Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jean Pierre Haelters"'
Autor:
Christophe Vandier, Philippe Bougnoux, Virginie Joulin, Pierre Besson, Michelle Pinault, Paul-Alain Jaffrès, Jean-Pierre Haelters, Flavie Arbion, Alban Girault, Thibauld Oullier, Christine Collin, Jean-Christophe Pagès, Maxime Guéguinou, Séverine Marionneau-Lambot, Gaëlle Fromont, Lucie Clarysse, Marie Potier-Cartereau, Aurélie Chantôme
PDF file - 579K, S1. Validation of the MDA-MB-435s cell system expressing luciferase gene and expressing or not KCNN3 gene. S2. SK3 knockdown reduced the development of metastases in cancer cell xenograft models. A) SK3 knockdown reduced the metastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d555adbcffe04e87d3b59d34a2c8cc68
https://doi.org/10.1158/0008-5472.22396100.v1
https://doi.org/10.1158/0008-5472.22396100.v1
Autor:
Christophe Vandier, Philippe Bougnoux, Virginie Joulin, Pierre Besson, Michelle Pinault, Paul-Alain Jaffrès, Jean-Pierre Haelters, Flavie Arbion, Alban Girault, Thibauld Oullier, Christine Collin, Jean-Christophe Pagès, Maxime Guéguinou, Séverine Marionneau-Lambot, Gaëlle Fromont, Lucie Clarysse, Marie Potier-Cartereau, Aurélie Chantôme
PDF file - 128K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419d6bb2ca7b9477cd7f1305f0513713
https://doi.org/10.1158/0008-5472.22396097.v1
https://doi.org/10.1158/0008-5472.22396097.v1
Autor:
Nawal Belmadi, Mathieu Berchel, Caroline Denis, Wilfried Berthe, Yann Sibiril, Tony Le Gall, Jean-Pierre Haelters, Paul-Alain Jaffres, Tristan Montier
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 26055-26076 (2015)
The objective of lung gene therapy is to reach the respiratory epithelial cells in order to deliver a functional nucleic acid sequence. To improve the synthetic carrier’s efficacy, knowledge of their biodistribution and elimination pathways, as wel
Externí odkaz:
https://doaj.org/article/eb7e0e25c93e497ea3e23d0063cc6863
Autor:
Stéphanie S. Le Corre, Mathieu Berchel, Hélène Couthon-Gourvès, Jean-Pierre Haelters, Paul-Alain Jaffrès
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 1166-1196 (2014)
Initially, the Atherton–Todd (AT) reaction was applied for the synthesis of phosphoramidates by reacting dialkyl phosphite with a primary amine in the presence of carbon tetrachloride. These reaction conditions were subsequently modified with the a
Externí odkaz:
https://doaj.org/article/b8d7281fe58d484ab04496faf48daadd
Autor:
Audrey Gambade, Marie Potier-Cartereau, Yann Fourbon, Philippe Bougnoux, Romain Félix, Sana Kouba, David Ternant, François Carreaux, Maxime Guéguinou, Ana Bouchet, Paul-Alain Jaffrès, Thomas Harnois, Christophe Vandier, Olivier Mignen, Aurélie Chantôme, Christophe Arnoult, Jean-Pierre Haelters, Thibauld Oullier, Séverine Marionneau-Lambot, Aubin Penna, Günther Weber, Gaëlle Simon
Publikováno v:
Cell Calcium
Cell Calcium, 2021, 97, pp.102435. ⟨10.1016/j.ceca.2021.102435⟩
Cell Calcium, Elsevier, 2021, 97, pp.102435. ⟨10.1016/j.ceca.2021.102435⟩
Cell Calcium, 2021, 97, pp.102435. ⟨10.1016/j.ceca.2021.102435⟩
Cell Calcium, Elsevier, 2021, 97, pp.102435. ⟨10.1016/j.ceca.2021.102435⟩
International audience; The Transient Receptor Potential Vanilloid type 2 (TRPV2) channel is highly selective for Ca2+ and can be activated by lipids, such as LysoPhosphatidylCholine (LPC). LPC analogues, such as the synthetic alkyl-ether-lipid edelf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b589885907e9b5087bfabdb1931bc63
https://hal.univ-brest.fr/hal-03278876
https://hal.univ-brest.fr/hal-03278876
Autor:
Olivier Lozach, Tristan Montier, Jean-Pierre Haelters, Mathieu Berchel, Tony Le Gall, Paul-Alain Jaffrès
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2016, 14 (10), pp.2846-2853. ⟨10.1039/C5OB02512E⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2016, 14 (10), pp.2846-2853. ⟨10.1039/C5OB02512E⟩
International audience; Six new cationic bolaamphiphiles (also called bipolar amphiphiles, bolaform amphiphiles, or bolalipids) were readily prepared by a thiol–ene click reaction that engaged a mercapto-alcohol (mercapto-ethanol or mercapto-hexano
Autor:
Paul-Alain Jaffrès, Pierre Lehn, Jean-Pierre Haelters, Mathieu Berchel, Tristan Montier, Tony Le Gall
Publikováno v:
Molecular Pharmaceutics
Molecular Pharmaceutics, American Chemical Society, 2015, 12 (6), pp.1902-1910. ⟨10.1021/mp500807k⟩
Molecular Pharmaceutics, American Chemical Society, 2015, 12 (6), pp.1902-1910. ⟨10.1021/mp500807k⟩
International audience; The structure of the cationic moiety of amphiphiles is a key factor which directly influences their transfection efficacy. Accordingly, in the present work, we have synthesized three new lipophosphoramide-based amphiphilic com
Autor:
Nawal Belmadi, Pierre Lehn, Tony Le Gall, Stéphanie S. Le Corre, Jean-Pierre Haelters, Paul-Alain Jaffrès, Tristan Montier, Mathieu Berchel
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2015, 13 (4), pp.1122-1132. ⟨10.1039/C4OB01770F⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2015, 13 (4), pp.1122-1132. ⟨10.1039/C4OB01770F⟩
International audience; In this work that aims to synthesize and evaluate new cationic lipids as vectors for gene delivery, we report the synthesis of a series of cationic lipids in which a phosphate functional group acts as a linker to assemble on a
Autor:
Tristan Montier, Paul-Alain Jaffrès, Stéphanie S. Le Corre, Mathieu Berchel, Pierre Lehn, Tony Le Gall, Jean-Pierre Haelters
Publikováno v:
European Journal of Organic Chemistry. 2014:8041-8048
We report herein the synthesis of a novel family of cationic lipids, characterized by a trimethylammonium headgroup linked through a phosphate function to either two identical or two different lipid chains. The novelty of this study arises from the u
Autor:
Nawal Belmadi, Stéphanie S. Le Corre, Paul-Alain Jaffrès, Tony Le Gall, Caroline Denis, Tristan Montier, Pierre Lehn, Jean-Pierre Haelters, Mathieu Berchel
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2013, 12 (9), ⟨10.1039/C3OB42270D⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2013, 12 (9), ⟨10.1039/C3OB42270D⟩
International audience; Cationic lipids constitute a family of synthetic vectors commonly used for nucleic acids delivery. We herein report the results of a systematic study that aimed to compare the transfection efficacies of cationic lipophosphoram