Fluorescence Study of Lipid-based DNA Carriers Properties: Influence of Cationic Lipid Chemical Structure

Autor: Jean-Claude Clément, Mathieu Mével, Paul-Alain Jaffrès, Farouk Ayadi, Jean-Jacques Yaouanc, Damien Loizeau, Laure Burel-Deschamps, Philippe Giamarchi

Publikováno v: Journal of Fluorescence
Journal of Fluorescence, Springer Verlag, 2008, 18 (5), pp.835-841. ⟨10.1007/s10895-008-0312-7⟩

International audience; We report here a study on the physicochemical properties of cationic phospholipids liposomes used for lipoplex formulation and DNA transfer. The original cationic phospholipids synthesized in our laboratory are first presented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea31a197bb9213e5f7eb3c831df2bb0
https://doi.org/10.1007/s10895-008-0312-7

Study of complexation of mono N-alkylcyclen and mono N-alkylcyclam with hexacarbonyl metal M(CO)6 (M  Cr, Mo). Specific N1,N7-dissymetric dialkylation of cyclen

Autor: Henri Handel, Jean-Jacques Yaouanc, Hervé des Abbayes, I. Gardinier, Véronique Patinec, Jean-Claude Clément

Publikováno v: Inorganica Chimica Acta. 244:105-108

Complexation of mono N -alkylcyclen ( 1 ) and mono N -alkylcyclam ( 2 ) with M(CO) 6 (M  Cr, Mo) yields only one LM(CO) 3 complex, in which the tertiary amine is not coordinated to the metal. An attempted explanation for the N 1 ,N 7 -dialkylation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39bd0ca857d79483e7a040e6967f500a
https://doi.org/10.1016/0020-1693(95)04765-4

Cobalt catalysed carbonylation of reactive chlorides into esters by methyl formate without carbon monoxide and methanol added

Autor: Hervé des Abbayes, Jean-Claude Clément, Pascale Laurent, Fabienne Ramirez-Vega

Publikováno v: Journal of Molecular Catalysis A: Chemical. 96:15-20

Reactive chlorides ZCH 2 Cl (Z = C 6 H 5 , CH 3 OC(O), CN) are readily carbonylated into esters with methyl formate as the sole source of carbon monoxide and methanol, the tetracarbonyl cobaltate anion as the catalyst and sodium carbonate as the base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33cb88278565d12fd94cdb90d384e10b
https://doi.org/10.1016/1381-1169(94)00049-2

Cationic Phosphonolipids Containing Quaternary Phosphonium and Arsonium Groups for DNA Transfection with Good Efficiency and Low Cellular Toxicity**

Autor: Jean-Claude Clément, Jean-Jacques Yaouanc, Séverine Loisel, Virginie Floch, Erwann Guénin, Anne-Cécile Hervé, Hervé des Abbayes, Claude Férec

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2000, 39, pp.629--631. ⟨10.1002/(SICI)1521-3773(20000204)39:33.0.CO;2-K⟩

International audience; Replacing the ammonium polar head in cationic lipids 1 (A = N) by a phosphonium or an arsonium group (A=P, As) improves their properties as synthetic vectors for DNA transfection. The increased volume of the cationic head is s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3ceae4f1e7c927cd231d935082e85c
https://doi.org/10.1002/(sici)1521-3773(20000204)39:3<629::aid-anie629>3.0.co

Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy

Autor: Tony Le Gall, Pierre Lehn, Chantal Pichon, Dominique Cartier, Pascal Delépine, Tristan Montier, Mathieu Mével, Patrick Midoux, Jean-Jacques Yaouanc, Paul-Alain Jaffrès, Claude Férec, Pascale Laurent, Jean-Claude Clément

Publikováno v: Phosphorus, Sulfur, and Silicon and the Related Elements
Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2008, 183 (2-3), pp.460-468. ⟨10.1080/10426500701761300⟩
Phosphorus, Sulfur, and Silicon and the Related Elements, 2008, 183 (2-3), pp.460-468. ⟨10.1080/10426500701761300⟩

International audience; Cationic lipids having a phosphorus group (phosphonate or phosphoramidate) to link the lipidic part to a cationic head form an efficient family of vectors for DNA delivery. The synthesis of these types of vectors is summarized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147f256e584d2297a06835b1d65030db
https://hal.univ-brest.fr/hal-01580434