Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jean-Baptiste Perot"'
Autor:
Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Alzheimer’s disease (AD) is characterized by intracerebral deposition of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These peptides and proteins induce synaptic dysfunctions that are strongly correl
Externí odkaz:
https://doaj.org/article/8307e6636dd947a5bdd092741308d2d4
Autor:
Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain
Background Alzheimer’s disease (AD) is characterized by intracerebral accumulation of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These lesions induce synaptic dysfunctions that are strongly correlated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::180efee41becf67c645905e930eb6eb3
https://doi.org/10.21203/rs.3.rs-2334976/v1
https://doi.org/10.21203/rs.3.rs-2334976/v1
Autor:
Chantal Weber, Nadia Messaddeq, Antoine Hache, Frédéric Doussau, Aurélie Eisenmann, Anna Niewiadomska-Cimicka, Marie-France Champy, Yvon Trottier, Michel Roux, Julien Flament, Erwan Grandgirard, Hamid Meziane, Céline Keime, Binnaz Yalcin, Philippe Isope, Alice Karam, Jean-Baptiste Perot, Hoa Huu Phuc Nguyen, Françoise Piguet, Emmanuel Brouillet, Ariana Novati
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
The journal of neuroscience
J Neurosci
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
Journal of Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
The journal of neuroscience
J Neurosci
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
Spinocerebellar ataxia type 7 (SCA7) is an inherited neurodegenerative disease mainly characterized by motor incoordination because of progressive cerebellar degeneration. SCA7 is caused by polyglutamine expansion in ATXN7, a subunit of the transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea85b30c6dc1216aedad93c59f1bc02e
https://hal.science/hal-03378998
https://hal.science/hal-03378998
Autor:
Emmanuel Brouillet, Julien Flament, Jean-Baptiste Perot, Kalina Wiatr, Maciej Figiel, L. Marczak
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Spinocerebellar ataxia type 3 (SCA3/MJD) is caused by CAG expansion mutation resulting in a long polyQ domain in mutant ataxin-3. The mutant protein is a special type of protease, deubiquitinase, which may indicate its prominent impact on the regulat
Autor:
Emmanuel Brouillet, Hoa Huu Phuc Nguyen, Ariana Novati, Marie-France Champy, Nadia Messaddeq, Yvon Trottier, Alice Karam, Erwan Grandgirard, Jean-Baptiste Perot, Julien Flament, Aurélie Eisenmann, Philippe Isope, Françoise Piguet, Antoine Hache, Hamid Meziane, Frédéric Doussau, Céline Keime, Binnaz Yalcin, Anna Niewiadomska-Cimicka, Chantal Weber, Michel Roux
Background Background: Spinocerebellar ataxia type 7 (SCA7) is primarily characterized by progressive cerebellar degeneration with major alteration of Purkinje cells (PC) due to polyglutamine expansion in ATXN7, a subunit of SAGA transcriptional co-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d258ea71db38a726bfe0618f797ce1
https://doi.org/10.21203/rs.3.rs-27474/v1
https://doi.org/10.21203/rs.3.rs-27474/v1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Huntington’s disease is an inherited disorder characterized by psychiatric, cognitive, and motor symptoms due to degeneration of medium spiny neurons in the striatum. A prodromal phase precedes the onset, lasting decades. Current biomarkers include
Externí odkaz:
https://doaj.org/article/58f45c2b56ae4279a7aab55ce01f7769
Autor:
Jean-Baptiste Pérot, Anna Niewiadomska-Cimicka, Emmanuel Brouillet, Yvon Trottier, Julien Flament
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/06d375aa85d2492a84114e10af070394
Autor:
Elsa C. Kuijper, Maurice Overzier, Ernst Suidgeest, Oleh Dzyubachyk, Cécile Maguin, Jean-Baptiste Pérot, Julien Flament, Yavuz Ariyurek, Hailiang Mei, Ronald A.M. Buijsen, Louise van der Weerd, Willeke van Roon-Mom
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106368- (2024)
In Huntington disease, cellular toxicity is particularly caused by toxic protein fragments generated from the mutant huntingtin (HTT) protein. By modifying the HTT protein, we aim to reduce proteolytic cleavage and ameliorate the consequences of muta
Externí odkaz:
https://doaj.org/article/0b4874be3df4497fb539494749184266
Autor:
Firas Farhat, Jean-Francois Grosset, Megane Beldjelali Labro, Jean-Baptiste Perot, Fahmi Bedoui, Murielle Dufresne, Alejandro Garcia Garcia, Quentin Dermigny, Cécile Legallais
Publikováno v:
SoSE
Biomimetic approaches in tissue engineering consist in collecting knowledge for native tissues or organs to propose novel solutions to reconstruct them in vitro. As an example, the musculo-skeletal continuum can be described using a system of system
Autor:
Kalina Wiatr, Łukasz Marczak, Jean-Baptiste Pérot, Emmanuel Brouillet, Julien Flament, Maciej Figiel
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Spinocerebellar ataxia type 3 (SCA3/MJD) is caused by CAG expansion mutation resulting in a long polyQ domain in mutant ataxin-3. The mutant protein is a special type of protease, deubiquitinase, which may indicate its prominent impact on the regulat
Externí odkaz:
https://doaj.org/article/7a4c91f909c24f0e9962e82f252ab731