Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jean Viallet"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dysregulation of the immune system is associated with many pathologies, including cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in biomedical research are rodents, and despite the various advantages they offer,
Externí odkaz:
https://doaj.org/article/89a608a5e64746bab473da488cd22584
Autor:
Iman W. Achkar, Sara Kader, Shaima S. Dib, Kulsoom Junejo, Salha Bujassoum Al-Bader, Shahina Hayat, Aditya M. Bhagwat, Xavier Rousset, Yan Wang, Jean Viallet, Karsten Suhre, Anna Halama
Publikováno v:
Metabolites, Vol 10, Iss 7, p 268 (2020)
Background: Dysregulated cancer metabolism is associated with acquired resistance to chemotherapeutic treatment and contributes to the activation of cancer survival mechanisms. However, which metabolic pathways are activated following treatment often
Externí odkaz:
https://doaj.org/article/94a9ba78ea834da19032f3af12eb7e26
Autor:
Yusra Al Dhaheri, Samir Attoub, Kholoud Arafat, Synan Abuqamar, Jean Viallet, Alaaeldin Saleh, Hala Al Agha, Ali Eid, Rabah Iratni
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68808 (2013)
BACKGROUND: We have recently reported that Origanummajorana exhibits anticancer activity by promoting cell cycle arrest and apoptosis of the metastatic MDA-MB-231 breast cancer cell line. Here, we extended our study by investigating the effect of O.
Externí odkaz:
https://doaj.org/article/1a8666fe1c8f47c7ba8727eb97b0b70b
Autor:
Guillermo Garcia-Manero, Susan O'Brien, Jean Viallet, Francesco Paolo Tambaro, Yumin Hu, Hui Yang, Yu Jia, Ming Zhang, Weigang Tong, Tapan Kadia, Yue Wei
Supplementary Data from The Combination of a Histone Deacetylase Inhibitor with the Bcl-2 Homology Domain-3 Mimetic GX15-070 Has Synergistic Antileukemia Activity by Activating Both Apoptosis and Autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659b5bfd22fae3c7c5cec87794edb435
https://doi.org/10.1158/1078-0432.22442588.v1
https://doi.org/10.1158/1078-0432.22442588.v1
Autor:
Guillermo Garcia-Manero, Susan O'Brien, Jean Viallet, Francesco Paolo Tambaro, Yumin Hu, Hui Yang, Yu Jia, Ming Zhang, Weigang Tong, Tapan Kadia, Yue Wei
Purpose: Single-agent histone deacetylase inhibitors (HDACi) have limited clinical activity in human leukemia. Although the way HDACi exert their antileukemia effect is not fully understood, it is accepted that induction of apoptosis is important. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9ea9599a7c586c65e04cff43f67d20
https://doi.org/10.1158/1078-0432.c.6519278.v1
https://doi.org/10.1158/1078-0432.c.6519278.v1
Autor:
John L. Marshall, Jean Viallet, Mark S. Berger, Lillian L. Siu, J.F. Deeken, Michael J. Pishvaian, David Mendelson, John Kuruvilla, Jimmy J. Hwang
Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a124712c97eaaacc7b5e00b86d2f5358
https://doi.org/10.1158/1078-0432.22442834
https://doi.org/10.1158/1078-0432.22442834
Autor:
John L. Marshall, Jean Viallet, Mark S. Berger, Lillian L. Siu, J.F. Deeken, Michael J. Pishvaian, David Mendelson, John Kuruvilla, Jimmy J. Hwang
Purpose: Two phase I, single-agent studies were conducted to determine the dose and regimen of obatoclax, an antagonist of all BCL-2 antiapoptotic proteins, for evaluation in phase II trials. The two studies, GX001 and GX005, evaluated the safety and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd7cac9cd54452ce63b1171daaaedfe
https://doi.org/10.1158/1078-0432.c.6519491
https://doi.org/10.1158/1078-0432.c.6519491
Autor:
Marc Billaud, Ruth Rimokh, Philippe Gonzalo, Germain Gillet, Cédric Hesling, Anaïs Girard-Gagnepain, Amandine Garcia, Jean Viallet, Rudy Gadet, Mouhannad Malek, Ivan Mikaelian
PDF file - 1195K, Supplementary Figure 4: RPTOR and mTOR silencing impair S6K phosphorylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d101c80691f9626a798fdad8905f9e
https://doi.org/10.1158/0008-5472.22400136.v1
https://doi.org/10.1158/0008-5472.22400136.v1
Autor:
Marc Billaud, Ruth Rimokh, Philippe Gonzalo, Germain Gillet, Cédric Hesling, Anaïs Girard-Gagnepain, Amandine Garcia, Jean Viallet, Rudy Gadet, Mouhannad Malek, Ivan Mikaelian
PDF file - 848K, Supplementary Figure 2: Inhibition of mTORC1 activates EMT and reduces cell proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd73793957ce6a6d5aa7691253c8106d
https://doi.org/10.1158/0008-5472.22400142.v1
https://doi.org/10.1158/0008-5472.22400142.v1
Autor:
Michael Andreeff, Ismael Samudio, Jean Viallet, Hagop Kantarjian, William Bornmann, Zeev Estrov, David Harris, Twee Tsao, Rooha Contractor, Julie Watt, Marina Konopleva
Supplementary Table 1 from Mechanisms of Antileukemic Activity of the Novel Bcl-2 Homology Domain-3 Mimetic GX15-070 (Obatoclax)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189463013f86011984d0f66405ee8208
https://doi.org/10.1158/0008-5472.22374401.v1
https://doi.org/10.1158/0008-5472.22374401.v1