Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jean S. Kahan"'
Autor:
Thomas N. Salzmann, Jean S. Kahan, Frank P. DiNinno, Joann Huber, David A. Muthard, Helmut Kropp
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:945-948
The discovery and synthesis of the arylcarbapenem 2b possessing potent activity against highly resistant strains of methicillin resistant staphylococci are dislosed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f5a88691499395fd1cb8d0b4d959eb2
https://doi.org/10.1016/0960-894x(95)00149-n
https://doi.org/10.1016/0960-894x(95)00149-n
Autor:
Thomas N. Salzmann, Frank P. DiNinno, Helmut Kropp, Joann Huber, David A. Muthard, Jean S. Kahan
Publikováno v:
ChemInform. 26
The discovery and synthesis of the arylcarbapenem 2b possessing potent activity against highly resistant strains of methicillin resistant staphylococci are dislosed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b925c1defd4c6a99d468b1d05c1b1b
https://doi.org/10.1002/chin.199537276
https://doi.org/10.1002/chin.199537276
Publikováno v:
Antimicrobial Agents and Chemotherapy. 17:993-1000
The practical application of thienamycin, a novel beta-lactam antibiotic with a broad activity spectrum, was compromised by problems of instability. MK0787, N-formimidoyl thienamycin, does not have this liability. As reported, bacterial species resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26fdf6f46ec597d70dd0f0708dc8636
https://doi.org/10.1128/aac.17.6.993
https://doi.org/10.1128/aac.17.6.993
Autor:
Karst Hoogsteen, Frederick M. Kahan, Jean S. Kahan, Robert E. Rhodes, Byron H. Arison, G. Albers-Schoenberg, J. Hirshfield, Otto D. Hensens, Edward A. Kaczka
Publikováno v:
Journal of the American Chemical Society. 100:6491-6499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3132e06046f741efd6e037faf5110de8
https://doi.org/10.1021/ja00488a038
https://doi.org/10.1021/ja00488a038
Autor:
K. Alestig, Jean S. Kahan, S R Norrby, Jon G. Sundelof, Joann Huber, Helmut Kropp, Frederick M. Kahan, M. A. P. Meisinger, L. A. Burman, B. Björnegård, K. H. Jones, F. Ferber
Publikováno v:
Antimicrobial Agents and Chemotherapy. 23:300-307
N -Formimidoyl thienamycin (MK0787) undergoes renal metabolism by a dipeptidase, dehydropeptidase I, located on the brush border of the proximal tubular cells. The effects of two inhibitors (MK-789 and MK-791) of dehydropeptidase I on the pharmacokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d299a7f33e6ab81cf74097a86ce3df35
https://doi.org/10.1128/aac.23.2.300
https://doi.org/10.1128/aac.23.2.300
Autor:
Robert T. Goegelman, David Hendlin, Edward O. Stapley, M. Jackson, Sagrario Mochales, Frederick M. Kahan, Thomas W. Miller, Jean S. Kahan, Sara A. Currie, Jerome Birnbaum, Miller Ak, H. B. Woodruff, Sebastian Hernandez
Publikováno v:
The Journal of Antibiotics. 32:1-12
A new beta-lactam antibiotic, named thienamycin, was discovered in culture broths of Streptomyces MA4297. The producing organism, subsequently determined to be a hitherto unrecognized species, is designated Streptomyces cattleya (NRRL 8057). The anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dfb0b4219a6b61aea86c4c92ec7ace
https://doi.org/10.7164/antibiotics.32.1
https://doi.org/10.7164/antibiotics.32.1
Publikováno v:
Annals of the New York Academy of Sciences. 235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9223328988d862460c2cd535d91c262
https://pubmed.ncbi.nlm.nih.gov/4605290
https://pubmed.ncbi.nlm.nih.gov/4605290