Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Jean-Claude Weill"'
Autor:
Clara Cousu, Eléonore Mulot, Annie De Smet, Sara Formichetti, Damiana Lecoeuche, Jianke Ren, Kathrin Muegge, Matthieu Boulard, Jean-Claude Weill, Claude-Agnès Reynaud, Sébastien Storck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract HELLS/LSH (Helicase, Lymphoid Specific) is a SNF2-like chromatin remodelling protein involved in DNA methylation. Its loss-of-function in humans causes humoral immunodeficiency, called ICF4 syndrome (Immunodeficiency, Centromeric Instability
Externí odkaz:
https://doaj.org/article/6f039c8a6d20420db31703b546655057
Autor:
Eva-Maria Cox, Mohamed El-Behi, Stefanie Ries, Johannes F. Vogt, Vivien Kohlhaas, Thomas Michna, Benoît Manfroi, Mona Al-Maarri, Florian Wanke, Boaz Tirosh, Corinne Pondarre, Harry Lezeau, Nir Yogev, Romy Mittenzwei, Marc Descatoire, Sandra Weller, Jean-Claude Weill, Claude-Agnès Reynaud, Pierre Boudinot, Luc Jouneau, Stefan Tenzer, Ute Distler, Anne Rensing-Ehl, Christoph König, Julian Staniek, Marta Rizzi, Aude Magérus, Frederic Rieux-Laucat, F. Thomas Wunderlich, Nadine Hövelmeyer, Simon Fillatreau
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112378- (2023)
Summary: The signals controlling marginal zone (MZ) and follicular (FO) B cell development remain incompletely understood. Here, we show that AKT orchestrates MZ B cell formation in mice and humans. Genetic models that increase AKT signaling in B cel
Externí odkaz:
https://doaj.org/article/92cc14fd0e5540159395986a3869f5d7
Autor:
Viviana Valeri, Akhésa Sochon, Clara Cousu, Pascal Chappert, Damiana Lecoeuche, Pascal Blanc, Jean-Claude Weill, Claude-Agnès Reynaud
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2022)
ÍSince the introduction of new generation pertussis vaccines, resurgence of pertussis has been observed in many developed countries. Former whole-cell pertussis (wP) vaccines are able to protect against disease and transmission but have been replace
Externí odkaz:
https://doaj.org/article/f572597211b04b79bd410d6d366a552a
Autor:
Viviana Valeri, Akhésa Sochon, Chaoliang Ye, Xinru Mao, Damiana Lecoeuche, Simon Fillatreau, Jean-Claude Weill, Claude-Agnès Reynaud, Yi Hao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
MBCs (MBCs) generated in T-dependent immune responses can persist for a lifetime and rapidly react upon secondary antigen exposure to differentiate into plasma cells (PCs) and/or to improve the affinity of their BCR through new rounds of hypermutatio
Externí odkaz:
https://doaj.org/article/544d1cda87624ca69cda57852d018a9c
Autor:
Matthieu Mahévas, Imane Azzaoui, Etienne Crickx, Florence Canoui-Poitrine, Delphine Gobert, Laetitia Languille, Nicolas Limal, Constance Guillaud, Laure Croisille, Mohamed Jeljeli, Fréderic Batteux, Samia Baloul, Olivier Fain, France Pirenne, Jean-Claude Weill, Claude-Agnès Reynaud, Bertrand Godeau, Marc Michel
Publikováno v:
Haematologica, Vol 106, Iss 9 (2020)
B-cell activating factor may be involved in the failure of B-cell depleting therapy with rituximab in immune thrombocytopenia (ITP) by promoting the emergence of splenic long-lived plasma cells. From results obtained in mouse models, we hypothesized
Externí odkaz:
https://doaj.org/article/2ac29e68217d4438b55eecdece153773
Autor:
Bénédict Fallet, Yi Hao, Marianna Florova, Karen Cornille, Alba Verge de los Aires, Giulia Girelli Zubani, Yusuf I. Ertuna, Victor Greiff, Ulrike Menzel, Karim Hammad, Doron Merkler, Sai T. Reddy, Jean-Claude Weill, Claude-Agnès Reynaud, Daniel D. Pinschewer
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1013-1026.e7 (2020)
Summary: Persistent viral infections subvert key elements of adaptive immunity. To compare germinal center (GC) B cell responses in chronic and acute lymphocytic choriomeningitis virus infection, we exploit activation-induced deaminase (AID) fate-rep
Externí odkaz:
https://doaj.org/article/1e1d8fe3acfc47169da56f38415abc28
Autor:
