Zobrazeno 1 - 10 of 30 pro vyhledávání: '"Jean Pierre Grill"'
1
Akademický článek
Urbanization associates with restricted gut microbiome diversity and delayed maturation in infants
Autor: Francesco Morandini, Kevin Perez, Loic Brot, Sidy Mohammed Seck, Laurence Tibère, Jean-Pierre Grill, Enguerran Macia, Philippe Seksik
Publikováno v: iScience, Vol 26, Iss 11, Pp 108136- (2023)
Summary: Alterations of the microbiome are linked to increasingly common diseases such as obesity, allergy, and inflammatory bowel disease. Post-industrial lifestyles are thought to contribute to the gut microbiome alterations that cause or aggravate
Externí odkaz: https://doaj.org/article/23d57441423145359e970fb4e067949f
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2
Akademický článek
3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors
Autor: Garance Coquant, Doriane Aguanno, Loïc Brot, Christine Belloir, Julie Delugeard, Nathalie Roger, Hang-Phuong Pham, Loïc Briand, Marielle Moreau, Luisa de Sordi, Véronique Carrière, Jean-Pierre Grill, Sophie Thenet, Philippe Seksik
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule 3-oxo-C12:2-HSL, first identified in human gut microbiota, exerts anti-inflammatory
Externí odkaz: https://doaj.org/article/b8792f0195a14d089cac4c1d13deb817
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3
Akademický článek
Impact of IBD-Associated Dysbiosis on Bacterial Quorum Sensing Mediated by Acyl-Homoserine Lactone in Human Gut Microbiota
Autor: Nathan Grellier, Marcelino T. Suzuki, Loic Brot, Alice M. S. Rodrigues, Lydie Humbert, Karine Escoubeyrou, Dominique Rainteau, Jean-Pierre Grill, Raphaël Lami, Philippe Seksik
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 23, p 15404 (2022)
Intestinal dysbiosis is a key feature in the pathogenesis of inflammatory bowel disease (IBD). Acyl-homoserine lactones (AHL) are bacterial quorum-sensing metabolites that may play a role in the changes in host cells-gut microbiota interaction observ
Externí odkaz: https://doaj.org/article/3a67ba09e8aa4540b3e1a090145281bb
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4
Akademický článek
Impact of N-Acyl-Homoserine Lactones, Quorum Sensing Molecules, on Gut Immunity
Autor: Garance Coquant, Jean-Pierre Grill, Philippe Seksik
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Among numerous molecules found in the gut ecosystem, quorum sensing (QS) molecules represent an overlooked part that warrants highlighting. QS relies on the release of small molecules (auto-inducers) by bacteria that accumulate in the environment dep
Externí odkaz: https://doaj.org/article/b5e455d1c375409fa392b7ac42ef3b1d
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5
Akademický článek
Anti-Inflammatory Effects of Analogues of N-Acyl Homoserine Lactones on Eukaryotic Cells
Autor: Agathe Peyrottes, Garance Coquant, Loïc Brot, Dominique Rainteau, Philippe Seksik, Jean-Pierre Grill, Jean-Maurice Mallet
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 24, p 9448 (2020)
Background: Since acyl-homoserine lactone (AHL) profiling has been described in the gut of healthy subjects and patients with inflammatory bowel disease (IBD), the potential effects of these molecules on host cells have raised interest in the medical
Externí odkaz: https://doaj.org/article/8bc183c52be9498297f1a952e10f101e
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6
Akademický článek
Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota.
Autor: Cécilia Landman, Jean-Pierre Grill, Jean-Maurice Mallet, Philippe Marteau, Lydie Humbert, Eric Le Balc'h, Marie-Anne Maubert, Kevin Perez, Wahiba Chaara, Loic Brot, Laurent Beaugerie, Harry Sokol, Sophie Thenet, Dominique Rainteau, Philippe Seksik, Elodie Quévrain, Saint Antoine IBD Network
Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0202587 (2018)
BACKGROUND AND AIMS:N-acyl homoserine lactones (AHLs), which are autoinducer quorum-sensing molecules involved in the bacterial communication network, also interact with eukaryotic cells. Searching for these molecules in the context of inflammatory b
Externí odkaz: https://doaj.org/article/d873aaa554f74998a867df52cbd8a84f
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7
Gossip in the gut: Quorum sensing, a new player in the host-microbiota interactions
Autor: Philippe Seksik, Sophie Thenet, Doriane Aguanno, Jean-Pierre Grill, Nathan Grellier, Sandrine Pham, Véronique Carrière, Garance Coquant
Publikováno v: World Journal of Gastroenterology
World Journal of Gastroenterology, Baishideng Publishing Group Co. Limited, 2021, 27 (42), pp.7247-7270. ⟨10.3748/wjg.v27.i42.7247⟩
World Journal of Gastroenterology, 2021, 27 (42), pp.7247-7270. ⟨10.3748/wjg.v27.i42.7247⟩
International audience; Bacteria are known to communicate with each other and regulate their activities in social networks by secreting and sensing signaling molecules called autoinducers, a process known as quorum sensing (QS). This is a growing are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89aab3411006d0ada41daaf00953e1ca
https://pubmed.ncbi.nlm.nih.gov/34876787
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8
The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption
Autor: Jean-Pierre Grill, Céline Osinski, Philippe Seksik, Daniel Stockholm, Sophie Thenet, Véronique Carrière, Bárbara Graziela Postal, Garance Coquant, Margaux Wieckowski, Doriane Aguanno
Publikováno v: Tissue Barriers
article-version (VoR) Version of Record
The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major actors of the intestinal barrier, which is impaired in inflammatory bowel disease (IBD), along wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee536eec4432609de9f660d88a4be69
https://doi.org/10.1080/21688370.2020.1832877
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10
High-resolution mass spectrometry and partialde novosequencing constitute a useful approach for determining the profile of chemokine secretion following the stimulation of human intestinal epithelial cells
Autor: Joëlle Masliah, Estelle Capton, Marie Bachelet, Ginette Thomas, Dominique Rainteau, Jean Pierre Grill, Carlos Afonso, Marie-Anne Maubert, Elodie Quévrain, Jean-Claude Tabet, Germain Trugnan
Publikováno v: Rapid Communications in Mass Spectrometry. 27:2179-2187
RATIONALE Intestinal epithelial cells (IEC) secrete many chemokines in response to proinflammatory stimuli. We investigated their role in the mucosal inflammatory response in the intestine, by developing a non-targeted approach for analyzing the prof
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::546b2261a0a9f42c79d885835ca8a2c2
https://doi.org/10.1002/rcm.6680
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