Zobrazeno 1 - 10
of 53 906
pro vyhledávání: '"Jean-Charles"'
Autor:
Arnaud Bayle, Laila Belcaid, Sophie Cousin, Kilian Trin, Melissa Alame, Etienne Rouleau, Isabelle Soubeyran, Ludovic Lacroix, Laura Blouin, Damien Vasseur, Amandine Crombe, Simone Mathoulin-Pelissier, Jean-Charles Soria, Carine Bellera, Antoine Italiano
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-5 (2024)
Abstract Selecting patients for phase I cancer trials is crucial to ensure a sufficient life expectancy. Frail patients, better suited for palliative care, should not be exposed to new drugs with minimal benefit. Enrolling patients at high risk of ea
Externí odkaz:
https://doaj.org/article/d05aae3b04e145588413b39998d26d59
Autor:
Damien Vasseur, Ludovic Bigot, Kristi Beshiri, Juan Flórez-Arango, Francesco Facchinetti, Antoine Hollebecque, Lambros Tselikas, Mihaela Aldea, Felix Blanc-Durand, Anas Gazzah, David Planchard, Ludovic Lacroix, Noémie Pata-Merci, Catline Nobre, Alice Da Silva, Claudio Nicotra, Maud Ngo-Camus, Floriane Braye, Sergey I. Nikolaev, Stefan Michiels, Gérôme Jules-Clement, Ken André Olaussen, Fabrice André, Jean-Yves Scoazec, Fabrice Barlesi, Santiago Ponce, Jean-Charles Soria, Benjamin Besse, Yohann Loriot, Luc Friboulet
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Understanding the resistance mechanisms of tumor is crucial for advancing cancer therapies. The prospective MATCH-R trial (NCT02517892), led by Gustave Roussy, aimed to characterize resistance mechanisms to cancer treatments throu
Externí odkaz:
https://doaj.org/article/e6a5668f34d34175ab097af1e5bb22e4
Autor:
Chunyang Dong, Yinghao Wang, Ziqi Deng, Wenchao Wang, Maya Marinova, Karima Ben Tayeb, Jean-Charles Morin, Melanie Dubois, Martine Trentesaux, Yury G. Kolyagin, My Nghe Tran, Vlad Martin-Diaconescu, Olga Safonova, Jeremie Zaffran, Andrei Y. Khodakov, Vitaly V. Ordomsky
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Aliphatic diols such as ethylene and propylene glycol are the key products in the chemical industry for manufacturing polymers. The synthesis of these molecules usually implies sequential processes, including epoxidation of olefins using hyd
Externí odkaz:
https://doaj.org/article/4ddb8a9cc5d04b98a1a287ca6cff1aea
Autor:
Raquel Urena, Sabine Camiade, Yasser Baalla, Martine Piarroux, Laurent Vouriot, Philippe Halfon, Jean Gaudart, Jean-Charles Dufour, Stanislas Rebaudet
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Antibiotic resistance in bacterial pathogens is a major threat to global health, exacerbated by the misuse of antibiotics. In hospital practice, results of bacterial cultures and antibiograms can take several days. Meanwhile, prescribing an
Externí odkaz:
https://doaj.org/article/33eb42abbc884ebf9f751f61d10ce30f
Publikováno v:
Asian Journal of Sport and Exercise Psychology, Vol 4, Iss 2, Pp 38-45 (2024)
The placebo effect is a fascinating phenomenon that has advanced beyond the medical field into the field of sport and exercise psychology. The goal of the present study was to expand this literature by investigating the effects of expectation manipul
Externí odkaz:
https://doaj.org/article/67a33b76224846c2b7a957058c0cfed7
Autor:
Fabio Hecht, Laura Valerio, Carlos Frederico Lima Gonçalves, Marylin Harinquet, Rabii Ameziane El Hassani, Denise P Carvalho, Stephane Koundrioukoff, Jean-Charles Cadoret, Corinne Dupuy
Publikováno v:
European Thyroid Journal, Vol 13, Iss 4, Pp 1-9 (2024)
Objective: Ionizing radiation generates genomic instability by promoting the accumulation of chromosomal rearrangements. The oncogenic translocation RET/PTC1 is present in more than 70% of radiation-induced thyroid cancers. Both RET and CCDC6, the ge
Externí odkaz:
https://doaj.org/article/3f7d45cd41f1485cb517d7dde280a482
Autor:
Audrey Frances, Audrey Lumeau, Nicolas Bery, Marion Gayral, Lucille Stuani, Marie Sorbara, Estelle Saland, Delphine Pagan, Naïma Hanoun, Jérôme Torrisani, Anthony Lemarié, Jean-Charles Portais, Louis Buscail, Nelson Dusetti, Jean-Emmanuel Sarry, Pierre Cordelier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Cytidine deaminase (CDA) converts cytidine and deoxycytidine into uridine and deoxyuridine as part of the pyrimidine salvage pathway. Elevated levels of CDA are found in pancreatic tumors and associated with chemoresistance. Recent evidence
Externí odkaz:
https://doaj.org/article/24345386e0cc41aab556d3b00292c6da
Autor:
Artida Ulaj, Arni Ibsen, Leire Azurmendi, Jean-Charles Sanchez, Virginie Prendki, Xavier Roux
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Purpose Elderly patients with suspected pneumonia represent a significant proportion of hospital admissions, which is a prognostic challenge for physicians. Our research aimed to assess the prognosis of patients with pneumonia using soluble
Externí odkaz:
https://doaj.org/article/1556b4fa8bfd4cfc922cdbe463b873e3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Late-life depression (LLD) is both common and disabling and doubles the risk of dementia onset. Apathy might constitute an additional risk of cognitive decline but clear understanding of its pathophysiology is lacking. While white matter (WM
Externí odkaz:
https://doaj.org/article/9dcc4728fc6642a19065afc9a72dfd6b
Autor:
Behnam Ahmadikia, Dalton Shadle, Jean-Charles Stinville, Kelly E. Nygren, M. Arul Kumar, Tresa M. Pollock, Matthew P. Miller, Irene J. Beyerlein
Publikováno v:
Journal of Materials Research and Technology, Vol 33, Iss , Pp 168-179 (2024)
In this work, we study the relationship between slip localizations and local orientation gradients in a polycrystalline material. We employ a 3D spatially resolved crystal plasticity-based micromechanics technique that includes explicit intragranular
Externí odkaz:
https://doaj.org/article/35069ee652b2471cb852f40614a03bd3