Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Jean-Claude Rossi"'
Autor:
Chiara Chiabrando, Claudia Rivalta, Renzo Bagnati, Anna Valagussa, Thierry Durand, Alexandre Guy, Pia Villa, Jean-Claude Rossi, Roberto Fanelli
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 3, Pp 495-509 (2002)
F2-isoprostanes (F2-iPs) are prostaglandin (PG)-like products of non-enzymatic free radical-catalyzed peroxidation of arachidonic acid that are now widely used as indices of lipid peroxidation in vivo. Knowledge of the metabolic fate of F2-iPs in viv
Externí odkaz:
https://doaj.org/article/85245440c3384f0c9c13b8ea4a34c101
Autor:
Jean-Claude Rossi, Emilie Mas, Patrick Chardon, Yoan Falquet, Valérie Bultel, Françoise Michel, Alexandre Guy, Thierry Durand, Jean-Paul Cristol
Publikováno v:
Journal of Chromatography B. 872:133-140
Isoprostanes are a family of prostaglandin isomers produced from oxidation of polyunsaturated fatty acids through a non-enzymatic free radical-catalyzed mechanism. Quantification of F2-isoprostanes (F2-IsoPs) provides a good index of oxidative stress
Publikováno v:
The Journal of Organic Chemistry. 70:989-997
Syntheses of the enantiomerically pure phytoprostanes B(1) type I and II are described starting from furfural and n-propylfuran. Key steps include the preparation of the Freimanis (+/-)-hydroxycyclopentenone and Wittig coupling using chiral phosphoni
Autor:
Jean-Louis Banères, Jean-Pierre Girard, Pierre Hullot, Joseph Parello, Jean-Claude Rossi, Aimée Martin
Publikováno v:
Journal of Molecular Biology. 329:801-814
We produced the human leukotriene B(4) (LTB(4)) receptor BLT1, a G-protein-coupled receptor, in Escherichia coli with yields that are sufficient for the first structural characterization of this receptor in solution. Overexpression was achieved throu
Autor:
Alexandre Guy, Thierry Durand, Olivier Henry, Jean-Pierre Vidal, Arlene Roland, Jean-Claude Rossi
Publikováno v:
Tetrahedron. 59:2485-2495
Radical cyclization of acyclic 1-substituted-2,4-dihydroxylated 5-hexenyl radicals produced functionalized cyclopentane derivatives. These cyclopentanic precursors after different protection/deprotection reactions followed by Wittig and Horner–Wads
Publikováno v:
The Journal of Organic Chemistry. 67:3615-3624
We report a new route to F(2t)-IsoP (formerly named 8-epi-PGF(2alpha)) using a biomimetic radical cyclization of a highly functionalized C20 precursor. The strategy employed gives a beta-hydroxy free radical followed by molecular oxygen trapping, whi
Autor:
Jean-Claude Rossi, Thierry Durand, Stéphanie Marlière, Jean-Luc Cracowski, Germain Bessard, Alexandre Guy, Françoise Stanke-Labesque, Janine Bessard, Olivier Chavanon
Publikováno v:
British Journal of Pharmacology. 135:1276-1280
Among the F2-isoprostanes, the 15- and the 5-series are currently used as markers of lipid peroxidation in vascular diseases. 15-F2t-IsoP (also named iPF2α-III) exerts a vasoconstriction in most vessels, whereas no data is available concerning 5-F2t
Publikováno v:
Tetrahedron Letters. 42:4333-4336
The first synthesis of two main urinary tetranor metabolites of 15-F2t-isoprostane methyl ester is described using l -glucose as starting material.
Autor:
Thierry Durand, Chiara Chiabrando, Anna Valagussa, Olivier Henry, Jean-Pierre Vidal, Jean-Claude Rossi, Alexandre Guy, Claudia Rivalta
Publikováno v:
European Journal of Organic Chemistry. 2001:809-819
Total syntheses are described of the methyl esters of enantiomers of two major urinary metabolites of 15F2t-isoprostane − 2,3-dinor-5,6-dihydro-15F2t-isoprostane 1 and 2,3-dinor-15F2t-isoprostane 2 − together with other, related, putative metabol
Autor:
Frank-Mathias Gutzki, Thierry Durand, Jürgen C. Frölich, Edzard Schwedhelm, Dimitrios Tsikas, Jean-Claude Rossi, Alexandre Guy
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 744:99-112
Whole body synthesis of F2-isoprostanes, a family of cyclooxygenase-independent eicosanoids formed by free-radical catalysed peroxidation, should be best assessed by quantifying their urinary metabolites. Two methods for the quantitative determinatio