Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes

Autor: Sèyigbéna P. Déo-Gracias Berry, Yabo Josiane Honkpèhedji, Esther Ludwig, Saïdou Mahmoudou, Ulrich Fabien Prodjinotho, Rafiou Adamou, Odilon P. Nouatin, Bayode R. Adégbitè, Jean Claude Dejon-Agobe, Romuald Beh Mba, Moustapha Maloum, Anne Marie Mouima Nkoma, Jeannot Fréjus Zinsou, Adrian J. F. Luty, Meral Esen, Ayôla Akim Adégnika, Clarissa Prazeres da Costa

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract Poor birth outcomes in low- and middle income countries are associated with maternal vitamin D deficiency and chronic helminth infections. Here, we investigated whether maternal Schistosoma haematobium affects maternal or cord vitamin D stat

Externí odkaz: https://doaj.org/article/6bb17c4933f04848a88f15e24b97cd8e

Publisher Correction: Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes

Autor: Sèyigbéna P. Déo‑Gracias Berry, Yabo Josiane Honkpèhedji, Esther Ludwig, Saïdou Mahmoudou, Ulrich Fabien Prodjinotho, Rafiou Adamou, Odilon P. Nouatin, Bayode R. Adégbitè, Jean Claude Dejon‑Agobe, Romuald Beh Mba, Moustapha Maloum, Anne Marie Mouima Nkoma, Jeannot Fréjus Zinsou, Adrian J. F. Luty, Meral Esen, Ayôla Akim Adégnika, Clarissa Prazeres da Costa

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/20d1f5ec7f5847e3b35395e2a14fa648

Prospective, observational study to assess the performance of CAA measurement as a diagnostic tool for the detection of Schistosoma haematobium infections in pregnant women and their child in Lambaréné, Gabon: study protocol of the freeBILy clinical trial in Gabon

Autor: Yabo Josiane Honkpehedji, Ayôla Akim Adegnika, Jean Claude Dejon-Agobe, Jeannot Fréjus Zinsou, Romuald Beh Mba, Jacob Gerstenberg, Raphaël Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Tahinamandranto Rasamoelina, Elisa Sicuri, Norbert G. Schwarz, Paul L. A. M. Corstjens, Pytsje T. Hoekstra, Govert J. van Dam, Andrea Kreidenweiss, on behalf of the freeBILy Consortium

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)

Abstract Background Schistosoma antigen detection in urine is a valuable diagnostic approach for schistosomiasis control programmes because of the higher sensitivity compared to parasitological methods and preferred sampling of urine over stool. High

Externí odkaz: https://doaj.org/article/1c96f41edad241de9bef22e31b15d1e1

Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon

Autor: Frejus Jeannot Zinsou, David Diemert, Jeffrey M. Bethony, Simon P. Jochems, Martin P. Grobusch, Yabo Josiane Honkpehedji, Sophie De Vries, Maria Elena Bottazzi, Peter J. Hotez, Remko van Leeuwen, Peter G. Kremsner, Friederike Sonnet, Jean-Claude Dejon Agobe, Ayola A. Adegnika, Yoanne D. Mouwenda, Koen A. Stam, Lucja A. Labuda, Marguerite Massinga Loembe, Madeleine E. Betouke Ongwe, Maria Yazdanbakhsh

Publikováno v: PLOS NEGLECTED TROPICAL DISEASES, 15(10). PUBLIC LIBRARY SCIENCE
PLoS neglected tropical diseases, 15(10):e0009732. Public Library of Science
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)

Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390e10806d665a609765ae41f0dab673
http://www.scopus.com/inward/record.url?scp=85117549876&partnerID=8YFLogxK

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

Autor: Sodiomon B. Sirima, Benjamin Mordmüller, Paul Milligan, Ulysse Ateba Ngoa, Fred Kironde, Frank Atuguba, Alfred B. Tiono, Saadou Issifou, Mark Kaddumukasa, Oscar Bangre, Clare Flach, Michael Christiansen, Peter Bang, Roma Chilengi, Søren Jepsen, Peter G. Kremsner, Michael Theisen, Alphonse Ouédraogo, Désiré Kargougou, Issa Nébié, Siaka Débé, Amidou Diarra, Edith Bougouma, Aurore B. Hounkpatin, Ayola Akim Adegnika, Bertrand Lell, Fanny Joanny, Yabo Josiane Honkpehedji, Jean Claude Dejon Agobe, Meral Esen, Anthony Ajua, Victor Asoala, Thomas Anyorigiya, Nana Akosua Ansah, William Buwembo, Edison Mworozi, Musa Sekikubo, Ismaela Abubakar, Kalifa Bojang, Ramadhani Noor, Brenda Okech, Dawit A. Ejigu

Publikováno v: Vaccine. 34:4536-4542

GMZ2 is a recombinant protein malaria vaccine, comprising two blood-stage antigens of Plasmodium falciparum, glutamate-rich protein and merozoite surface protein 3. We assessed efficacy of GMZ2 in children in Burkina Faso, Gabon, Ghana and Uganda. :

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8ed0e1cb81658bf8f4a7d6c73322c1
https://doi.org/10.1016/j.vaccine.2016.07.041