Zobrazeno 1 - 10 of 211 pro vyhledávání: '"Jean-Charles Cerottini"'
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Akademický článek
Tumor cell recognition efficiency by T cells.
Autor: Daniel E Speiser, Jean-Charles Cerottini, Pedro Romero
Publikováno v: PLoS Medicine, Vol 2, Iss 3, p e77; author reply e95 (2005)
Externí odkaz: https://doaj.org/article/d1f89e01b37a464abf0cfb11fc9ca86d
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2
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals
Autor: P R Dunbar, Vincenzo Cerundolo, Daniel E. Speiser, Pedro Romero, Jean-Charles Cerottini, Katharina Fleischhauer, Ferdy Lejeune, Danila Valmori, Danielle Liénard, Mikael J. Pittet
Publikováno v: Journal of Experimental Medicine, vol. 190, no. 5, pp. 705-15
The Journal of Experimental Medicine
Using fluorescent HLA-A*0201 tetramers containing the immunodominant Melan-A/MART-1 (Melan-A) tumor-associated antigen (Ag), we previously observed that metastatic lymph nodes of melanoma patients contain high numbers of Ag-experienced Melan-A-specif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34eb4ae630c7bc379ec6c696b8b211f
https://doi.org/10.1084/jem.190.5.705
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3
Heterogeneity of inhibition of cytolytic T lymphocyte clones by monoclonal anti-Lyt-2/3 antibodies: parallel effects on cytolysis, proliferation and lymphokine secretion
Autor: H R MacDonald, Jean-Charles Cerottini, Andrew L. Glasebrook, Anne Kelso, Claude Bron, O. Acuto
Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781468489613
Scopus-Elsevier
The interaction between cytolytic T lymphocytes (CTL) and target cells is presumed to be mediated by antigen-specific receptors on the surface of CTL. One approach to the identification and characterization of such putative receptors is thus to make
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e2fac191cde386bd251d19b77b24f5
https://ora.ox.ac.uk/objects/uuid:6451959d-6b58-4e7b-bd3a-5bdd3ea61ec7
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4
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes
Autor: Danila Valmori, Pedro Romero, P. Rod Dunbar, Vincenzo Cerundolo, Graham S. Ogg, Jean-Charles Cerottini, Ji-Li Chen, Donata Rimoldi, Mikael J. Pittet, Danielle Liénard
Publikováno v: The Journal of Experimental Medicine
Characterization of cytolytic T lymphocyte (CTL) responses to tumor antigens has been impeded by a lack of direct assays of CTL activity. We have synthesized reagents (“tetramers”) that specifically stain CTLs recognizing melanoma antigens. Tetra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bf893a3d60f9234c4a9bb143619f01
https://ora.ox.ac.uk/objects/uuid:6e063bda-0c58-4e89-abc1-97c4570ca193
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5
Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients
Autor: Hanifa Bouzourene, Gabriel Bricard, Jean Claude R Givel, Pedro M. S. Alves, Theres Fagerberg, Frédéric Lévy, Olivier Michielin, Henri Vuilleumier, Daniel E. Speiser, Sebastien Viatte, Pedro Romero, Thorsten Kruger, Jean Charles Cerottini
Publikováno v: Cancer immunology, immunotherapy, vol. 56, no. 11, pp. 1795-1805
Carcinoembryonic antigen (CEACAM5) is commonly overexpressed in human colon cancer. Several antigenic peptides recognized by cytolytic CD8+ T-cells have been identified and used in colon cancer phase-I vaccination clinical trials. The HLA-A*0201-bind
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca2bca08684f86ca0949ef4b4e3a580
https://doi.org/10.1007/s00262-007-0323-2
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6
Human Effector CD8+ T Lymphocytes Express TLR3 as a Functional Coreceptor
Autor: Julie Tabiasco, Daniel E. Speiser, Estelle Devevre, Jean-Charles Cerottini, Pedro Romero, Nathalie Rufer, Bruno Salaun
Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2006, 177 (12), pp.8708-8713. ⟨10.4049/jimmunol.177.12.8708⟩
Journal of Immunology, 2006, 177 (12), pp.8708-8713. ⟨10.4049/jimmunol.177.12.8708⟩
TLR are evolutionarily conserved molecules that play a key role in the initiation of innate antimicrobial immune responses. Through their influence on dendritic cell maturation, these receptors are also thought to indirectly shape the adaptive immune
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07fa06b9bd61ae25a3168a41ee71321
https://doi.org/10.4049/jimmunol.177.12.8708
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7
New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site
Autor: Severine Reynard, Pedro Romero, Danielle Liénard, Donata Rimoldi, Nathalie Rufer, Serge Leyvraz, Camilla Jandus, Jean Charles Cerottini, Philippe Guillaume, Sarah E. Coupland, Daniel E. Speiser, Victor Appay, Verena Voelter, Arthur M. Krieg
Publikováno v: The Journal of Immunology. 177:1670-1678
Although increasing evidence suggests that CTL are important to fight the development of some cancers, the frequency of detectable tumor-specific T cells is low in cancer patients, and these cells have generally poor functional capacities, compared w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5677ff5407f708f2fcb8bdcdc972c8
https://doi.org/10.4049/jimmunol.177.3.1670
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8
Decreased specific CD8+ T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide
Autor: Catherine Barbey, Clemencia Pinilla, Victor Appay, Severine Reynard, Serge Leyvraz, Pedro Romero, Nathalie Rufer, Jean-Charles Cerottini, Daniel E. Speiser
Publikováno v: European Journal of Immunology. 36:1805-1814
The aim of T cell vaccines is the expansion of antigen-specific T cells able to confer immune protection against pathogens or tumors. Although increase in absolute cell numbers, effector functions and TCR repertoire of vaccine-induced T cells are oft
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c681644f17089a694b94b73cf956fb
https://doi.org/10.1002/eji.200535805
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9
Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex
Autor: Pedro Romero, Jean-Charles Cerottini, Frederic-Anne Le Gal, Pierre-Yves Dietrich, Asma Gati, Gilles Bioley, Alfred Zippelius, Daniel E. Speiser, Mikael J. Pittet, Magda De Smedt, Philippe Guillaume, Jean Plum
Publikováno v: The Journal of Immunology. 176:2330-2336
Alloreactive T cells are thought to be a potentially rich source of high-avidity T cells with therapeutic potential since tolerance to self-Ags is restricted to self-MHC recognition. Given the particularly high frequency of alloreactive T cells in th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b370a4181f1789f03454e74d49cfc84
https://doi.org/10.4049/jimmunol.176.4.2330
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10
Structural Prediction of Peptides Bound to MHC Class I
Autor: Jean-Charles Cerottini, Theres Fagerberg, Olivier Michielin
Publikováno v: Journal of Molecular Biology. 356:521-546
An ab initio structure prediction approach adapted to the peptide-major histocompatibility complex (MHC) class I system is presented. Based on structure comparisons of a large set of peptide-MHC class I complexes, a molecular dynamics protocol is pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e43c56684c59b4cff8735d638618874
https://doi.org/10.1016/j.jmb.2005.11.059
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