Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Jean-Christophe LEGA"'
Autor:
Alexiane Pradelle, Sabine Mainbourg, Steeve Provencher, Emmanuel Massy, Guillaume Grenet, Jean-Christophe Lega
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117353- (2024)
Externí odkaz:
https://doaj.org/article/4fb0ae46cc43446cb43b71fe16be51d8
Publikováno v:
European Respiratory Review, Vol 24, Iss 137, Pp 545-545 (2015)
Externí odkaz:
https://doaj.org/article/25f6d9d6f5cb46c1a06869c0a58390aa
Autor:
Alexiane PRADELLE, Sabine MAINBOURG, Steeve PROVENCHER, Emmanuel MASSY, Guillaume GRENET, Jean-Christophe LEGA
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116055- (2024)
Background: During the first wave of COVID-19, hydroxychloroquine (HCQ) was used off-label despite the absence of evidence documenting its clinical benefits. Since then, a meta-analysis of randomised trials showed that HCQ use was associated with an
Externí odkaz:
https://doaj.org/article/add263c9c8a84cae961bd1487eab1c63
Autor:
Yasmina Chouik, Fanny Lebossé, Marie-Laure Plissonnier, Jean-Christophe Lega, Pierre Pradat, Teresa Antonini, Miroslava Subic, Kerstin Hartig-Lavie, Domitille Erard, François Villeret, Céline Guichon, Audrey Payancé, Sylvie Radenne, Pierre-Emmanuel Rautou, Fabien Zoulim, Massimo Levrero
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107427- (2023)
Summary: Bacterial infections are the most frequent precipitating event in patients with acute decompensation of cirrhosis (AD) and are associated with high mortality. Early diagnosis is challenging due to cirrhosis-related systemic inflammation. Her
Externí odkaz:
https://doaj.org/article/681a2a68d7d84002818a7c1dd208e296
Autor:
Jean-Christophe Lega, Natalia Cabrera, Melanie Aureal, Milene Seauve, Soline Laplane, Fabienne Coury
Publikováno v:
RMD Open, Vol 9, Iss 3 (2023)
Objective To estimate the incidence of infections among patients with psoriatic arthritis (PsA) or axial spondyloarthritis (axSpA), two distinct phenotypes included in the large group of spondyloarthritis (SpA), treated with tumour necrosis-factor-in
Externí odkaz:
https://doaj.org/article/2cf3c9f5dd084897ba5838023e004684
Autor:
Yoann Roubertou, Sabine Mainbourg, Arnaud Hot, Denis Fouque, Cyrille Confavreux, Roland Chapurlat, Sébastien Debarbieux, Denis Jullien, Pascal Sève, Laurent Juillard, Marie-Nathalie Kolopp-Sarda, Jean-Christophe Lega
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Highlights • Cryoglobulinemia is frequent in SLE, but mostly asymptomatic. • Sixty-six percent of SLE patients tested positive for cryoglobulins, and 15% of the SLE patients with cryoglobulinemia developed a cryoglobulinemic vasculitis. • Featu
Externí odkaz:
https://doaj.org/article/526291c872104bcd9f39270ad8a9cd49
Autor:
Marion Douplat, Antoine Gavoille, Fabien Subtil, Julie Haesebaert, Laurent Jacquin, Guillaume Durand, Jean-Christophe Lega, Thomas Perpoint, Veronique Potinet, Julien Berthiller, Nathalie Perreton, Karim Tazarourte
Publikováno v:
Western Journal of Emergency Medicine, Vol 23, Iss 6 (2022)
Introduction: Few studies have investigated the management of COVID-19 cases from the operational perspective of the emergency department (ED), We sought to compare the management and outcome of COVID-19 positive and negative patients who presented t
Externí odkaz:
https://doaj.org/article/4d47202e3a584fa9b1e9cc37c86a76d2
Autor:
Roubi Kilo, Silvy Laporte, Rama Arab, Sabine Mainbourg, Steeve Provencher, Guillaume Grenet, Laurent Bertoletti, Laurent Villeneuve, Michel Cucherat, Jean-Christophe Lega, META-EMBOL Group
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract This study aimed to explore the validity of the use of the net clinical benefit (NCB), i.e. the sum of major bleeding and thrombotic events, as a potential surrogate for all-cause mortality in clinical trials assessing antithrombotics. Publi
Externí odkaz:
https://doaj.org/article/6ede1d7ffd7e45c089cbac448dc01abd
Autor:
Alexandre Belot
Publikováno v:
European Respiratory Review. 24:545.1-545
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3098eb8919e0add7ab6d5425a34c71d7
https://doi.org/10.1183/16000617.50002015
https://doi.org/10.1183/16000617.50002015
Autor:
Jérôme Hadjadj, Carla Noemi Castro, Maud Tusseau, Marie-Claude Stolzenberg, Fabienne Mazerolles, Nathalie Aladjidi, Martin Armstrong, Houman Ashrafian, Ioana Cutcutache, Georg Ebetsberger-Dachs, Katherine S. Elliott, Isabelle Durieu, Nicole Fabien, Mathieu Fusaro, Maximilian Heeg, Yohan Schmitt, Marc Bras, Julian C. Knight, Jean-Christophe Lega, Gaetan Lesca, Anne-Laure Mathieu, Marion Moreews, Baptiste Moreira, Audrey Nosbaum, Matthew Page, Cécile Picard, T. Ronan Leahy, Isabelle Rouvet, Ethel Ryan, Damien Sanlaville, Klaus Schwarz, Andrew Skelton, Jean-Francois Viallard, Sebastien Viel, Marine Villard, Isabelle Callebaut, Capucine Picard, Thierry Walzer, Stephan Ehl, Alain Fischer, Bénédicte Neven, Alexandre Belot, Frédéric Rieux-Laucat
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
SOCS1 is a potent suppressor of JAK-STAT signalling responses to IFNγ and γ-chain cytokines and thereby limits inflammation. Here the authors identify and characterize heterozygous SOCS1 mutations in 10 patients from 5 unrelated families with autoi
Externí odkaz:
https://doaj.org/article/e099b2415a024179917630ee4d4f2ec2