Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jean Y Gouzi"'
Autor:
James A Walker, Jean Y Gouzi, Jennifer B Long, Sidong Huang, Robert C Maher, Hongjing Xia, Kheyal Khalil, Arjun Ray, David Van Vactor, René Bernards, André Bernards
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003958 (2013)
Neurofibromatosis type 1 (NF1), a genetic disease that affects 1 in 3,000, is caused by loss of a large evolutionary conserved protein that serves as a GTPase Activating Protein (GAP) for Ras. Among Drosophila melanogaster Nf1 (dNf1) null mutant phen
Externí odkaz:
https://doaj.org/article/6a6fbe63095a43cf9e557c776fefd3de
The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning.
Autor:
Jean Y Gouzi, Anastasios Moressis, James A Walker, Anthi A Apostolopoulou, Ruth H Palmer, André Bernards, Efthimios M C Skoulakis
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002281 (2011)
Anaplastic Lymphoma Kinase (Alk) is a Receptor Tyrosine Kinase (RTK) activated in several cancers, but with largely unknown physiological functions. We report two unexpected roles for the Drosophila ortholog dAlk, in body size determination and assoc
Externí odkaz:
https://doaj.org/article/62e53bc031b248e2b73e399c11b560eb
Autor:
Ilianna G. Roussou, Katerina Papanikolopoulou, Martina Samiotaki, Efthimios M. C. Skoulakis, Jean Y. Gouzi, Luca Turin, George Panayotou
Publikováno v:
The Journal of Neuroscience. 39:8315-8329
Although the involvement of pathological tau in neurodegenerative dementias is indisputable, its physiological roles have remained elusive in part because its abrogation has been reported without overt phenotypes in mice andDrosophila. This was addre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a38aa76560365124a0d4190ef352d6
https://doi.org/10.1523/jneurosci.0391-19.2019
https://doi.org/10.1523/jneurosci.0391-19.2019
Autor:
Ilianna G. Roussou, Jean Y. Gouzi, Anastasios Moressis, Mikela Bouraimi, Efthimios M. C. Skoulakis
Publikováno v:
The Journal of Neuroscience. 38:7701-7712
In addition to mechanisms promoting protein-synthesis dependent long-term memory (PSD-LTM), the process appears to also be specifically constrained. We present evidence that the highly conserved Receptor Tyrosine Kinase dAlk is a novel PSD-LTM attenu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81769175352931e6be1065c39c5b690f
https://doi.org/10.1523/jneurosci.0784-18.2018
https://doi.org/10.1523/jneurosci.0784-18.2018
Autor:
Jean Y, Gouzi, Mikela, Bouraimi, Ilianna G, Roussou, Anastasios, Moressis, Efthimios M C, Skoulakis
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(35)
In addition to mechanisms promoting protein-synthesis-dependent long-term memory (PSD-LTM), the process appears to also be specifically constrained. We present evidence that the highly conserved receptor tyrosine kinase dAlk is a novel PSD-LTM attenu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69ead9c471dc387e9fcbb35ef25c2ab7
https://pubmed.ncbi.nlm.nih.gov/30030398
https://pubmed.ncbi.nlm.nih.gov/30030398
Autor:
Sidong Huang, René Bernards, Jean Y. Gouzi, Robert C. Maher, James A. Walker, Arjun Ray, Kheyal Khalil, Hongjing Xia, David Van Vactor, Jennifer B. Long, Andre Bernards
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 9, Iss 11, p e1003958 (2013)
PLoS Genetics, Vol 9, Iss 11, p e1003958 (2013)
Neurofibromatosis type 1 (NF1), a genetic disease that affects 1 in 3,000, is caused by loss of a large evolutionary conserved protein that serves as a GTPase Activating Protein (GAP) for Ras. Among Drosophila melanogaster Nf1 (dNf1) null mutant phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d5f648a7d3c4400efb261cdb415bd
https://pubmed.ncbi.nlm.nih.gov/24278035
https://pubmed.ncbi.nlm.nih.gov/24278035
Publikováno v:
Neurofibromatosis Type 1 ISBN: 9783642328633
NF1 is a highly variable and unpredictable disease. Symptom-specific genetic modifiers have been implicated as important determinants of disease development and progression. The identification of genes that affect NF1 outcome continues to be an impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b048373cca7611616a2786b03423e33d
https://doi.org/10.1007/978-3-642-32864-0_34
https://doi.org/10.1007/978-3-642-32864-0_34
Publikováno v:
Journal of cell science. 118(Pt 24)
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase essentially and transiently expressed in specific areas of the developing central and peripheral nervous systems. We previously demonstrated that a membrane-bound and constitutively activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb803690e154e8c4a2165e64dce63fa1
https://pubmed.ncbi.nlm.nih.gov/16317043
https://pubmed.ncbi.nlm.nih.gov/16317043
Autor:
Joffrey Degoutin, Jean Y. Gouzi, Jocelyne Bureau, Christophe Créminon, Marc Vigny, Christel Moog-Lutz, Yvelyne B. Frobert, Nicole Brunet-de Carvalho
Publikováno v:
The Journal of biological chemistry. 280(28)
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that is transiently expressed in specific regions of the central and peripheral nervous systems, suggesting a role in its normal development and function. The nature of the cognate ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c678bc54247085834bf46a171638b2b7
https://pubmed.ncbi.nlm.nih.gov/15886198
https://pubmed.ncbi.nlm.nih.gov/15886198
Autor:
James A. Walker, Ruth H. Palmer, Efthimios M. C. Skoulakis, Anastasios Moressis, Anthi A. Apostolopoulou, Jean Y. Gouzi, Andre Bernards
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002281 (2011)
PLoS Genetics
PLoS Genetics
Anaplastic Lymphoma Kinase (Alk) is a Receptor Tyrosine Kinase (RTK) activated in several cancers, but with largely unknown physiological functions. We report two unexpected roles for the Drosophila ortholog dAlk, in body size determination and assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f39a4fd9fae04e875c4da6ae5da668
https://doi.org/10.1371/journal.pgen.1002281
https://doi.org/10.1371/journal.pgen.1002281