Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jean Sébastien Brunet"'
Autor:
W. Glenn McCluggage, Heather E. Cunliffe, Michel Longy, Andrew Berchuck, Anthony N. Karnezis, Catherine Goudie, Jeffrey M. Trent, Talia Boshari, Emmanouil Saloustros, Jean Sébastien Brunet, Douglas A. Levine, Leora Witkowski, David G. Huntsman, William D. Foulkes, William P.D. Hendricks, Patricia Pautier, Colin J.R. Stewart, James A. Knost, Martin Hasselblatt, Pilar Ramos
Publikováno v:
Gynecologic oncology, vol 141, iss 3
OBJECTIVE: Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is an aggressive tumor, with long term survival at ~30% in early stage disease. SCCOHT is caused by germline and somatic SMARCA4 mutations, but the effect of the mutation type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55e10a3a7a1bc1d89b3a2e697f49021
https://europepmc.org/articles/PMC6876126/
https://europepmc.org/articles/PMC6876126/
Autor:
Yury Monczak, Lidia Kasprzak, Jean Latreille, Sonya Zaor, Rachel Laframboise, Bruno Maranda, Marc Tischkowitz, William D. Foulkes, Nora Wong, George Chong, Carole Richard, Mona Kay Wu, Jean Gekas, Carly Pouchet, Jonathan Jarry, Régen Drouin, Laura Palma, Jean-Sébastien Brunet
Publikováno v:
Familial Cancer. 10:659-665
This is an 11-year survey of molecular analysis of APC germline mutations for the province of Quebec done at the Molecular Pathology Unit of the Jewish General Hospital which offers genetic testing for hereditary forms of colorectal cancer for the wh
Autor:
Marc Lefebvre, Michael Grace, Jean-Sébastien Brunet, Jean Spénard, Christian Aumais, Julie Massicotte, Claude Tremblay
Publikováno v:
British Journal of Clinical Pharmacology. 60:374-377
Aims To evaluate the effects of food and formulation on the pharmacokinetics of bismuth biskalcitrate, metronidazole and tetracycline when combined in a new 3-in-1 single capsule (BMT) for eradication of Helicobacter pylori. Methods In a randomized,
Autor:
Jarle B. Arnes, Ingunn M. Stefansson, Pierre O. Chappuis, Jean-Sébastien Brunet, William D. Foulkes, Louis R. Bégin, Lars A. Akslen, Nora Wong
Publikováno v:
Clinical Cancer Research. 11:4003-4011
Purpose: BRCA1-related breast cancer frequently has a basal epithelial phenotype, and P-cadherin is a basal marker. We undertook a detailed evaluation of the relationship among P-cadherin, prognostic markers in breast cancer, and outcome. Experimenta
Autor:
Peggy L. Porter, Oddbjørn Straume, Linda Kapusta, John R. Goffin, William D. Foulkes, Lars A. Akslen, Nora Wong, Ingunn M. Stefansson, Louis R. Bégin, Michel Trudel, Jean-Sébastien Brunet, Pierre O. Chappuis, Nancy Hamel
Publikováno v:
Cancer Research. 64:830-835
Previous studies have shown that BRCA1-related breast cancers are often high-grade tumors that do not express estrogen receptors, HER2, p27Kip1, or cyclin D1, but do express p53 and cyclin E. In addition, the expression of cytokeratin 5/6 (CK5/6), in
Autor:
Nadine Tung, Louis R. Bégin, Kelly A. Metcalfe, Barbara L. Weber, Parviz Ghadirian, Ivo A. Olivotto, Pierre O. Chappuis, Jane McLennan, Wedad Hanna, William D. Foulkes, O. I. Olopade, Steven A. Narod, Ping Sun, Jean Sébastien Brunet, Henry T. Lynch
Publikováno v:
Cancer. 98:1569-1577
BACKGROUND A positive correlation between breast tumor size and the number of axillary lymph nodes containing tumor is well established. It has been reported that patients with BRCA1-related breast carcinoma are more likely than patients with nonhere
Autor:
Barbara L. Weber, Steven A. Narod, Jean Sébastien Brunet, Patricia De Los Rios, Dominique Stoppa-Lyonnet, Susan L. Neuhausen, Caryn Lerman, Mark E. Robson, Ketil Heimdal, Henry T. Lynch, Parviz Ghadirian, Barbara Pasini
Publikováno v:
The Lancet. 356:1876-1881
Summary Background Women with a mutation in BRCA1 or BRCA2 have a high risk of developing breast cancer and of contralateral cancer after the initial diagnosis of breast cancer. Tamoxifen protects against contralateral breast cancer in the general po
Autor:
Parviz Ghadirian, Jean-Sébastien Brunet, Annick Wong Wong Keet, Munir Al‐Rafae, Pierre O. Chappuis, William D. Foulkes
Publikováno v:
International Journal of Cancer. 125:2236-2238
Autor:
Helena Jernström, M. Daly, Olufunmilayo I. Olopade, Parviz Ghadirian, Judy Garber, Ellen Warner, Steven A. Narod, Caryn Lerman, Jean-Sébastien Brunet, William D. Foulkes, Henry T. Lynch, Barbara L. Weber
Publikováno v:
The Lancet. 354:1846-1850
Summary Background Early age at first full-term pregnancy and increasing parity are associated with a reduced risk of breast cancer. However, whether pregnancy decreases the risk of early-onset hereditary breast cancer is unknown. There is concern th
Autor:
Philip H. Gordon, Louis R. Bégin, Leonard Pinsky, William D. Foulkes, Jean Sébastien Brunet, Zhi Qiang Yuan, Mark Trifiro, Nora Wong
Publikováno v:
British Journal of Cancer
The I1307K polymorphism in APC has been found to predispose to colorectal cancer in Ashkenazi Jews, and has recently been associated with an increased risk for breast cancer in the same population. In that study, we genotyped 205 paraffin-embedded br