Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Jean Rommelaere"'
Publikováno v:
Cancers, Vol 16, Iss 15, p 2711 (2024)
The rat protoparvovirus H-1 (H-1PV) is an oncolytic virus known for its anticancer properties in laboratory models of various human tumors, including non-Hodgkin lymphomas (NHL) of B-cell origin. However, H-1PV therapeutic potential against hematolog
Externí odkaz:
https://doaj.org/article/b8c40e2fbc5a4055b0753823bf5c3b36
Publikováno v:
Pathogens, Vol 13, Iss 3, p 184 (2024)
Cutaneous T-cell lymphoma (CTCL) is a devastating, potentially fatal T-lymphocyte malignancy affecting the skin. Despite all efforts, the etiology of this disease remains unknown. Infectious agents have long been suspected as factors or co-factors in
Externí odkaz:
https://doaj.org/article/4bfc9bad9ef74132b23a5db35528634c
Autor:
Assia Angelova, Kristina Pierrard, Claudia N. Detje, Estelle Santiago, Annabel Grewenig, Jürg P. F. Nüesch, Ulrich Kalinke, Guy Ungerechts, Jean Rommelaere, Laurent Daeffler
Publikováno v:
Pathogens, Vol 12, Iss 4, p 607 (2023)
The oncolytic rodent protoparvoviruses (PVs) minute virus of mice (MVMp) and H-1 parvovirus (H-1PV) are promising cancer viro-immunotherapy candidates capable of both exhibiting direct oncolytic activities and inducing anticancer immune responses (AI
Externí odkaz:
https://doaj.org/article/0cec5c2ad0b44c5ea20d93741c866e53
Autor:
Claudia Tessmer, Claudia Plotzky, Jana Fees, Hendrik Welsch, Rebecca Eudenbach, Martin Faber, Alicia Simón, Assia Angelova, Jean Rommelaere, Ilse Hofmann, Jürg P. F. Nüesch
Publikováno v:
Pathogens, Vol 11, Iss 2, p 208 (2022)
For many applications it is necessary to detect target proteins in living cells. This is particularly the case when monitoring viral infections, in which the presence (or absence) of distinct target polypeptides potentially provides vital information
Externí odkaz:
https://doaj.org/article/90a6a548d8844de2bc2259e951369e22
Autor:
Dirk M. Nettelbeck, Mathias F. Leber, Jennifer Altomonte, Assia Angelova, Julia Beil, Susanne Berchtold, Maike Delic, Jürgen Eberle, Anja Ehrhardt, Christine E. Engeland, Henry Fechner, Karsten Geletneky, Katrin Goepfert, Per Sonne Holm, Stefan Kochanek, Florian Kreppel, Lea Krutzke, Florian Kühnel, Karl Sebastian Lang, Antonio Marchini, Markus Moehler, Michael D. Mühlebach, Ulrike Naumann, Roman Nawroth, Jürg Nüesch, Jean Rommelaere, Ulrich M. Lauer, Guy Ungerechts
Publikováno v:
Viruses, Vol 13, Iss 8, p 1420 (2021)
Virotherapy research involves the development, exploration, and application of oncolytic viruses that combine direct killing of cancer cells by viral infection, replication, and spread (oncolysis) with indirect killing by induction of anti-tumor immu
Externí odkaz:
https://doaj.org/article/2afbc836e8844aa9a40984a8fca1af73
Autor:
Jacek Hajda, Monika Lehmann, Ottheinz Krebs, Meinhard Kieser, Karsten Geletneky, Dirk Jäger, Michael Dahm, Bernard Huber, Tilman Schöning, Oliver Sedlaczek, Albrecht Stenzinger, Niels Halama, Volker Daniel, Barbara Leuchs, Assia Angelova, Jean Rommelaere, Christine E. Engeland, Christoph Springfeld, Guy Ungerechts
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Metastatic pancreatic cancer has a dismal prognosis, with a mean six-month progression-free survival of approximately 50% and a median survival of about 11 months. Despite intensive research, only slight improvements of clinical o
Externí odkaz:
https://doaj.org/article/18ddc49db19048d6bab8de3a50b57f70
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cancer cells utilize multiple mechanisms to evade and suppress anticancer immune responses creating a “cold” immunosuppressive tumor microenvironment. Oncolytic virotherapy is emerging as a promising approach to revert tumor immunosuppression and
Externí odkaz:
https://doaj.org/article/af6af5f5c2824bd4b6548390261ad199
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The recent therapeutic success of immune checkpoint inhibitors in the treatment of advanced melanoma highlights the potential of cancer immunotherapy. Oncolytic virus-based therapies may further improve the outcome of these cancer patients. A human e
Externí odkaz:
https://doaj.org/article/bdbc7baba506468597e8fc78f4ede9e0
Publikováno v:
Cancers, Vol 13, Iss 2, p 342 (2021)
Resistance to anticancer treatments poses continuing challenges to oncology researchers and clinicians. The underlying mechanisms are complex and multifactorial. However, the immunologically “cold” tumor microenvironment (TME) has recently emerge
Externí odkaz:
https://doaj.org/article/a39522939110447a91131aca77d8f02e
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Non-Hodgkin lymphoma (NHL) and leukemia are among the most common cancers worldwide. While the treatment of NHL/leukemia of B-cell origin has much progressed with the introduction of targeted therapies, few treatment standards have been established f
Externí odkaz:
https://doaj.org/article/b4414111e8904d44bb27cca2afe89ed8