Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Jean Sébastien Saulnier-Blache"'
Autor:
Aggeliki Tserga, Jean Sébastien Saulnier-Blache, Kostantinos Palamaris, Despoina Pouloudi, Harikleia Gakiopoulou, Jerome Zoidakis, Joost Peter Schanstra, Antonia Vlahou, Manousos Makridakis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1387 (2024)
Diabetic kidney disease (DKD) is characterized by histological changes including fibrosis and inflammation. Evidence supports that DKD is mediated by the innate immune system and more specifically by the complement system. Using Ins2Akita T1D diabeti
Externí odkaz:
https://doaj.org/article/43b763662a3a497fb6e5b5a434e854b9
Autor:
Aggeliki Tserga, Despoina Pouloudi, Jean Sébastien Saulnier-Blache, Rafael Stroggilos, Irene Theochari, Harikleia Gakiopoulou, Harald Mischak, Jerome Zoidakis, Joost Peter Schanstra, Antonia Vlahou, Manousos Makridakis
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 216 (2022)
Background: The absence of efficient inhibitors for diabetic kidney disease (DKD) progression reflects the gaps in our understanding of DKD molecular pathogenesis. Methods: A comprehensive proteomic analysis was performed on the glomeruli and kidney
Externí odkaz:
https://doaj.org/article/555b1d81e0914651a64ae5aec613a639
Publikováno v:
AIMS Molecular Science, Vol 3, Iss 2, Pp 222-237 (2016)
Lysophosphatidic acid (LPA) is a bioactive phospholipid that activates cell proliferation, differentiation and migration via the activation of its membrane-bound receptors (LPAR 1 to 6) expressed in various tissues and organs. Adipose tissue produces
Externí odkaz:
https://doaj.org/article/98ba2c069a054af1b8452ecd09594ec0
Autor:
Rodolphe Dusaulcy, Chloé Rancoule, Sandra Grès, Estelle Wanecq, André Colom, Charlotte Guigné, Laurens A. van Meeteren, Wouter H. Moolenaar, Philippe Valet, Jean Sébastien Saulnier-Blache
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 6, Pp 1247-1255 (2011)
Autotaxin (ATX) is a secreted lysophospholipase D that generates the lipid mediator lysophosphatidic acid (LPA). ATX is secreted by adipose tissue and its expression is enhanced in obese/insulin-resistant individuals. Here, we analyzed the specific c
Externí odkaz:
https://doaj.org/article/e5ac99397ff44ed8be0927e7dbf10e8b
Autor:
Stéphane Gesta, Marie-Françoise Simon, Astrid Rey, David Sibrac, Alexia Girard, Max Lafontan, Philippe Valet, Jean Sébastien Saulnier-Blache
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 904-910 (2002)
The aim of the present work was to depict the metabolic pathways involved in extracellular production of lysophosphatidic acid (LPA) by adipocytes. LPA was followed by quantifying the accumulation of LPA in the incubation medium (conditioned medium,
Externí odkaz:
https://doaj.org/article/85e54548da144661adb5aaf4643f922b
Autor:
Philippe Valet, Genevieéve Tavernier, Isabelle Castan-Laurell, Jean Sébastien Saulnier-Blache, Dominique Langin
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 835-860 (2002)
The World Health Organization has recognized obesity as a health problem of pandemic proportions. Recent work led to major breakthroughs in the understanding of the molecular basis of adipose tissue development with the cloning and characterization o
Externí odkaz:
https://doaj.org/article/708cddb37ce941e3a846f7bce1b1a57f
Autor:
Jean Sébastien Saulnier-Blache, Alexia Girard, Marie-Françoise Simon, Max Lafontan, Philippe Valet
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 12, Pp 1947-1951 (2000)
The objective of the present work was to develop a simple and sensitive radioenzymatic assay to quantify lysophosphatidic acid (LPA). For that, a recombinant rat LPA acid acyltransferase (LPAAT) produced in Escherichia coli was used. In the presence
Externí odkaz:
https://doaj.org/article/bff1e21728ab472dbe9237d5f85919cc
Autor:
Snigdha Rao, Audrey Casemayou, Marie Buleon, Guylene Feuillet, Elodie Riant, Alexia Zakaroff-Girard, Frédéric Martins, Ignacio Gonzalez-Fuentes, Jean Sébastien Saulnier Blache, Joost Schanstra, Julie Belliere
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Acute kidney injury (AKI) accounts for 13.3 million cases per year worldwide and further responsible for 1.7 million deaths per year [1]. Increasing incidence of AKI, progression toward CKD or end-stage renal disease (ESRD), affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7ea8bb09565a99879c7ba8d467a0a8
https://doi.org/10.1093/ndt/gfac067.077
https://doi.org/10.1093/ndt/gfac067.077
Autor:
Makridakis, Aggeliki Tserga, Despoina Pouloudi, Jean Sébastien Saulnier-Blache, Rafael Stroggilos, Irene Theochari, Harikleia Gakiopoulou, Harald Mischak, Jerome Zoidakis, Joost Peter Schanstra, Antonia Vlahou, Manousos
Publikováno v:
Biomedicines; Volume 10; Issue 2; Pages: 216
Background: The absence of efficient inhibitors for diabetic kidney disease (DKD) progression reflects the gaps in our understanding of DKD molecular pathogenesis. Methods: A comprehensive proteomic analysis was performed on the glomeruli and kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::162f80b7f5978d09641774884a9ee07c