Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean Y. Wang"'
Autor:
Xuesong Liu, Yan Shi, Keith W. Woods, Paul Hessler, Paul Kroeger, Julie Wilsbacher, Jieyi Wang, Jean Y. Wang, Chunying Li, Qun Li, Saul H. Rosenberg, Vincent L. Giranda, Yan Luo
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 8, Pp 828-837 (2008)
Both Akt and Aurora A kinase have been shown to be important targets for intervention for cancer therapy. We report here that Compound A (A-443654), a specific Akt inhibitor, interferes with mitotic progression and bipolar spindle formation. Compound
Externí odkaz:
https://doaj.org/article/f6c80b51bea0494ca302ce26868e7245
Autor:
Mitchell P Levesque, Teva Vernoux, Wolfgang Busch, Hongchang Cui, Jean Y Wang, Ikram Blilou, Hala Hassan, Keiji Nakajima, Noritaka Matsumoto, Jan U Lohmann, Ben Scheres, Philip N Benfey
Publikováno v:
PLoS Biology, Vol 4, Iss 7 (2006)
Meta-analysis to combine the results of several microarray experiments reveals a new function for the transcription factor SHORT-ROOT in the development of vascular tissue.
Externí odkaz:
https://doaj.org/article/fe89a78803ba41838ae34fc911637932
Publikováno v:
Cancer Research. 79:2573-2573
DNA damaging agents (DDAs) based chemotherapies are the first and still the most widely used anticancer treatments. However, quickly developed drug resistance of cancer cells often impedes their efficacies. Two independent transcriptome analyses in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84095d2ac5851cff78a98c7ed3f2c2ea
https://doi.org/10.1158/1538-7445.am2019-2573
https://doi.org/10.1158/1538-7445.am2019-2573
Publikováno v:
Nucleic Acids Research
Understanding the differences between microarray and RNA-Seq technologies for measuring gene expression is necessary for informed design of experiments and choice of data analysis methods. Previous comparisons have come to sometimes contradictory con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c220a76df91563ff3e85797961dac7a
Publikováno v:
Journal of Orthopaedic Research. 20:83-91
Periods of reduced joint loading have been shown to induce changes in the biochemical composition, metabolism and mechanics of articular cartilage. In this study, changes in cartilage swelling behavior were studied following a 4-week period of joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a831e2417a44b2ec61fa05dad51e7e
https://doi.org/10.1016/s0736-0266(01)00076-6
https://doi.org/10.1016/s0736-0266(01)00076-6
Publikováno v:
Biophysical Journal. 81:3066-3076
Articular cartilage is one of several biological tissues in which swelling effects are important in tissue mechanics and function, and may serve as an indicator of degenerative joint disease. This work presents a new approach to quantify swelling eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fffdabea5582431959e3b703e320f72
https://doi.org/10.1016/s0006-3495(01)75945-0
https://doi.org/10.1016/s0006-3495(01)75945-0
Publikováno v:
Spine. 26:1747-1751
Study Design. The mRNA levels of aggrecan and collagen were quantified in intervertebral disc cells cultured under three conditions: primary alginate culture, monolayer culture, and re-encapsulation in alginate after monolayer culture. Objectives. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211974a183a45a34aeefdcc702c51037
https://doi.org/10.1097/00007632-200108150-00003
https://doi.org/10.1097/00007632-200108150-00003
Publikováno v:
Journal of Orthopaedic Research. 19:2-10
Cells of the intervertebral disc have a limited capacity for matrix repair that may contribute to the onset and progression of degenerative disc changes. In this study, the biosynthetic capacity of cells isolated from specific regions of the porcine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bb54d0a666b5a64c63631853bdc01b
https://doi.org/10.1016/s0736-0266(00)00003-6
https://doi.org/10.1016/s0736-0266(00)00003-6
Publikováno v:
Journal of Biomechanics. 32:401-408
Swelling effects in cartilage originate from an interstitial osmotic pressure generated by the presence of negatively charged proteoglycans in the tissue. This swelling pressure gives rise to a non-zero residual strain in the cartilage solid matrix i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ac81f1831034a69441fc79954ad41a
https://doi.org/10.1016/s0021-9290(98)00184-5
https://doi.org/10.1016/s0021-9290(98)00184-5
Autor:
Ewa Malatynska, Nathan Collins, Richard J. Knapp, Jean Y. Wang, Victor J. Hruby, Lei Fang, Henry I. Yamamura, William R. Roeske
Publikováno v:
The FASEB Journal. 9:516-525
The cloning and expression of DNA for the three major opioid receptor types (mu, delta, and kappa) present new research opportunities for the characterization of opioid drugs and their interactions with these receptors. Genomic and cDNA clones for op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9519a33d23dcba965062b1bfb6215e
https://doi.org/10.1096/fasebj.9.7.7737460
https://doi.org/10.1096/fasebj.9.7.7737460