Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Jean-Charles Quirion"'
Publikováno v:
Química Nova, Vol 22, Iss 6, Pp 828-837 (1999)
Conformational constraint is an approach which can be used to restrict the flexibility of peptide molecules and to provide information on the topographical requirements of receptors. The incorporation of conformationally constrained units in a peptid
Externí odkaz:
https://doaj.org/article/0cc7df8c1a5245218596ef8b5a70a20d
Autor:
José Angelo Silveira Zuanazzi, Pierre Henri Clergeot, Jean-Charles Quirion, Henri-Philippe Husson, Adam Kondorosi, Pascal Ratet
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 11, Iss 8, Pp 784-794 (1998)
During symbiosis between leguminous plants and rhizobia, flavonoids exuded by the plants act as chemoattractants and nodulation (nod) gene regulators in the other partner. To better understand the role of these compounds during the early steps of the
Externí odkaz:
https://doaj.org/article/d7c4fd4b2c804e05a212922337e2f106
Autor:
Philippe Jubault, Jean-Charles Quirion, Gérald Lemonnier, Cédric Lion, Cyril Goudet, Jean-Philippe Pin
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2012, 20 (15), pp.4716-26. ⟨10.1016/j.bmc.2012.06.006⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2012, 20 (15), pp.4716-26. ⟨10.1016/j.bmc.2012.06.006⟩
International audience; Herein we describe the diastereoselective synthesis of glutamic acid analogs and the evaluation of their agonist activity towards metabotropic glutamate receptor subtype 4 (mGluR4). These analogs are based on a monofluorinated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5869717a25468133c8d7e4b3f83d93
https://doi.org/10.1016/j.bmc.2012.06.006
https://doi.org/10.1016/j.bmc.2012.06.006
Publikováno v:
Journal of Fluorine Chemistry
Journal of Fluorine Chemistry, Elsevier, 2012, 134, pp.172-179. ⟨10.1016/j.jfluchem.2011.02.015⟩
Journal of Fluorine Chemistry, Elsevier, 2012, 134, pp.172-179. ⟨10.1016/j.jfluchem.2011.02.015⟩
International audience; The synthesis of polyhydroxylated 1,1-difluoro-5-methylenecyclopentanes is described. The sequence involves an addition of PhSeCF2TMS to a tartrate-derived aldehyde or its corresponding tert-butanesulfinylimines followed by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903f36e836a97e0abe57dbbcf95ff504
https://doi.org/10.1016/j.jfluchem.2011.02.015
https://doi.org/10.1016/j.jfluchem.2011.02.015
Publikováno v:
The Journal of Organic Chemistry. 74:4124-4131
A efficient methodology allowing the one-pot stereoselective synthesis of alpha-fluoroacrylates, based on the addition of ethyl dibromofluoroacetate to a carbonyl derivative using diethylzinc as organometallic mediator, is described. Two different pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b876e8c9d3f14a7efd657dca0572c6
https://doi.org/10.1021/jo900422m
https://doi.org/10.1021/jo900422m
Publikováno v:
The Journal of Peptide Research. 51:116-120
One unsubstituted and one stereoselectively prepared 3-(S)-substituted-2-oxopiperazine have been used as dipeptide templates to generate tetrapeptide analogues. NMR analysis shows that these tetrapeptide analogues present an inverse gamma-turn confor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971bbb4d08edf874374fc5c5374f6f41
https://doi.org/10.1111/j.1399-3011.1998.tb00628.x
https://doi.org/10.1111/j.1399-3011.1998.tb00628.x
Autor:
Jean-Charles Quirion, Philippe Gloanec, Guillaume De Nanteuil, Nicolas Boyer, Philippe Jubault
Publikováno v:
European Journal of Organic Chemistry. 2008:4277-4295
The synthesis of gem-difluorinated β-lactams and gem-difluorinated β-amino acids, each possessing a potential basic functional group, from ethyl bromodifluoroacetate and either imines (for β-lactams) or N-(α-aminoalkyl)benzotriazoles (for β-amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d24f12fe787cf71b14fe54bbbb2f82
https://doi.org/10.1002/ejoc.200800363
https://doi.org/10.1002/ejoc.200800363
Autor:
Nicolas Boyer, Guillaume De Nanteuil, Philippe Jubault, Jean-Charles Quirion, Philippe Gloanec
Publikováno v:
Tetrahedron. 63:12352-12366
The chemoselective and stereoselective synthesis of gem -difluoro-β-aminoesters or gem -difluoro-β-lactams was investigated from ethylbromodifluoroacetate and imines during Reformatsky reaction. Influence of various reaction parameters, such as nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::032219af8c4547df9ca854f2ad1a7c2f
https://doi.org/10.1016/j.tet.2007.09.058
https://doi.org/10.1016/j.tet.2007.09.058
Publikováno v:
Organic Letters. 9:2477-2480
The synthesis of synthetically useful alpha-CF2-glycosides by radical addition of ethyl bromodifluoroacetate onto 2-benzyloxyglycals is described. The methodology provides an access to alpha-O-glycoside mimics and, potentially, to valuable alpha-O-gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2515e35c26630b7d4d85ae2c9dbc98
https://doi.org/10.1021/ol070835f
https://doi.org/10.1021/ol070835f
Autor:
Navnath P. Karche, Xavier Pannecoucke, Jean-Charles Quirion, Camille Pierry, Hassan Oulyadi, Eric Leclerc, Florent Poulain
Publikováno v:
Synlett. 2007:0123-0126
The first synthesis of β-CF 2 -D-manno- and β-CF 2 -D-galactopyranosylesters la and 1b is reported. It involves an oxidation-Reformatsky addition sequence on carbohydrate-derived diols and a dehydroxylation of the resulting cyclized compounds. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4a22c1d2697be397ef48469d80131c6
https://doi.org/10.1055/s-2006-958414
https://doi.org/10.1055/s-2006-958414