Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jean-Claude Sulpice"'
Autor:
Chantal Melchior, Oliver Nüße, Maud Delattre, Eric Tschirhart, Sophie Dupré-Crochet, Marie Cécile Faure, Magali Prigent, Marc Lavielle, Marie-Hélène Cuif, Jean-Claude Sulpice
Publikováno v:
Biology of the Cell. 105:501-518
Background information: During phagocytosis, neutrophils internalize pathogens in a phagosome and produce reactive oxygen species (ROS) by the NADPH oxidase to kill the pathogen. The cytosolic NADPH oxidase subunits p40phox, p47phox, p67phox and Rac2
Publikováno v:
Biochemical Pharmacology. 80:1012-1020
During brain or cardiac ischemia/reperfusion neutrophils are recruited and activated contributing to inflammation and tissue damage. Neutrophils are removed from inflamed tissues by phosphatidylserine-dependent phagocytosis. Production of reactive ox
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1761:195-204
Platelet membrane phosphatidylserine (PS) exposure that regulates the production of thrombin represents an important link between platelet activation and the coagulation cascade. Here, we have evaluated the involvement of the Na+/H+ exchanger (NHE) i
Publikováno v:
Journal of Biological Chemistry. 279:21815-21823
Extracellular ATP (ATP(ec)), a possible effector in thymocyte selection, induces thymocyte death via purinoceptor activation. We show that ATP(ec) induced cell death by apoptosis, rather than lysis, and early phosphatidylserine (PS) exposure and phos
Autor:
Françoise Giraud, Pierre Maziere, Sandrine Lépine, Jean-Claude Sulpice, Boris Lakatoš, Marie-Pierre Courageot
Publikováno v:
Annals of the New York Academy of Sciences. 973:190-193
It is generally accepted that ceramide plays an essential role in apoptosis. In this study we suggest that in thymocytes, dexamethasone-induced apoptosis is mediated by sphingosine rather than ceramide, through the activation of an aSMase and a ceras
Publikováno v:
Annals of the New York Academy of Sciences. 973:186-189
The present study shows for the first time that ATP(ec) induces a very early PS exposure in thymocytes and that this process can be induced in the absence of Ca(2+) influx and caspase activation.
Publikováno v:
Biochemistry. 40:15752-15761
During platelet activation, phosphatidylserine (PS) exposure on the extracellular face of the plasma membrane is associated with increased procoagulant activity. PS externalization is generally attributed to an increase in intracellular Ca(2+). Vario
Autor:
Marie Cécile, Faure, Jean-Claude, Sulpice, Maud, Delattre, Marc, Lavielle, Magali, Prigent, Marie-Hélène, Cuif, Chantal, Melchior, Eric, Tschirhart, Oliver, Nüße, Sophie, Dupré-Crochet
Publikováno v:
Biology of the cell. 105(11)
During phagocytosis, neutrophils internalise pathogens in a phagosome and produce reactive oxygen species (ROS) by the NADPH oxidase to kill the pathogen. The cytosolic NADPH oxidase subunits p40(phox), p47(phox), p67(phox) and Rac2 translocate to th
Publikováno v:
Journal of Molecular and Cellular Cardiology. 25:973-982
The kinetics and signal transduction of inositol phosphate production were studied after a 20% stretch of neonatal rat cardiomyocytes in culture. Inositol trisphosphate (IP3) production was increased by 41% above control after 10-20s of cellular stre
Asymmetric distribution of phosphoinositides and phosphatidic acid in the human erythrocyte membrane
Autor:
Françoise Giraud, Michel Claret, Jean-Claude Sulpice, Monique Sauvage, Philippe Gascard, Kiyoko Fukami, Dien Tran, Tadaomi Takenawa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1069:27-36
The distribution of phosphoinositides and phosphatidic acid (PA) between the outer and inner layers of the human erythrocyte membrane was investigated by using two complementary methodologies: hydrolysis by phospholipase A2 (PLA2) and immunofluoresce