Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jean-Claude Duché"'
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 190:935-947
RESUME L'HSA (human serum albumin) et l'AGP (alpha glycoprotein) sont les seules proteines plasmatiques capables de lier les medicaments par des sites specifiques avec une forte affinite. Elles limitent alors leur distribution et parfois leur elimina
Autor:
Bruno Housset, Christos Chouaid, Jean-Paul Tillement, K. Atassi, Isabelle Monnet, Claire Fuhrman, Jean-Claude Duché, I Abd Alsamad
Publikováno v:
Clinical Biochemistry
Clinical Biochemistry, Elsevier, 2000, 33 (5), pp.405-10
Clinical Biochemistry, 2000, 33 (5), pp.405-10
Clinical Biochemistry, Elsevier, 2000, 33 (5), pp.405-10
Clinical Biochemistry, 2000, 33 (5), pp.405-10
International audience; STUDY OBJECTIVE: The aim of the study was to assess diagnosis value of tumor markers for differential diagnosis between mesothelioma and other pleural tumors. DESIGN AND METHODS: Prospective study of 85 patients attending our
Autor:
Saïk Urien, Jean-Claude Duché, Jérôme Barré, Emmanuelle Malaurie, Nicolas Simon, Isabelle Monnet
Publikováno v:
Clinical Biochemistry. 33:197-202
Objectives: We have investigated the AAG and its genetic variants concentrations in plasma samples of 61 patients suffering from different types of cancers. Design and methods: The patients were shared out in three groups, breast, lung, and ovary can
Autor:
Olivier Combes, Jérôme Barré, Laurent Vernillet, Saïk Urien, Yves Archimbaud, Jean-Paul Tillement, Michael P. Marietta, Jean-Claude Duché
Publikováno v:
Investigational New Drugs. 18:1-5
The binding of CPT-11 and SN-38 to human plasma proteins was studied by ultrafiltration at 37 degrees C and pH 7.4. In plasma, CPT-11 was 66-60% bound in the range 100-4000 ng/ml and SN-38 was 94-96% bound in the range 50-200 ng/ml. At these concentr
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 715:103-109
Human alpha1-acid glycoprotein (AAG) exists as an heterogeneous population of two or three genetic variants (ORM1 F1 and/or S and ORM2 A) in the plasma of most individuals. The ORM1 and ORM2 variants have a separate genetic origin. AAG belongs to the
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 715:111-123
Human α 1 -acid glycoprotein (AAG), an acute-phase plasma protein, is heterogeneous in the native state and polymorphic in the desialylated state. The AAG heterogeneity is mainly explained by a variable glycan chain composition in its five glycosyla
Autor:
Anne-Marie Chauvet-Monges, Jean-Paul Tillement, Nicolas Simon, Philippe Brunet, Jérôme Barré, Philippe d'Athis, Bertrand Dussol, Dimitri Roumenov, E. Albengres, Jean-Claude Duché, Yvon Berland
Publikováno v:
British Journal of Clinical Pharmacology. 44:591-594
Aims In renal allograft recipients, trimetazidine (Vastarel® ) was proposed to be associated with the classic immunosuppressant treatments because it displays anti-ischaemic effects which may protect against cyclosporine A nephrotoxicity. The object
Autor:
Jean-Claude Duché, Framboise Hervé, Philippe d'Athis, Jérôme Barré, Jean-Paul Tillement, Catherine Marché
Publikováno v:
Pharmacogenetics. 6:403-415
Human alpha 1-acid glycoprotein (AAG), a plasma drug transport protein, has three main genetic variants, the A variant and the F1 and S variants, which are encoded by two different genes. The binding of disopyramide, methadone, dipyridamole, chlorpro
Publikováno v:
British Journal of Clinical Pharmacology. 36:241-249
1. Human alpha 1-acid glycoprotein (AAG), a plasma transport protein, has three main genetic variants. F1. S and A. Native commercial AAG (a mixture of almost equal proportions of these three variants) has been separated by chromatography into varian
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 615:47-57
Fractionation of the three main genetic variants (F1, S and A) of human α1-acid glycoprotein (AAG), in their native (sialylated) form, by chromatography on immobilized copper(II) affinity adsorbent was investigated. This chromatographic method had b