated the effects of high prote
Externí odkaz:
https://doaj.org/article/60260b2442fa442b9a8a5900f4157062
Autor:
Antonio Molinaro, Pierre Bel Lassen, Marcus Henricsson, Hao Wu, Solia Adriouch, Eugeni Belda, Rima Chakaroun, Trine Nielsen, Per-Olof Bergh, Christine Rouault, Sébastien André, Florian Marquet, Fabrizio Andreelli, Joe-Elie Salem, Karen Assmann, Jean-Philippe Bastard, Sofia Forslund, Emmanuelle Le Chatelier, Gwen Falony, Nicolas Pons, Edi Prifti, Benoit Quinquis, Hugo Roume, Sara Vieira-Silva, Tue H. Hansen, Helle Krogh Pedersen, Christian Lewinter, Nadja B. Sønderskov, The MetaCardis Consortium, Lars Køber, Henrik Vestergaard, Torben Hansen, Jean-Daniel Zucker, Pilar Galan, Marc-Emmanuel Dumas, Jeroen Raes, Jean-Michel Oppert, Ivica Letunic, Jens Nielsen, Peer Bork, S. Dusko Ehrlich, Michael Stumvoll, Oluf Pedersen, Judith Aron-Wisnewsky, Karine Clément, Fredrik Bäckhed
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Gut microbial metabolism of nutrients contributes to metabolic diseases, and the histidine metabolite imidazole propionate (ImP) is produced by type 2 diabetes (T2D) associated microbiome. Here the authors report that circulating ImP levels are incre
Externí odkaz:
https://doaj.org/article/bdbb435b4d944496b157432e614c287b
Publikováno v:
Data & Policy, Vol 3 (2021)
Like a hydra, fraudsters adapt and circumvent increasingly sophisticated barriers erected by public or private institutions. Among these institutions, banks must quickly take measures to avoid losses while guaranteeing the satisfaction of law-abiding
Externí odkaz:
https://doaj.org/article/b6355ac9260c4d7888d7d1311f9051cf
Publikováno v:
Frontiers in Artificial Intelligence, Vol 3 (2020)
Addressing the heterogeneity of both the outcome of a disease and the treatment response to an intervention is a mandatory pathway for regulatory approval of medicines. In randomized clinical trials (RCTs), confirmatory subgroup analyses focus on the
Externí odkaz:
https://doaj.org/article/982c860058074d70bbda100902874b72
Autor:
Matthias Van Hul, Tiphaine Le Roy, Edi Prifti, Maria Carlota Dao, Adrien Paquot, Jean-Daniel Zucker, Nathalie M. Delzenne, Giulio G. Muccioli, Karine Clément, Patrice D. Cani
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Gut microbes are considered as major factors contributing to human health. Nowadays, the vast majority of the data available in the literature are mostly exhibiting negative or positive correlations between specific bacteria and metabolic parameters.
Externí odkaz:
https://doaj.org/article/7d927de099cb424184afa9c113c6821b