Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean S. Oak"'
Autor:
Molly T. Radosevich, Scott J. Bornheimer, Majid Mehrpouryan, Bita Sahaf, Jean S. Oak, Crystal L. Mackall, Sabine Heitzeneder
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102709- (2023)
Summary: The central role of target antigen density on chimeric antigen receptor T cell potency highlights the need for accurate measurement of antigen levels on clinical tumor samples. Here, we present a protocol for quantifying antigen density for
Externí odkaz:
https://doaj.org/article/1ab2ce28e3a34b43a136e9f806598f43
Autor:
Jyoti Kumar, Vishesh Khanna, Rong Lu, Henning Stehr, Michael A Spinner, Oscar Silva, Sebastian Fernandez-Pol, Jean S Oak, Peter L Greenberg, Brent Tan
Publikováno v:
Blood. 140:4053-4055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0318918143f6ce7f1e570f8e51bfdf41
https://doi.org/10.1182/blood-2022-160237
https://doi.org/10.1182/blood-2022-160237
Autor:
Vishesh Khanna, Rong Lu, Jyoti Kumar, Henning Stehr, Michael A Spinner, Oscar Silva, Sebastian Fernandez-Pol, Jean S Oak, Brent Tan, Peter L Greenberg
Publikováno v:
Blood. 140:6955-6957
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368885dc62dd3bd28bf1fbd0c4e035d3
https://doi.org/10.1182/blood-2022-165841
https://doi.org/10.1182/blood-2022-165841
Autor:
Brian J. Sworder, David M. Kurtz, Stefan K. Alig, Matthew J. Frank, Navika Shukla, Andrea Garofalo, Charles W. Macaulay, Mohammad Shahrokh Esfahani, Mari N. Olsen, James Hamilton, Hitomi Hosoya, Mark Hamilton, Jay Y. Spiegel, John H. Baird, Takeshi Sugio, Mia Carleton, Alexander F.M. Craig, Sheren F. Younes, Bita Sahaf, Natasha D. Sheybani, Joseph G. Schroers-Martin, Chih Long Liu, Jean S. Oak, Michael C. Jin, Sara Beygi, Andreas Hüttmann, Christine Hanoun, Ulrich Dührsen, Jason R. Westin, Michael S. Khodadoust, Yasodha Natkunam, Robbie G. Majzner, Crystal L. Mackall, Maximilian Diehn, David B. Miklos, Ash A. Alizadeh
Publikováno v:
Cancer cell.
Most relapsed/refractory large B cell lymphoma (r/rLBCL) patients receiving anti-CD19 chimeric antigen receptor (CAR19) T cells relapse. To characterize determinants of resistance, we profiled over 700 longitudinal specimens from two independent coho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee704aa72f5524de499026f0629eeb9
https://pubmed.ncbi.nlm.nih.gov/36584673
https://pubmed.ncbi.nlm.nih.gov/36584673
Autor:
Hrishikesh K. Srinagesh, John Baird, Shabnum Patel, Agnes Reschke, Juliana Craig, Jay Spiegel, Sushma Bharadwaj, Zachary Ehlinger, Harshini Chinnasamy, Sheren F. Younes, Jean S. Oak, Yasodha Natkunam, Warren D. Reynolds, Maria Iglesias, Emma Crawford, Emily Egeler, Liora Michal Schultz, Sneha Ramakrishna, Kara L Davis, Bita Sahaf, Steven Feldman, Crystal Mackall, David B. Miklos, Lori Muffly, Matthew J. Frank
Publikováno v:
Transplantation and Cellular Therapy. 28:S162-S163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90da7a59f30517d1ac543aa44ba0d3b5
https://doi.org/10.1016/s2666-6367(22)00359-1
https://doi.org/10.1016/s2666-6367(22)00359-1
Autor:
Jean S. Oak, Rosemarie H. DeKruyff, Anjali J. de Souza, Lawrence P. Kane, Ryan Jordanhazy, David A. Fruman
Publikováno v:
The Journal of Immunology. 180:6518-6526
Ligation of the transmembrane protein T cell Ig and mucin domain (Tim)-1 can costimulate T cell activation. Agonistic Abs to Tim-1 are also capable of inducing T cell activation without additional stimuli. However, little is known about the biochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36b73124cdcd1aa58ec9967c8944635
https://doi.org/10.4049/jimmunol.180.10.6518
https://doi.org/10.4049/jimmunol.180.10.6518
Autor:
Catherine Li, Lakshmi Ganesan, David Sept, Susan Tsai, Christopher I. Ma, Jean S. Oak, Naomi S. Morrissette
Publikováno v:
Molecular Biology of the Cell. 18:4711-4720
Protozoan microtubules are sensitive to disruption by dinitroanilines, compounds that kill intracellular Toxoplasma gondii parasites without affecting microtubules in vertebrate host cells. We previously isolated a number of resistant Toxoplasma line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69997f9642cdccb7e873d7eb0ac95b31
https://doi.org/10.1091/mbc.e07-04-0379
https://doi.org/10.1091/mbc.e07-04-0379
Autor:
Jean S. Oak, David A. Fruman
Publikováno v:
Autoimmunity. 40:433-441
Activation of the phosphoinositide 3-kinase (PI3K) pathway promotes proliferation and survival in many different cell types of the immune system. PI3K acts downstream of receptors that mediate proliferation and survival in T cells, and required roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7ac344c02058fb6296b2acbf31cb56
https://doi.org/10.1080/08916930701464780
https://doi.org/10.1080/08916930701464780
Autor:
Jonathan A. Deane, Jean S. Oak, Thomas E. Lane, Travis I. Moore, Linda N. Stiles, Lewis C. Cantley, Ji Luo, Michael G. Kharas, Hong Ji, David A. Fruman, Christian Rommel
Publikováno v:
Blood
The class IA subgroup of phosphoinositide 3-kinase (PI3K) is activated downstream of antigen receptors, costimulatory molecules, and cytokine receptors on lymphocytes. Targeted deletion of individual genes for class IA regulatory subunits severely im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea68c3392fcece1b849599777d91d45
https://doi.org/10.1182/blood-2006-07-038620
https://doi.org/10.1182/blood-2006-07-038620
Autor:
Lewis C. Cantley, David A. Fruman, Thomas E. Lane, Michael G. Kharas, Ji Luo, Jean S. Oak, Jonathan A. Deane
Publikováno v:
Proceedings of the National Academy of Sciences. 103:16882-16887
Sjögren's syndrome (SS) is an autoimmune disease that is characterized by infiltration of exocrine tissues, resulting in xerostomia (dry mouth) and keratoconjunctivitis sicca (dry eyes). Here, we show that mice with T cell-specific loss of class IA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abccb8fa9d921576e776466d3f278975
https://doi.org/10.1073/pnas.0607984103
https://doi.org/10.1073/pnas.0607984103