Výsledky vyhledávání - "Jean-Bernard Bongui"

Phytochemical Screening and Evaluation of the Anti-Radical and Antimicrobial Activities of Extracts of Artemisia annua L. and Artemisia afra Jacq. Cultivated in Gabon

Autor: Ghismel NZAMBA MOUSSAVOU, NKOLO, Paulin, Joefred MBOGHO ABOGO, N'NANG, Elvis OTOGO, OBIANG, Cédric SIMA, LEBIBI, Jacques, Jean-Bernard BONGUI

Artemisia afra and Artemisia annua are two medicinal plants used in the treatment of several diseases including malaria in South Africa and China respectively. In Gabon, these plant species are cultivated by the Maison de l'Artemisia, which promotes

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A new dibenzofuran derivative from the stem bark of Scyphocephalium ochocoa with anti-inflammatory and cytotoxic activities

Autor: Jean Claude Tchouankeu, Hibrahim Foundikou, Jacques Lebibi, Guy Raymond Feuya Tchouya, Jean Jules Bankeu Kezetas, Jean-Bernard Bongui, Marius Mbiantcha, Dattatraya H. Dethe

Publikováno v: Natural Product Research. 36:1503-1514

The phytochemical investigation of the dichloromethane/methanol (1:1) extract of the stem bark of Scyphocephalium ochocoa, led to the isolation of one new dibenzofuran derivative, named scyphocephalione A (1), along with three other compounds, includ

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https://doi.org/10.1080/14786419.2021.1894561

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Structure−Activity Relationships and Mechanism of Action of Antitumor Benzo[b]pyrano[3,2-h]acridin-7-one Acronycine Analogues

Autor: Bruno Pfeiffer, Marie-Hélène David-Cordonnier, Francois Tillequin, S. Leonce, Michel Koch, William Laine, Sylvie Michel, Huong Doan Thi Mai, Thomas Gaslonde, John Hickman, Laurence Kraus-Berthier, Elisabeth Seguin, Jean-Bernard Bongui, Christian Bailly, Pierre Renard, Alain Pierre, Abdelhakim Elomri

Publikováno v: Journal of Medicinal Chemistry. 46:3072-3082

The cytotoxic and antitumor activities of cis-1,2-diacyloxy-6-methoxy-3,3,14-trimethyl-1,2,3,14-tetrahydro-7H-benzo[b]pyrano[3,2-h]acridin-7-one derivatives 3, 6-9 were strongly correlated with their ability to give covalent adducts with purified, as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272ea39fb8b9f6a7dbb75c5a454ac03b
https://doi.org/10.1021/jm030790y

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Synthesis and Cytotoxic Activity of Benzophenanthrolinone Analogues of Acronycine

Autor: Bruno Pfeiffer, Pierre Renard, Jean-Bernard Bongui, Francois Tillequin, Ghanem Atassi, Abdelhakim Elomri, Elisabeth Seguin, Alain Pierre

Publikováno v: Chemical and Pharmaceutical Bulletin. 49:1077-1080

Condensation of either 2-bromobenzoic acid (4) or 2-chloro-3-nitrobenzoic acid (5) with suitable aminoquinolines 6-8 afforded phenylquinolylamines 9-13. Acid mediated cyclization gave the corresponding 12H-benzo[b][1,7]phenanthrolin-7-ones 14 and 15,

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https://doi.org/10.1248/cpb.49.1077

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In vitro antiplasmodial activity and cytotoxicity of extracts and fractions of Vitex madiensis, medicinal plant of Gabon

Autor: Joseph Privat Ondo, Jean-Bernard Bongui, Jacques Lebibi, E. S. Zang Edou, Fousseyni S. Toure-Ndouo, Jean-Bernard Lekana-Douki, Rafika Zatra, Elisabeth Seguin, Abdelhakim Elomri

Publikováno v: Tropical Medicine & International Health.

Vitex madiensis Oliv. (Lamiaceae) is traditionally used to treat malaria symptoms in Haut-Ogooue, Gabon. Leaves and stem barks extracts were obtained using dichloromethane (CH(2)Cl(2)), ethyl acetate (EtOAc) and methanol (MeOH) as extraction solvents

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https://doi.org/10.1111/j.1365-3156.2011.02922.x

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In vitro antiplasmodial activity of crude extracts of Tetrapleura tetraptera and Copaifera religiosa

Autor: Jean Bernard Lekana-Douki, Jacques Lebibi, Sandrine Lydie Oyegue Liabagui, Fousseyni S. Toure-Ndouo, Rafika Zatra, Jean Bernard Bongui

Publikováno v: BMC Research Notes
BMC Research Notes, Vol 4, Iss 1, p 506 (2011)

Background Malaria remains a major public health problem, especially in tropical and subtropical regions because of the emergence and widespread of antimalarial drug resistance. Traditional medicine represents one potential source of new treatments.

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https://pubmed.ncbi.nlm.nih.gov/22112366

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Preparation of both enantiomers of a synthon for novel nucleoside analogs by enzymatic desymmetrization of a meso-diol with a methylene cyclopropane skeleton

Autor: Nicolas Vanthuyne, Hélène Pellissier, Gérard Audran, Germain Obame, Jean-Bernard Bongui

Publikováno v: Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2011, 52 (10), pp.1082--1085. ⟨10.1016/j.tetlet.2010.12.097⟩
Tetrahedron Letters, 2011, 52 (10), pp.1082--1085. ⟨10.1016/j.tetlet.2010.12.097⟩

International audience; The enzymatic desymmetrization of methylenecyclopropane diol or its corresponding diacetate derivative, generated from a [2+1] cycloaddition between dioxepin and methylchlorocarbene, is described. After screening five commerci

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https://hal.archives-ouvertes.fr/hal-01460336

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