Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jean-Christophe Deschemin"'
Autor:
Jean-Christophe Deschemin, Céline Ransy, Frédéric Bouillaud, Soonkyu Chung, Bruno Galy, Carole Peyssonnaux, Sophie Vaulont
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The role of iron in the two major sites of adaptive thermogenesis, namely the beige inguinal (iWAT) and brown adipose tissues (BAT) has not been fully understood yet. Body iron levels and distribution is controlled by the iron regulatory pep
Externí odkaz:
https://doaj.org/article/000a1aee333f46febade769382d11b15
Autor:
Jean-Christophe Deschemin, Jacques R. R. Mathieu, Sara Zumerle, Carole Peyssonnaux, Sophie Vaulont
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Pulmonary iron excess is deleterious and contributes to a range of chronic and acute inflammatory diseases. Optimal lung iron concentration is maintained through dynamic regulation of iron transport and storage proteins. The iron-regulatory hormone h
Externí odkaz:
https://doaj.org/article/234f199df1134498b5f560dfe66194b6
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145685 (2015)
Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). Patients with CF suffer from chronic infections and severe inflammation
Externí odkaz:
https://doaj.org/article/3f96ed7cdc944cad8f4e1a6fc10f6ac1
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61050 (2013)
The anemia of chronic disease (also called anemia of inflammation) is an acquired disorder of iron homeostasis associated with infection, malignancy, organ failure, trauma, or other causes of inflammation. It is now widely accepted that induction of
Externí odkaz:
https://doaj.org/article/fd6bcf6c9fdf4ec6ba5b706ed9047c78
Autor:
Guillemette Ramey, Jean-Christophe Deschemin, Béatrice Durel, François Canonne-Hergaux, Gaël Nicolas, Sophie Vaulont
Publikováno v:
Haematologica, Vol 95, Iss 3 (2010)
Hepcidin, a circulating regulatory hormone peptide produced by hepatocytes, functions as the master regulator of cellular iron export by controlling the amount of ferroportin, an iron exporter present on the basolateral surface of intestinal enterocy
Externí odkaz:
https://doaj.org/article/ee6c1a9018754e4d86f4adf44479e33b
Publikováno v:
Haematologica, Vol 94, Iss 6 (2009)
Background The circulating hormone hepcidin plays a central role in iron homeostasis. Our goal was to establish an ex vivo iron-sensing model and to characterize the molecular mechanisms linking iron to hepcidin.Design and Methods Murine hepatocytes
Externí odkaz:
https://doaj.org/article/cc88af446f214eb7bc78939f45e994a6
Autor:
Romain Tortuyaux, Katia Avila‐Gutierrez, Marc Oudart, Noémie Mazaré, Philippe Mailly, Jean‐Christophe Deschemin, Sophie Vaulont, Carole Escartin, Martine Cohen‐Salmon
Publikováno v:
Journal of Neurochemistry. 164:847-857
Astrocytes are thought to play a crucial role in brain iron homeostasis. How they accomplish this regulation in vivo is unclear. In a recent transcriptomic analysis, we showed that polysomal Ftl1 and Fth1 mRNAs, encoding the ferritin light (Ftl) and
Autor:
Mélanie Gressette, Kaveen Bedouet, Jean-Christophe Deschemin, Valérie Domergue, Florence Lefebvre, Arnaud Bruneel, Sophie Vaulont, Mathias Mericskay, Cecile Bouton, Anne Garnier
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 15:205
Autor:
Romain Tortuyaux, Marc Oudart, Noémie Mazaré, Philippe Mailly, Jean-Christophe Deschemin, Sophie Vaulont, Carole Escartin, Martine Cohen-Salmon
Astrocytes are thought to play a crucial role in brain iron homeostasis. How they accomplish this regulation in vivo remains unclear. In a recent transcriptomic analysis, we showed that polysomal Ftl1 and Fth1 mRNAs, encoding the ferritin light (Ftl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f6b6b685d26fc2323070f6f2b257ded
https://doi.org/10.1101/2022.04.01.486678
https://doi.org/10.1101/2022.04.01.486678
Autor:
Jithu Varghese James, Nikhitha Mariya John, Molly Jacob, Andrew T. McKie, Sophie Vaulont, Jean-Christophe Deschemin, Joe Varghese
Publikováno v:
The Journal of nutritional biochemistry. 111
Increased body iron stores and inflammation in adipose tissue have been implicated in the pathogenesis of insulin resistance (IR) and type 2 diabetes mellitus. However, the underlying basis of these associations are unclear. In order to assess this,