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pro vyhledávání: '"Jean Vandaele"'
Autor:
Bernard Pipy, Jean Vandaele, Jacques Decerprit, Marie-Hélène Seguelas, Fabio Quartulli, Cécile Pollaud-Chérion
Publikováno v:
European Journal of Biochemistry. 253:345-353
We show that lipopolysaccharide-free actetylated low-density lipoprotein (LDL), but not native LDL, stimulates tumor-necrosis factor-alpha (TNF-alpha) secretion by rat peritoneal macrophages and the signal-transduction pathways involved. The role of
Autor:
Jean Vandaele, Olivier Meilhac, Isabelle Suc, Isabelle Lajoie-Mazenc, Günther Jürgens, Anne Nègre-Salvayre, Robert Salvayre
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 12(9)
Oxidized low density lipoproteins (oxLDL) are thought to play a major role in atherosclerosis. OxLDL exhibit a wide variety of biological effects resulting from their ability to interfere with intracellular signaling. The cellular targets and primary
Autor:
Alain Didier, Eric Pinelli, Marie C. Souqual, Bernard Pipy, Claudie Cambon, Jean Vandaele, Maryse Beraud, M. F. Forgue
Publikováno v:
Carcinogenesis. 12(3)
The effect of the carcinogen diethylnitrosamine (DEN) on prostaglandins (PGs), leukotrienes (LTs) and reactive oxygen intermediates production by murine peritoneal macrophages was assessed. In vitro exposure to DEN (0.8, 1.6 and 8 mM) resulted in a d