Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Jean Valmier"'
Autor:
Antoine Jouvenel, Adrien Tassou, Maxime Thouaye, Jérôme Ruel, Myriam Antri, Jean-Philippe Leyris, Aurore Giraudin, Sylvie Mallié, Chamroeum Sar, Lucie Diouloufet, Corinne Sonrier, François Daubeuf, Juliette Bertin, Stacy Alves, Stéphanie Ventéo, Nelly Frossard, Patrick Carroll, Ilana Mechaly, Didier Rognan, Pierre Sokoloff, Radhouane Dallel, Patrick Delmas, Jean Valmier, Cyril Rivat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Navigating the duality of opioids’ potent analgesia and side effects, including tolerance and hyperalgesia, is a significant challenge in chronic pain management, often prompting hazardous dose escalation to maintain analgesic effects. The
Externí odkaz:
https://doaj.org/article/62199c8ab61a47228dbb08f3a3507de8
Autor:
Cyril Rivat, Chamroeun Sar, Ilana Mechaly, Jean-Philippe Leyris, Lucie Diouloufet, Corinne Sonrier, Yann Philipson, Olivier Lucas, Sylvie Mallié, Antoine Jouvenel, Adrien Tassou, Henri Haton, Stéphanie Venteo, Jean-Philippe Pin, Eric Trinquet, Fabienne Charrier-Savournin, Alexandre Mezghrani, Willy Joly, Julie Mion, Martine Schmitt, Alexandre Pattyn, Frédéric Marmigère, Pierre Sokoloff, Patrick Carroll, Didier Rognan, Jean Valmier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Sensitisation of dorsal root ganglia neurons contributes to neuropathic pain. Here the authors demonstrate the cytokine FL contributes to sensitisation of DRGs via its receptor FLT3 expressed on neurons, and identify a novel FLT3 inhibitor that atten
Externí odkaz:
https://doaj.org/article/87fd7efd827f43ad990381c8a9541b42
Autor:
Fabrice Bouilloux, Jérôme Thireau, Stéphanie Ventéo, Charlotte Farah, Sarah Karam, Yves Dauvilliers, Jean Valmier, Neal G Copeland, Nancy A Jenkins, Sylvain Richard, Frédéric Marmigère
Publikováno v:
eLife, Vol 5 (2016)
Although cardio-vascular incidents and sudden cardiac death (SCD) are among the leading causes of premature death in the general population, the origins remain unidentified in many cases. Genome-wide association studies have identified Meis1 as a ris
Externí odkaz:
https://doaj.org/article/303724f029024de2813c23d49f828d6c
Autor:
Lucie Elzière, Chamroeun Sar, Stéphanie Ventéo, Steeve Bourane, Sylvie Puech, Corinne Sonrier, Hassan Boukhadaoui, Agnès Fichard, Alexandre Pattyn, Jean Valmier, Patrick Carroll, Ilana Méchaly
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97736 (2014)
Neurons innervating peripheral tissues display complex responses to peripheral nerve injury. These include the activation and suppression of a variety of signalling pathways that together influence regenerative growth and result in more or less succe
Externí odkaz:
https://doaj.org/article/c7945b53ad3147d290f4233dd9e44934
Autor:
Stéphanie Ventéo, Steeve Bourane, Ilana Méchaly, Chamroeun Sar, Omar Abdel Samad, Sylvie Puech, Rhoda Blostein, Jean Valmier, Alexandre Pattyn, Patrick Carroll
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29852 (2012)
Dorsal root ganglia (DRGs) contain the cell bodies of sensory neurons which relay nociceptive, thermoceptive, mechanoceptive and proprioceptive information from peripheral tissues toward the central nervous system. These neurons establish constant co
Externí odkaz:
https://doaj.org/article/65b5a13104ab470b8c0e897f8557c18c
Autor:
