Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jean-Claude Béïque"'
Publikováno v:
eLife, Vol 4 (2015)
Precise regulation of the dendritic spine actin cytoskeleton is critical for neurodevelopment and neuronal plasticity, but how neurons spatially control actin dynamics is not well defined. Here, we identify direct palmitoylation of the actin regulato
Externí odkaz:
https://doaj.org/article/c7022d31551d443baa7e24078413a5ba
Autor:
Emerson F Harkin, Michael B Lynn, Alexandre Payeur, Jean-François Boucher, Léa Caya-Bissonnette, Dominic Cyr, Chloe Stewart, André Longtin, Richard Naud, Jean-Claude Béïque
Publikováno v:
eLife, Vol 12 (2023)
By means of an expansive innervation, the serotonin (5-HT) neurons of the dorsal raphe nucleus (DRN) are positioned to enact coordinated modulation of circuits distributed across the entire brain in order to adaptively regulate behavior. Yet the netw
Externí odkaz:
https://doaj.org/article/20b69314e853484c8e8cab4b250de1de
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/f03973a8439b47959148b6b52af3b8f0
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100630- (2021)
Summary: Expansion microscopy is a sample preparation technique in which fixed and immunostained cells or tissues are embedded in a cross-linked network of swellable polyelectrolyte hydrogel that expands isotropically upon addition of deionized water
Externí odkaz:
https://doaj.org/article/34ee7600a962484dad3199d662412c36
Autor:
Timal S. Kannangara, Anthony Carter, Yingben Xue, Jagroop S. Dhaliwal, Jean-Claude Béïque, Diane C. Lagace
Publikováno v:
Stem Cell Reports, Vol 11, Iss 6, Pp 1327-1336 (2018)
Summary: Ischemic stroke enhances the proliferation of adult-generated precursor cells that ectopically migrate toward the infarct. Studies have correlated precursor cell proliferation and subsequent adult neurogenesis with enhanced stroke recovery,
Externí odkaz:
https://doaj.org/article/c73212abef8c4d01b37b01d54a696e56
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100176- (2020)
Summary: The proportion of silent (AMPAR-lacking) synapses is thought to be related to the plasticity potential of neural networks. We created a maximum-likelihood estimator of silent synapse fraction based on simulations of the underlying experiment
Externí odkaz:
https://doaj.org/article/fd99033d5fa946d1b2828de882ea9dad
Autor:
Ayden Gouveia, Matthew Seegobin, Timal S. Kannangara, Ling He, Fredric Wondisford, Cesar H. Comin, Luciano da F. Costa, Jean-Claude Béïque, Diane C. Lagace, Baptiste Lacoste, Jing Wang
Publikováno v:
Stem Cell Reports, Vol 9, Iss 6, Pp 1735-1744 (2017)
Summary: Epigenetic modifications have emerged as attractive molecular substrates that integrate extrinsic changes into the determination of cell identity. Since stroke-related brain damage releases micro-environmental cues, we examined the role of a
Externí odkaz:
https://doaj.org/article/a4ddc8595fdc48a483012399c66b060c
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1293-1303 (2017)
Summary: Hebbian and homeostatic forms of plasticity operate on different timescales to regulate synaptic strength. The degree of mechanistic overlap between these processes and their mutual influence are still incompletely understood. Here, we repor
Externí odkaz:
https://doaj.org/article/880d0978c37d45edbc1ee80904d351cf
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Properties of synaptic release dictates the core of information transfer in neural circuits. Despite decades of technical and theoretical advances, distinguishing bona fide information content from the multiple sources of synaptic variability remains
Externí odkaz:
https://doaj.org/article/39649b07614244ba95801b7526b2b5af
Autor:
Denise Cook, Erin Nuro, Emma V. Jones, Haider F. Altimimi, W. Todd Farmer, Valentina Gandin, Edith Hanna, Ruiting Zong, Alessandro Barbon, David L. Nelson, Ivan Topisirovic, Joseph Rochford, David Stellwagen, Jean-Claude Béïque, Keith K. Murai
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1402-1416 (2014)
Translational control of mRNAs allows for rapid and selective changes in synaptic protein expression that are required for long-lasting plasticity and memory formation in the brain. Fragile X Related Protein 1 (FXR1P) is an RNA-binding protein that c
Externí odkaz:
https://doaj.org/article/539896c5a668445d8f635b64d2926dcd