Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jean-Claude Jeanny"'
Autor:
Pierre-Raphaël Rothschild, Sawsen Salah, Marianne Berdugo, Emmanuelle Gélizé, Kimberley Delaunay, Marie-Christine Naud, Christophe Klein, Alexandre Moulin, Michèle Savoldelli, Ciara Bergin, Jean-Claude Jeanny, Laurent Jonet, Yvan Arsenijevic, Francine Behar-Cohen, Patricia Crisanti
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. Rho-associated kinase (ROCK), an effector of the small GTPase Rho, involved in cytoskeleton d
Externí odkaz:
https://doaj.org/article/8758b404d405418ca43ea07240fbe4ea
Autor:
Marina G. Yefimova, Nadia Messaddeq, Alice Karam, Carine Jacquard, Chantal Weber, Laurent Jonet, Uwe Wolfrum, Jean-Claude Jeanny, Yvon Trottier
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 1, Pp 311-324 (2010)
In neurodegenerative disorders caused by polyglutamine (polyQ) expansion, polyQ toxicity is thought to trigger a linear cascade of successive degenerative events leading to neuronal death. To understand how neurons cope with polyQ toxicity, we studie
Externí odkaz:
https://doaj.org/article/6edc4f3a318f4c6587fb525b143f74f3
Autor:
Laura Kowalczuk, Elodie Touchard, Samy Omri, Laurent Jonet, Christophe Klein, Fatemeh Valamanes, Marianne Berdugo, Pascal Bigey, Pascale Massin, Jean-Claude Jeanny, Francine Behar-Cohen
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17462 (2011)
There are controversies regarding the pro-angiogenic activity of placental growth factor (PGF) in diabetic retinopathy (DR). For a better understanding of its role on the retina, we have evaluated the effect of a sustained PGF over-expression in rat
Externí odkaz:
https://doaj.org/article/5b1ae9299bb54e1ab5e5bac6eb2a9ee3
Autor:
Marianne Houssier, William Raoul, Sophie Lavalette, Nicole Keller, Xavier Guillonneau, Barbara Baragatti, Laurent Jonet, Jean-Claude Jeanny, Francine Behar-Cohen, Flavio Coceani, Daniel Scherman, Pierre Lachapelle, Huy Ong, Sylvain Chemtob, Florian Sennlaub
Publikováno v:
PLoS Medicine, Vol 5, Iss 2, p e39 (2008)
BACKGROUND: In the Western world, a major cause of blindness is age-related macular degeneration (AMD). Recent research in angiogenesis has furthered the understanding of choroidal neovascularization, which occurs in the "wet" form of AMD. In contras
Externí odkaz:
https://doaj.org/article/294d600092c349c3b76b3fe387d7bf39
Autor:
Claire Gozalo, Laurent Jonet, Francine Behar-Cohen, Patricia Crisanti, Michèle Savoldelli, Zoubir Djerada, Elsa Kermorvant-Duchemin, Emilie Picard, Jacques Beltrand, Alexandre Moulin, Jean-Claude Jeanny, Alejandra Daruich, Justine Guegan, Lolita Radet, Kimberley Delaunay, Michel Polak, Marie-Christine Naud, Marianne Berdugo
Publikováno v:
Translational Research. 229:83-99
Sulfonylureas, widely used as hypoglycemic agents in adults with type 2 diabetes, have neuroprotective effects in preclinical models of central nervous system injury, and in children with neuropsychomotor impairments linked to neonatal diabetes secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2e5bf716f1a43d38a71847a77e2ae6
https://doi.org/10.1016/j.trsl.2020.10.003
https://doi.org/10.1016/j.trsl.2020.10.003
Autor:
Claudine Versaux-Botteri, Julie Monnin, Deborah Chemouni, Sofiane Miloudi, F. Valamanesh, Jean-Claude Jeanny, Murhaf Zaher, Nadège Morand-Villeneuve, Germaine Michel
Publikováno v:
Experimental Eye Research. 110:26-34
Nestin is found in radial glia and neuronal/glial progenitor cells during retinal development, and is re-expressed after acute damage in the retina of adult mammals. We have investigated nestin expression in the retina of the Royal College of Surgeon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08da77b46e63ebd98c040123381ba548
https://doi.org/10.1016/j.exer.2013.01.013
https://doi.org/10.1016/j.exer.2013.01.013
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 197:661-675
RESUME Le fer est un oligo-element necessaire au metabolisme cellulaire, mais en exces, il peut-etre toxique. Il peut generer des radicaux libres oxygenes par le biais de la reaction de Fenton. Son accumulation a ete mise en evidence dans la retine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a21789c9a337daf17c8d609456eeb83d
https://doi.org/10.1016/s0001-4079(19)31562-6
https://doi.org/10.1016/s0001-4079(19)31562-6
Autor:
Elodie Touchard, Marie-Christine Naud, Michèle Savoldelli, Jean-Claude Jeanny, Marianne Berdugo, Mohamed El Sanharawi, Francine Behar-Cohen, Pascal Bigey
Publikováno v:
Molecular Therapy. 20(8):1559-1570
Photoreceptors and retinal pigment epithelial cells (RPE) targeting remains challenging in ocular gene therapy. Viral gene transfer, the only method having reached clinical evaluation, still raises safety concerns when administered via subretinal inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461c59ffb98bff4cccf4faeaa4922340
Autor:
Michael Möller, Claudia Di Tommaso, Jean-Louis Bourges, Gregory Trubitsyn, Robert Gurny, Alicia Torriglia, Jean-Claude Jeanny, Francine Behar-Cohen, F. Valamanesh
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 81:257-264
Cornea transplantation is one of the most performed graft procedures worldwide with an impressive success rate of 90%. However, for "high-risk" patients with particular ocular diseases in addition to the required surgery, the success rate is drastica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43e969c89db2ce6c964ab8e551aa1e2
https://doi.org/10.1016/j.ejpb.2012.02.014
https://doi.org/10.1016/j.ejpb.2012.02.014
Autor:
Amena Saïed, Elodie Touchard, Jean-Claude Jeanny, Laura Kowalczuk, Marie-Christine Naud, Francine Behar-Cohen, Mohamed El Sanharawi, Michele Boudinet, Pascal Laugier
Publikováno v:
Ultrasound in Medicine & Biology. 37:1814-1827
This study aimed to assess application of ultrasound (US) combined with microbubbles (MB) to transfect the ciliary muscle of rat eyes. Reporter DNA plasmids encoding for Gaussia luciferase , β-galactosidase or the green fluorescent protein (GFP), al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1306c7987a4c476232fa3d880fce3203
https://doi.org/10.1016/j.ultrasmedbio.2011.07.010
https://doi.org/10.1016/j.ultrasmedbio.2011.07.010