Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jean Y.-Q. Hu"'
Autor:
Xiaoping Chen, Mohamed El Gazzar, Charles E. McCall, Barbara K. Yoza, Jean Y.-Q. Hu, Sue L. Cousart
Publikováno v:
Clinical and Vaccine Immunology. 16:104-110
Transcription factors and chromatin structural modifiers induce clinically relevant epigenetic modifications of blood leukocytes during severe systemic inflammation (SSI) in humans and animals. These changes affect genes with distinct functions, as e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c1295896be6385cfb55e2189241c575
https://doi.org/10.1128/cvi.00320-08
https://doi.org/10.1128/cvi.00320-08
Publikováno v:
The Journal of Immunology. 177:4080-4085
Using a THP-1 human promonocyte model of endotoxin tolerance that simulates the sepsis leukocyte phenotype, we previously showed that tolerant cells remain responsive to LPS endotoxin with degradation of IκB in the cytosol and nuclear translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73637748e12d09a82c17f594f838ef29
https://doi.org/10.4049/jimmunol.177.6.4080
https://doi.org/10.4049/jimmunol.177.6.4080
Publikováno v:
Journal of Endotoxin Research. 8:109-114
Covalent modification of histones and the subsequent remodeling of chromatin have emerged as important mechanisms in regulating gene expression. In particular, recent identification of the enzyme families responsible for the steady-state balance of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4596fb4b0acdc37ee600e94189a2d19
https://doi.org/10.1177/09680519020080020401
https://doi.org/10.1177/09680519020080020401
Publikováno v:
Journal of Biological Chemistry. 271:18306-18309
In human monocytes, interleukin 1beta protein production and steady state mRNA levels are increased in response to lipopolysaccharide, predominantly as a result of increased transcription of the interleukin 1beta gene. Expression of interleukin 1beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01869acdd9509b08da6623549b387fca
https://doi.org/10.1074/jbc.271.31.18306
https://doi.org/10.1074/jbc.271.31.18306
Autor:
Xiaoping, Chen, Barbara K, Yoza, Mohamed, El Gazzar, Jean Y Q, Hu, Sue L, Cousart, Charles E, McCall
Publikováno v:
Clinical and vaccine immunology : CVI. 16(1)
Transcription factors and chromatin structural modifiers induce clinically relevant epigenetic modifications of blood leukocytes during severe systemic inflammation (SSI) in humans and animals. These changes affect genes with distinct functions, as e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a767e8ab9b3dc9afe6beb86d33a7a6f3
https://pubmed.ncbi.nlm.nih.gov/19020113
https://pubmed.ncbi.nlm.nih.gov/19020113
Publikováno v:
Shock (Augusta, Ga.). 13(3)
Stimulation of the human promonocytic cell line, THP-1, with endotoxin results in a rapid and transient increase in interleukin 1beta expression. Endotoxin pretreatment of THP-1 cells results in tolerance, characterized by decreased levels of endotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cc440789a285c5583b45d436f5a7c5
https://pubmed.ncbi.nlm.nih.gov/10718382
https://pubmed.ncbi.nlm.nih.gov/10718382