Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Jean-Christophe Paillart"'
Autor:
Jim Zoladek, Priscila El Kazzi, Vincent Caval, Valérie Vivet-Boudou, Marion Cannac, Emma L. Davies, Soléna Rossi, Inès Bribes, Lucile Rouilly, Yannick Simonin, Nolwenn Jouvenet, Etienne Decroly, Jean-Christophe Paillart, Sam J. Wilson, Sébastien Nisole
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Usutu virus (USUV) and West Nile virus (WNV) are two closely related emerging mosquito-borne flaviviruses. Their natural hosts are wild birds, but they can also cause severe neurological disorders in humans. Both viruses are efficiently supp
Externí odkaz:
https://doaj.org/article/3cb65610b3d540c1a7325f02e1ed92d7
Autor:
Layla Tajer, Jean-Christophe Paillart, Hanna Dib, Jean-Marc Sabatier, Ziad Fajloun, Ziad Abi Khattar
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1259 (2024)
Antimicrobial resistance (AMR) poses a serious global health concern, resulting in a significant number of deaths annually due to infections that are resistant to treatment. Amidst this crisis, antimicrobial peptides (AMPs) have emerged as promising
Externí odkaz:
https://doaj.org/article/7f061017385d41c682d1b09c7124a276
Autor:
Nam Nguyen Quang, Sophie Goudey, Emmanuel Ségéral, Ammara Mohammad, Sophie Lemoine, Corinne Blugeon, Margaux Versapuech, Jean-Christophe Paillart, Clarisse Berlioz-Torrent, Stéphane Emiliani, Sarah Gallois-Montbrun
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-24 (2020)
Abstract Background Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-1) replication that is tightly regulated both temporally and spatially. More than 50 different transcripts can be generated from a single HIV-1 unsplic
Externí odkaz:
https://doaj.org/article/ec999e0c1c3d4cb4a0f22e557b0c44ec
Autor:
Camille Libre, Tanja Seissler, Santiago Guerrero, Julien Batisse, Cédric Verriez, Benjamin Stupfler, Orian Gilmer, Romina Cabrera-Rodriguez, Melanie M. Weber, Agustin Valenzuela-Fernandez, Andrea Cimarelli, Lucie Etienne, Roland Marquet, Jean-Christophe Paillart
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 13 (2021)
The HIV-1 Vif protein is essential for viral fitness and pathogenicity. Vif decreases expression of cellular restriction factors APOBEC3G (A3G), A3F, A3D and A3H, which inhibit HIV-1 replication by inducing hypermutation during reverse transcription.
Externí odkaz:
https://doaj.org/article/b2309349bc6a44f39361b5cd5fb225d4
Autor:
Sébastien Lyonnais, S. Kashif Sadiq, Cristina Lorca-Oró, Laure Dufau, Sara Nieto-Marquez, Tuixent Escribà, Natalia Gabrielli, Xiao Tan, Mohamed Ouizougun-Oubari, Josephine Okoronkwo, Michèle Reboud-Ravaux, José Maria Gatell, Roland Marquet, Jean-Christophe Paillart, Andreas Meyerhans, Carine Tisné, Robert J. Gorelick, Gilles Mirambeau
Publikováno v:
Viruses, Vol 13, Iss 11, p 2312 (2021)
A growing number of studies indicate that mRNAs and long ncRNAs can affect protein populations by assembling dynamic ribonucleoprotein (RNP) granules. These phase-separated molecular ‘sponges’, stabilized by quinary (transient and weak) interacti
Externí odkaz:
https://doaj.org/article/35afacfa36b0410b8a99db77793c381e
Autor:
Orian Gilmer, Erwan Quignon, Anne-Caroline Jousset, Jean-Christophe Paillart, Roland Marquet, Valérie Vivet-Boudou
Publikováno v:
Viruses, Vol 13, Iss 10, p 1894 (2021)
RNA molecules are key players in a variety of biological events, and this is particularly true for viral RNAs. To better understand the replication of those pathogens and try to block them, special attention has been paid to the structure of their RN
Externí odkaz:
https://doaj.org/article/9328536c36fb4143b50f34e5faf17167
Publikováno v:
Viruses, Vol 13, Iss 8, p 1559 (2021)
Late assembly (L) domains are conserved sequences that are necessary for the late steps of viral replication, acting like cellular adaptors to engage the ESCRT membrane fission machinery that promote virion release. These short sequences, whose mutat
Externí odkaz:
https://doaj.org/article/4441270463b945a8b85c1612fd7eb2a4
Autor:
Benjamin Stupfler, Cédric Verriez, Sarah Gallois-Montbrun, Roland Marquet, Jean-Christophe Paillart
Publikováno v:
Viruses, Vol 13, Iss 4, p 617 (2021)
The ubiquitin–proteasome system plays an important role in the cell under normal physiological conditions but also during viral infections. Indeed, many auxiliary proteins from the (HIV-1) divert this system to its own advantage, notably to induce
Externí odkaz:
https://doaj.org/article/b35403e94d40487097841791f3a88f59
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2871 (2021)
Protein post-translational modifications (PTMs) play key roles in eukaryotes since they finely regulate numerous mechanisms used to diversify the protein functions and to modulate their signaling networks. Besides, these chemical modifications also t
Externí odkaz:
https://doaj.org/article/011ac2628f874b86abc61d6e3b263da4
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The genome of the retroviruses is a dimer composed by two homologous copies of genomic RNA (gRNA) molecules of positive polarity. The dimerization process allows two gRNA molecules to be non-covalently linked together through intermolecular base-pair
Externí odkaz:
https://doaj.org/article/2c54ace57d22462a8ee5e25af4b6d508