Výsledky vyhledávání - "Jean Y. Chen"

An 11-Amino Acid Sequence from c-met Initiates Epithelial Chemotaxis via Phosphatidylinositol 3-Kinase and Phospholipase C

Autor: Katherine Spokes, Jean Y. Chen, Melanie P. Derman, Lloyd G. Cantley, Zhou Songyang

Publikováno v: Journal of Biological Chemistry. 271:4251-4255

Interaction of hepatocyte growth factor with its high affinity receptor c-met initiates a cascade of intracellular events leading to epithelial motility. An 11-amino acid sequence from the c-met receptor has been found to cause cell transformation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b622485788eaf96cb7f007553cfd0a
https://doi.org/10.1074/jbc.271.8.4251

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Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet

Autor: Jean Y. Chen, Allen D. Cooper, Sheryl A. Goodart, Beatriz Levy-Wilson

Publikováno v: The Journal of biological chemistry. 277(45)

Cholesterol 7alpha-hydroxylase (CYP7A1) catalyzes the rate-limiting step in the pathway responsible for the formation of the majority of bile acids. Transcription of the gene is regulated by the size of the bile acid pool and dietary and hormonal fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4252da4091b041a48e339c3e617d2cc1
https://pubmed.ncbi.nlm.nih.gov/12202481

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