A functional role identified for conserved charged residues at the active site entrance of lipoxygenase with double specificity

Autor: Magali Mariani, Virginie Brunini-Bronzini de Caraffa, Ernst H. Oliw, Jean-Christophe Alberti, Jacques Maury, Liliane Berti, Claude Gambotti

Publikováno v: Journal of Molecular Catalysis B: Enzymatic. 123:167-173

Plant lipoxygenases (LOXs) are a class of widespread dioxygenases catalyzing the hydroperoxidation of free polyunsaturated fatty acids, producing 9-hydroperoxides or 13-hydroperoxides from linoleic and α-linolenic acids, and are called 9-LOX or 13-L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4c5e4cb11640a94721a65de6119ed3a
https://doi.org/10.1016/j.molcatb.2015.10.011

Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies

Autor: Cynthia Palmieri-Thiers, Stéphane Canaan, Virginie Brunini, Félix Tomi, Liliane Berti, Jean-Christophe Alberti, Claude Gambotti, Jacques Maury, Ernst H. Oliw

Publikováno v: Archives of Biochemistry and Biophysics
Archives of Biochemistry and Biophysics, 2011, 509 (1), pp.82-9. ⟨10.1016/j.abb.2011.02.008⟩
Archives of Biochemistry and Biophysics, Elsevier, 2011, 509 (1), pp.82-9. ⟨10.1016/j.abb.2011.02.008⟩

International audience; Lipoxygenases (LOXs) are a class of widespread dioxygenases catalyzing the hydroperoxidation of polyunsaturated fatty acids (PUFA). Recently, we isolated a cDNA encoding a LOX, named olive LOX1, from olive fruit of which the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4914afb0dac613c8fa320386b1361d31
https://pubmed.ncbi.nlm.nih.gov/21345329