Aurélien Sokal, Paul Bastard, Pascal Chappert, Giovanna Barba-Spaeth, Slim Fourati, Alexis Vanderberghe, Pauline Lagouge-Roussey, Isabelle Meyts, Adrian Gervais, Magali Bouvier-Alias, Imane Azzaoui, Ignacio Fernández, Andréa de la Selle, Qian Zhang, Lucy Bizien, Isabelle Pellier, Agnès Linglart, Anya Rothenbuhler, Estelle Marcoux, Raphael Anxionnat, Nathalie Cheikh, Juliane Léger, Blanca Amador-Borrero, Fanny Fouyssac, Vanessa Menut, Jean-Christophe Goffard, Caroline Storey, Caroline Demily, Coralie Mallebranche, Jesus Troya, Aurora Pujol, Marie Zins, Pierre Tiberghien, Paul E. Gray, Peter McNaughton, Anna Sullivan, Jane Peake, Romain Levy, Laetitia Languille, Carlos Rodiguez-Gallego, Bertrand Boisson, Sébastien Gallien, Bénédicte Neven, Marc Michel, Bertrand Godeau, Laurent Abel, Felix A. Rey, Jean-Claude Weill, Claude-Agnès Reynaud, Stuart G. Tangye, Jean-Laurent Casanova, Matthieu Mahévas
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2023, 220 (1), pp.e20220258. ⟨10.1084/jem.20220258⟩
Journal of Experimental Medicine, Rockefeller University Press, 2023, 220 (1), pp.e20220258. ⟨10.1084/jem.20220258⟩
Journal of Experimental Medicine, 2023, 220 (1), pp.e20220258. ⟨10.1084/jem.20220258⟩
Journal of Experimental Medicine, Rockefeller University Press, 2023, 220 (1), pp.e20220258. ⟨10.1084/jem.20220258⟩
Inborn and acquired deficits of type I interferon (IFN) immunity predispose to life-threatening COVID-19 pneumonia. We longitudinally profiled the B cell response to mRNA vaccination in SARS-CoV-2 naive patients with inherited TLR7, IRF7, or IFNAR1 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4c643b10eefe470305c6fddfdaebcc
https://hal-pasteur.archives-ouvertes.fr/pasteur-03847416/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03847416/document
Autor:
Etienne Crickx, Selda Aydin, Alexandre Karras, Farah Tamirou, Jean-Claude Weill, Aurélie Hummel, Ailsa Robbins, Claude-Agnès Reynaud, Tatiana Fadeev, Frédéric Houssiau, Bernard Lauwerys, Tessa Huscenot, Nathalie Costedoat-Chalumeau, Matthieu Mahévas, Marion Rabant, Philippe Remy, Véronique Le Guern
Publikováno v:
Arthritis & rheumatology, Vol. 73, no. 8, p. 1461-1466 (2021)
OBJECTIVE: This study was undertaken to characterize kidney and urine antibody-secreting cells (ASCs) from patients with active lupus nephritis, before and after induction therapy. METHODS: We included patients with biopsy-proven active lupus nephrit
Autor:
Pascal Chappert, François Huetz, Marie-Alix Espinasse, Fabrice Chatonnet, Louise Pannetier, Lucie Da Silva, Clara Goetz, Jérôme Megret, Aurélien Sokal, Etienne Crickx, Ivan Nemazanyy, Vincent Jung, Chiara Guerrera, Sébastien Storck, Matthieu Mahévas, Antonio Cosma, Patrick Revy, Thierry Fest, Claude-Agnès Reynaud, Jean-Claude Weill
Publikováno v:
SSRN Electronic Journal.
Autor:
Aurélien Sokal, Matteo Broketa, Giovanna Barba-Spaeth, Annalisa Meola, Ignacio Fernández, Slim Fourati, Imane Azzaoui, Andrea de La Selle, Alexis Vandenberghe, Anais Roeser, Magali Bouvier-Alias, Etienne Crickx, Laetitia Languille, Marc Michel, Bertrand Godeau, Sébastien Gallien, Giovanna Melica, Yann Nguyen, Virginie Zarrouk, Florence Canoui-Poitrine, France Noizat-Pirenne, Jérôme Megret, Jean-Michel Pawlotsky, Simon Fillatreau, Etienne Simon-Lorière, Jean-Claude Weill, Claude-Agnès Reynaud, Félix A. Rey, Pierre Bruhns, Pascal Chappert, Matthieu Mahévas
Publikováno v:
Immunity
Immunity, Elsevier, In press, ⟨10.1016/j.immuni.2022.04.002⟩
Immunity, 2022, 55 (6), pp.1096-1104.e4. ⟨10.1016/j.immuni.2022.04.002⟩
Immunity, Elsevier, In press, ⟨10.1016/j.immuni.2022.04.002⟩
Immunity, 2022, 55 (6), pp.1096-1104.e4. ⟨10.1016/j.immuni.2022.04.002⟩
International audience; The SARS-CoV-2 Omicron variant can escape neutralization by vaccine-elicited and convalescent antibodies. Memory B cells (MBCs) represent another layer of protection against SARS-CoV-2, as they persist after infection and vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79edd55453451c697a1469c536ca195
https://hal.archives-ouvertes.fr/hal-03652602/file/1-s2.0-S107476132200173X-main.pdf
https://hal.archives-ouvertes.fr/hal-03652602/file/1-s2.0-S107476132200173X-main.pdf