Výsledky vyhledávání - "Jean-Bastien Bott"

Medial septum glutamate neurons are essential for spatial goal-directed memory

Autor: Jean-Bastien Bott, Jennifer Robinson, Frederic Manseau, Etienne Gauthier-Lafrenière, Sylvain Williams

The medial septum (MS), a brain region containing acetylcholine, GABA and glutamate neurons, is essential for learning and memory. However, whether MS glutamate neurons contribute to memory is unknown. Here, we use calcium imaging and optogenetic sil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51f0dfe0cd7336dbde470ad6e9758b50
https://doi.org/10.1101/2022.03.16.484657

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Autor: Chantal Mathis, Karine Herbeaux, Ayikoe Guy Mensah-Nyagan, Aurélia Cès, Céline Héraud, Jean-Bastien Bott, Thibaut Burg

Publikováno v: Neurobiology of Aging
Neurobiology of Aging, Elsevier, 2018, 62, pp.120-129. ⟨10.1016/j.neurobiolaging.2017.10.013⟩

International audience; Aging is associated with impaired performance in behavioral pattern separation (PS) tasks based on similarities in object features and in object location. These deficits have been attributed to functional alterations in the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c54c0e0dd0186392bf540469b2d06a
https://linkinghub.elsevier.com/retrieve/pii/S0197458017303524

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APOE -Sensitive Cholinergic Sprouting Compensates for Hippocampal Dysfunctions Due to Reduced Entorhinal Input

Autor: Karine Herbeaux, Romain Goutagny, Maxime Sartori, Brigitte Cosquer, Jean-Bastien Bott, Chantal Mathis, Céline Héraud, Julien Aubert

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2016, 36 (40), pp.10472-10486. ⟨10.1523/JNEUROSCI.1174-16.2016⟩

Brain mechanisms compensating for cerebral lesions may mitigate the progression of chronic neurodegenerative disorders such as Alzheimer's disease (AD). Mild cognitive impairment (MCI), which often precedes AD, is characterized by neuronal loss in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68366c55b2314fd7d6f750faf83f00d
https://hal.archives-ouvertes.fr/hal-02166087

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Spatial Reference Memory is Associated with Modulation of Theta–Gamma Coupling in the Dentate Gyrus

Autor: Romain Goutagny, Julien Aubert, Chantal Mathis, Jean-Christophe Cassel, Marc-Antoine Muller, Jean-Bastien Bott, Jesse Jackson

Publikováno v: Cerebral Cortex
Cerebral Cortex, Oxford University Press (OUP), 2016, 26 (9), pp.3744-3753. ⟨10.1093/cercor/bhv177⟩

Spatial reference memory in rodents represents a unique opportunity to study brain mechanisms responsible for encoding, storage and retrieval of a memory. Even though its reliance on hippocampal networks has long been established, the precise computa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1848bc192df97a5db5027af355b1fda
https://hal.archives-ouvertes.fr/hal-02166094

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Reversal of theta rhythm flow through intact hippocampal circuits

Autor: Jesse Jackson, Steven L. Bressler, Sylvain Williams, Bénédicte Amilhon, Christian Kortleven, Frédéric Manseau, Jean-Bastien Bott, Romain Goutagny

Publikováno v: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2014, 17 (10), pp.1362-1370. ⟨10.1038/nn.3803⟩

Activity flow through the hippocampus is thought to arise exclusively from unidirectional excitatory synaptic signaling from CA3 to CA1 to the subiculum. Theta rhythms are important for hippocampal synchronization during episodic memory processing; t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4480f1aba575b84893be536ac46dc0dc
https://pubmed.ncbi.nlm.nih.gov/25254978

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Defective response inhibition and collicular noradrenaline enrichment in mice with duplicated retinotopic map in the superior colliculus

Autor: Elise Savier, Vincent Lelievre, Yannick Goumon, Nicholas Bevins, Chantal Mathis, Daniel Clesse, Christian Kelche, Dominique Sage-Ciocca, Anaïs Gillet, Jean-Christophe Cassel, Adrien Lacaud, Jean-Bastien Bott, Frank W. Pfrieger, Alexis Laux-Biehlmann, Karin Geiger, Michael Reber

Publikováno v: Brain Structure and Function
Brain Structure and Function, Springer Verlag, 2014, 220 (3), pp.1573-1584. ⟨10.1007/s00429-014-0745-5⟩
Brain Structure & Function

The superior colliculus is a hub for multisensory integration necessary for visuo-spatial orientation, control of gaze movements and attention. The multiple functions of the superior colliculus have prompted hypotheses about its involvement in neurop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fca2746152f55dfc4d2b8102158cdb
https://hal.archives-ouvertes.fr/hal-02884507

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Reduced plasticity and mild cognitive impairment-like deficits after entorhinal lesions in hAPP/APOE4 mice

Autor: Jean-Bastien Bott, Celina Zerbinatti, Céline Héraud, Christian Kelche, Brigitte Cosquer, Jean-Christophe Cassel, Chantal Mathis

Publikováno v: Neurobiology of aging. 34(11)

Mild cognitive impairment (MCI) is a clinical condition that often precedes Alzheimer disease (AD). Compared with apolipoprotein E-e3 (APOE3), the apolipoprotein E-e4 (APOE4) allele is associated with an increased risk of developing MCI and spatial n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ef46c85585ad010dab7a63a64024f5
https://pubmed.ncbi.nlm.nih.gov/23706647

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ApoE4 confers better spatial memory than apoE3 in young adult hAPP-Yac/apoE-TR mice

Autor: P. Moreau, John J. Renger, Christian Kelche, Jean-Bastien Bott, Celina Zerbinatti, Chantal Mathis, Jean-Christophe Cassel

Publikováno v: Behavioural brain research. 243

The APOE-ɛ4 allele is associated with increased cognitive decline during normal aging and Alzheimer's disease. However, several studies intriguingly found a beneficial effect on cognition in young adult human APOE-ɛ4 carriers. Here, we show that 3-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a7ecfb81c0a523f1d195a502114cb4
https://pubmed.ncbi.nlm.nih.gov/23291160

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Impaired striatum-dependent behavior in GASP-1-knock-out mice

Autor: Marie-Pierre Candusso, Jean-Bastien Bott, Frédéric Simonin, Chantal Mathis, Jean-Christophe Cassel

Publikováno v: Genes, Brain and Behavior
Genes, Brain and Behavior, Wiley, 2010, 10 (3), pp.299-308. ⟨10.1111/j.1601-183X.2010.00666.x⟩

G protein-coupled receptor (GPCR) associated sorting protein-1 (GASP-1) is suspected to play a key role in recycling and degradation of several GPCRs. In a previous study, we have shown that GASP-1-knock-out (GASP-1-KO) mice displayed deficits in acq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591c0e838ff248b2f17c2d05580f6faa
https://pubmed.ncbi.nlm.nih.gov/21091868

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