Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Jean Pierre Gesson"'
Autor:
Ramona Barbour Eisen, Yves Bertrand, Lamine Boubakar, Jean-Pierre Gesson, Sylvie Pautrot, Rodolphe Vauzelle
Publikováno v:
Journal of the European Honors Council, Vol 2, Iss 1 (2018)
In this paper, we will describe the Cursus Master en Ingénierie (CMI) program, as well as the Formation à l’InGénierie par des Universités de REcherche (FIGURE) university network, and analyze its development and place in the French higher educ
Externí odkaz:
https://doaj.org/article/6550554e1ec44f29aeaa1f509ed935b4
Publikováno v:
E-Journal of Chemistry, Vol 8, Iss 3, Pp 1394-1400 (2011)
Inhibitors of histone deacetylases (HDACs) are patent inducers of differentiation and bear considerable potential as drugs for chemoprevention and treatment of cancer. In this paper, we have investigated three synthetic, inhibitors A1a,b, A2a. Analog
Externí odkaz:
https://doaj.org/article/82c3704bd4b24635a20202a526a83e50
Publikováno v:
Journal of Clinical Haematology. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0e6215382a3a05119b3efc277d6e41
https://doi.org/10.33696/haematology.1.002
https://doi.org/10.33696/haematology.1.002
Publikováno v:
E-Journal of Chemistry, Vol 8, Iss S1, Pp S79-S84 (2011)
The inhibition of HDAC (histone deacetylase) activity by specific inhibitors induces growth arrest, differentiation and apoptosis of transformed or several cancer cells. Some of these inhibitors are in clinical trial at phase I or phase II. The disco
Externí odkaz:
https://doaj.org/article/995007e3bd534c1cb5cd67c62251c4ac
Publikováno v:
Carbohydrate research. 487
N-ribosylation and N-mannosylation compounds have a great role in compounds activity as anticancer. The reaction of 2-thioxo-4-thiazolidinone (rhodanine) derivatives, as aglycon part, was done with ribofuranose and mannopyranose sugars (glycone part)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fc3fd820c3c865e5116a3466cfc870
https://pubmed.ncbi.nlm.nih.gov/31865252
https://pubmed.ncbi.nlm.nih.gov/31865252
Publikováno v:
E-Journal of Chemistry, Vol 8, Iss 3, Pp 1394-1400 (2011)
Inhibitors of histone deacetylases (HDACs) are patent inducers of differentiation and bear considerable potential as drugs for chemoprevention and treatment of cancer. In this paper, we have investigated three synthetic, inhibitors A1a,b, A2a. Analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89adf0aab8996875e0e75fead6c3d130
https://doaj.org/article/82c3704bd4b24635a20202a526a83e50
https://doaj.org/article/82c3704bd4b24635a20202a526a83e50
Autor:
Jean Pierre Gesson, Philippe Bertrand
Publikováno v:
The Journal of Organic Chemistry. 72:3596-3599
Click chemistry has became an important tool for molecular constructs such as biopolymers. During the development of biodegradable multifunctional poly(ethylene oxide) (PEO) polymers suitable for click chemistry in water, an unexpected reaction leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93964b320824501edf6fc314001c42c7
https://doi.org/10.1021/jo070131j
https://doi.org/10.1021/jo070131j
Publikováno v:
Tetrahedron Letters. 47:9305-9308
An efficient method for the synthesis of antitumor TMC-69-6H and related analogs which have been demonstrated to be phosphatase (PTP1B, VHR, and PP1) inhibitors, is reported. This strategy involves two key steps: a diastereoselective aldol reaction a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeb8a710dfdbeee0fe25407d66b86edf
https://doi.org/10.1016/j.tetlet.2006.10.102
https://doi.org/10.1016/j.tetlet.2006.10.102
Autor:
Jean-Pierre Gesson, Ulrich Koert, Christelle Faveau, Sandra Gebhardt, Tobias Mahnke, Martine Mondon
Publikováno v:
Tetrahedron Letters. 47:8305-8308
An analogue of the paclitaxel-like antimicrotubule agent laulimalide with a phenyl in place of the dihydropyran has been synthesized. The fragments C 1 –C 14 and C 15 –C 28 were coupled via a stereoselective intermolecular allylboration. Ring clo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7489232edaaf524f2c09369a999fe410
https://doi.org/10.1016/j.tetlet.2006.09.104
https://doi.org/10.1016/j.tetlet.2006.09.104
Publikováno v:
Tetrahedron Letters. 47:5547-5551
Treatment of 1-bromopropargylic amines affords the corresponding 1,1,1-trifluoro in one step in HF–SbF5 medium. 1-Bromo-1,1-difluoro or 2-bromo-1,1,1-trifluoro derivatives could also be prepared, depending on the reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54662d7a1ec3d4517307030ec231fe67
https://doi.org/10.1016/j.tetlet.2006.05.123
https://doi.org/10.1016/j.tetlet.2006.05.123