Výsledky vyhledávání - "Jean-Claude Levron"

Pharmacokinetics of Itraconazole Oral Solution in Neutropenic Children during Long-Term Prophylaxis

Autor: Jean-Pierre le Moing, Jean-Claude Levron, Claudine Schmitt, Elisabeth Chwetzoff, Sophie Lemerle, Yves Perel, Jean-luc Harousseau

Publikováno v: Antimicrobial Agents and Chemotherapy. 45:1561-1564

We investigated the pharmacokinetics and safety of an oral solution of itraconazole in two groups of neutropenic children stratified by age. Effective concentrations of itraconazole in plasma were reached quickly and maintained throughout treatment.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc56aabe601a05b891d82730e252a53a
https://doi.org/10.1128/aac.45.5.1561-1564.2001

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Risperidone Drug Monitoring

Autor: Pascal Odou, C. Brunet, M. Luyckx, H. Robert, Jean-Claude Levron

Publikováno v: Clinical Drug Investigation. 19:283-292

Background: Risperidone is an atypical antipsychotic drug that has been marketed in France since 1996. Therapeutic failures have been observed with risperidone. Objective: To investigate whether interactions with the cytochrome P450 (CYP) isoenzymes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47cf4aab8e624296d4e94ccac9be550e
https://doi.org/10.2165/00044011-200019040-00006

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Cardiac Baroreflex during the Postoperative Period in Patients with Hypertension

Autor: Pierre Sagnard, Jean Marie Cottet-Emard, G. Annat, Luc Quintin, Francis Bonnet, Joel L. Parlow, J. P. Viale, Marco Ghignone, Gerard Begou, Jean Claude Levron, Richard L. Hughson

Publikováno v: Anesthesiology. 90:681-692

Background Patients with essential hypertension show altered baroreflex control of heart rate, and during the perioperative period they demonstrate increased circulatory instability. Clonidine has been shown to reduce perioperative circulatory instab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a692168d35e62aa1666b52fdbe500c8
https://doi.org/10.1097/00000542-199903000-00008

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Comparative Pharmacokinetic Study of Fentanyl and Sufentanil after Single High-Bolus Doses

Autor: D. Guilmet, A. Brusset, P. Olivier, Jean-Claude Levron, J.P. Le Moing, T. Guenoun, C. Dubois, M. Fischler, L. Valide, S. Schlumberger

Publikováno v: Clinical Drug Investigation. 18:377-389

Objective: To investigate and compare the pharmacokinetic parameters of sufentanil and fentanyl during a prolonged period after single bolus administration, and to detect and compare the occurrence of secondary peaks of opioid plasma concentration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f484bde23359adf671b9493893f99e74
https://doi.org/10.2165/00044011-199918050-00005

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Clonidine for Major Vascular Surgery in Hypertensive Patients

Autor: J. R. Brudon, T. Danays, C. Boucaud, M. Ghignone, Jean-Claude Levron, B. Frehring, Sylvie Tissot, Luc Quintin, J. P. Viale, X. Bouilloc, M. C. Bayon, P. Petit, H. Tassan, E. Butin

Publikováno v: Anesthesia & Analgesia. 83:687-695

The utility of clonidine for hypertensive patients presenting for major vascular procedures remains debatable. Twenty-one hypertensive patients presenting for aortic surgery were given clonidine (n = 11) or placebo (n = 10) in a double-blind, randomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afd43ae43b1c3a30107eebaa3dbd137
https://doi.org/10.1097/00000539-199610000-00005

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Long-term itraconazole prophylaxis against Aspergillus infections in thirty-two patients with chronic granulomatous disease

Autor: Jean Donadieu, Richard Mouy, Raja Brauner, Jean-Claude Levron, Claude Griscelli, Stéphane Blanche, Alain Fischer, Florence Veber

Publikováno v: The Journal of Pediatrics. 125:998-1003

We conducted a prospective, open study of oral itraconazole therapy (5 and then 10 mg/kg per day) to assess tolerance and potential efficacy in preventing fungal infections in patients with chronic granulomatous disease. Thirty-two patients were enro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0c67b5ee364c27cd7c0d3643ae8fa6
https://doi.org/10.1016/s0022-3476(05)82023-2

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Correlation of clinical response (PANSS) and plasma levels of haloperidol and reduced haloperidol in schizophrenia

Autor: Jean-Claude Levron, Edvick Elia, Francoise Erb, Daniel Sechter, Michele Jacquet, Jean Pommery, Jean-Marc Leroux, Philippe Bouhours

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 18:347-353

1. The authors attempted to correlate plasma concentrations in H/rH and clinical efficacy from 8 schizophrenic patients (DSM III R ) on H. 2. No significant correlations were found between H, rH plasma levels and positive and negative subscale for ea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7ae42b16fd651c707e8931b5ef7fa3
https://doi.org/10.1016/0278-5846(94)90066-3

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Determination of risperidone and 9-hydroxyrisperidone in human plasma by high-performance liquid chromatography with electrochemical detection

Autor: Jean-Claude Levron, S. Edouard, J.P. Le Moing

Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 614:333-339

A method for the determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma has been developed. The procedure involved a multi-step liquid—liquid extraction with an internal standard. The parent drug and its metabol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd7c6ea516e8c99e5938e6cfe99ea08
https://doi.org/10.1016/0378-4347(93)80327-z

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