Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Jean Pierre Salles"'
Autor:
Coline Rouleau, Margaux Malorie, Corinne Collet, Valérie Porquet-Bordes, Isabelle Gennero, Sanaa Eddiry, Michel Laroche, Jean Pierre Salles, Guillaume Couture, Thomas Edouard
Publikováno v:
Bone Reports, Vol 16, Iss , Pp 101176- (2022)
Aim: To describe the presenting features, bone characteristics and molecular genetics in a large monocentric cohort of children and young adults with idiopathic primary osteoporosis. Methods: Sixty-six patients (19 children, 47 adults; 28 males, 38 f
Externí odkaz:
https://doaj.org/article/da53931ce1f04fc39360489f39780b7d
Autor:
Ravi Savarirayan, Josep Maria De Bergua, Paul Arundel, Helen McDevitt, Valerie Cormier-Daire, Vrinda Saraff, Mars Skae, Borja Delgado, Antonio Leiva-Gea, Fernando Santos-Simarro, Jean Pierre Salles, Marc Nicolino, Massimiliano Rossi, Peter Kannu, Michael B. Bober, John Phillips, Howard Saal, Paul Harmatz, Christine Burren, Garrett Gotway, Terry Cho, Elena Muslimova, Richard Weng, Daniela Rogoff, Julie Hoover-Fong, Melita Irving
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 14 (2022)
Background: Achondroplasia is the most common short-limbed skeletal dysplasia resulting from gain-of-function pathogenic variants in fibroblast growth factor receptor 3 ( FGFR3 ) gene, a negative regulator of endochondral bone formation. Most treatme
Externí odkaz:
https://doaj.org/article/1c346c9389564e0d8a57401f2309d651
Autor:
Michel Laroche, Guillaume Couture, Marie Faruch, Adeline Ruyssen‐Witrand, Valérie Porquet‐Bordes, Jean Pierre Salles, Yannick Degboe
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
ABSTRACT Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in children, whereas bone remodeling is different between t
Externí odkaz:
https://doaj.org/article/2b8e77ffd98546fbac9f4f8adfeaeef8
Autor:
Ronan Barre, Nicolas Beton, Aurélie Batut, Frank Accabled, Jerome Sales de Gauzy, Françoise Auriol, Sanaa Eddiry, Maithe Tauber, Sara Laurencin, Jean Pierre Salles, Isabelle Gennero
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100782- (2020)
We have examined the Acylated Ghrelin (AG)/Gi pathway in different human osteoblastic cell lines. We have found that: 1) AG induces differentiation/mineralization only in mature osteoblasts; 2) the expression of GHS-R1a increases up to the mature cel
Externí odkaz:
https://doaj.org/article/6ea7d449ef3444328547430fe9d5b148
Autor:
Fabienne Briand-Mésange, Isabelle Gennero, Juliette Salles, Stéphanie Trudel, Lionel Dahan, Jérôme Ausseil, Bernard Payrastre, Jean-Pierre Salles, Hugues Chap
Publikováno v:
Molecules, Vol 29, Iss 15, p 3694 (2024)
2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in postsynaptic membranes through the sequential action of phosphoinositide-speci
Externí odkaz:
https://doaj.org/article/9abc783c17c548a88592a6d84b2648a0
Autor:
Alice Broutin, Jean-Pierre Salles, Valérie Porquet-Bordes, Thomas Edouard, Frédéric Vaysse, Emmanuelle Noirrit-Esclassan
Publikováno v:
Children, Vol 11, Iss 8, p 900 (2024)
Background/Objectives: Osteogenesis imperfecta (OI) is a rare genetic disease that is responsible for bone fragility, but also for dental malocclusions and dentinogenesis imperfecta (DI). The aim of this study was to assess whether the severity of de
Externí odkaz:
https://doaj.org/article/772566aa0f7048edbae2935e08cc5f8e
Publikováno v:
Hormone Research in Paediatrics.
Introduction Growth hormone (GH) therapy improves height outcomes in short children born small for gestational age (SGA); however, real-world data on long-term GH exposure are few. Methods We report results from an observational study (NCT01578135) i
Autor:
Caroline Caetano da Silva, Thomas Edouard, Melanie Fradin, Marion Aubert-Mucca, Manon Ricquebourg, Ratish Raman, Jean Pierre Salles, Valérie Charon, Pascal Guggenbuhl, Marc Muller, Martine Cohen-Solal, Corinne Collet
Publikováno v:
Human Molecular Genetics
Monogenic early onset osteoporosis (EOOP) is a rare disease defined by low bone mineral density (BMD) that results in increased risk of fracture in children and young adults. Although several causative genes have been identified, some of the EOOP cau
Autor:
Celine Saint-Laurent, Stephanie Garcia, Vincent Sarrazy, Karine Dumas, Florence Authier, Sophie Sore, Albert Tran, Philippe Gual, Isabelle Gennero, Jean-Pierre Salles, Elvire Gouze
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195876 (2018)
Achondroplasia is a rare genetic disease is characterized by abnormal bone development and early obesity. While the bone aspect of the disease has been thoroughly studied, early obesity affecting approximately 50% of them during childhood has been so
Externí odkaz:
https://doaj.org/article/35dc66f3290840868b6ce19b5ac9a2cd
Autor:
Julie Bernardor, Sacha Flammier, Jean-Pierre Salles, Cyril Amouroux, Mireille Castanet, Anne Lienhardt, Laetitia Martinerie, Ivan Damgov, Agnès Linglart, Justine Bacchetta
Publikováno v:
Frontiers in Pediatrics. 10
BackgroundCinacalcet is a calcimimetic approved in adults with primary hyperparathyroidism (PHPT). Few cases reports described its use in pediatric HPT, with challenges related to the risk of hypocalcemia, increased QT interval and drug interactions.