Govindan Dayanithi, Isabelle Richard, Cédric Viero, Elsa Mazuc, Sylvie Mallie, Jean Valmier, Nathalie Bourg, Muriel Herasse, Isabelle Marty, Gérard Lefranc, Paul Mangeat, Stephen Baghdiguian
Publikováno v:
International Journal of Cell Biology, Vol 2009 (2009)
Mutations of Ca2+-activated proteases (calpains) cause muscular dystrophies. Nevertheless, the specific role of calpains in Ca2+ signalling during the onset of dystrophies remains unclear. We investigated Ca2+ handling in skeletal cells from calpain
Externí odkaz:
https://doaj.org/article/f2d70311b13b470b8330f7dfe19dce4b
Autor:
Antoine Jouvenel, Adrien Tassou, Maxime Thouaye, Jérôme Ruel, Myriam Antri, Jean-Philippe Leyris, Aurore Paquet, Sylvie Mallié, Chamroeum Sar, Lucie Diouloufet, Corinne Sonrier, François Daubeuf, Juliette Bertin, Stacy Alves, Stéphanie Ventéo, Nelly Frossard, Patrick Carroll, Ilana Mechaly, Didier Rognan, Pierre Sokoloff, Radhouane Dallel, Patrick Delmas, Jean Valmier, Cyril Rivat
Opioid analgesia is counteracted on chronic use by tolerance and hyperalgesia inducing dose escalation and life-threatening overdoses. Mu opiate receptors (MOR) expressed in primary sensory neurons were recently found to control tolerance and hyperal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c8034c8ff982ad6b4eac00671207050
https://doi.org/10.1101/2023.03.16.532971
https://doi.org/10.1101/2023.03.16.532971
Autor:
Romain Hany, Jean-Philippe Leyris, Guillaume Bret, Sylvie Mallié, Chamroeun Sar, Maxime Thouaye, Abdallah Hamze, Olivier Provot, Pierre Sokoloff, Jean Valmier, Pascal Villa, Didier Rognan
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, 2022, 17 (3), pp.709-722. ⟨10.1021/acschembio.2c00048⟩
ACS Chemical Biology, 2022, 17 (3), pp.709-722. ⟨10.1021/acschembio.2c00048⟩
International audience; nhibiting receptor tyrosine kinases is commonly achieved by two main strategies targeting either the intracellular kinase domain by low molecular weight compounds or the extracellular ligand-binding domain by monoclonal antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41fdf03a3233fc02562674c1e8cbb35
https://doi.org/10.1021/acschembio.2c00048
https://doi.org/10.1021/acschembio.2c00048
Autor:
Adrien Tassou, Maxime Thouaye, Damien Gilabert, Antoine Jouvenel, Jean-Philippe Leyris, Corinne Sonrier, Lucie Diouloufet, Ilana Mechaly, Sylvie Mallié, Juliette Bertin, Myriam Chentouf, Madeline Neiveyans, Martine Pugnière, Pierre Martineau, Bruno Robert, Xavier Capdevila, Jean Valmier, Cyril Rivat
Publikováno v:
Progress in Neurobiology. 222:102405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e88c543a11f857603af25ec39ac7ee88
https://doi.org/10.1016/j.pneurobio.2023.102405
https://doi.org/10.1016/j.pneurobio.2023.102405
Autor:
Adrien Tassou, Maxime Thouaye, Damien Gilabert, Antoine Jouvenel, Jean-Philippe Leyris, Corinne Sonrier, Lucie Diouloufet, Ilana Mechaly, Sylvie Mallié, Myriam Chentouf, Madeline Neiveyans, Martine Pugnière, Pierre Martineau, Bruno Robert, Xavier Capdevila, Jean Valmier, Cyril Rivat
Acute pain events have been associated with persistent pain sensitization of nociceptive pathways increasing the risk of transition from acute to chronic pain. However, it is unclear whether injuryinduced persistent pain sensitization can promote lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8ad714faa248c39d306e759c51a3c2
https://doi.org/10.1101/2021.11.23.469557
https://doi.org/10.1101/2021.11.23.469557